Institutional Repository of Key Laboratory of Behavioral Science, CAS
Identifying Topological Motif Patterns of Human Brain Functional Networks | |
Wei, Yongbin1,2,3; Liao, Xuhong1,2,4; Yan, Chaogan5,6; He, Yong1,2,4; Xia, Mingrui1,2,4 | |
摘要 | Recent imaging connectome studies demonstrated that the human functional brain network follows an efficient small-world topology with cohesive functional modules and highly connected hubs. However, the functional motif patterns that represent the underlying information flow remain largely unknown. Here, we investigated motif patterns within directed human functional brain networks, which were derived from resting-state functional magnetic resonance imaging data with controlled confounding hemodynamic latencies. We found several significantly recurring motifs within the network, including the two-node reciprocal motif and five classes of three-node motifs. These recurring motifs were distributed in distinct patterns to support intra-and inter-module functional connectivity, which also promoted integration and segregation in network organization. Moreover, the significant participation of several functional hubs in the recurring motifs exhibited their critical role in global integration. Collectively, our findings highlight the basic architecture governing brain network organization and provide insight into the information flow mechanism underlying intrinsic brain activities. (C) 2017 Wiley Periodicals, Inc. |
关键词 | connectome magnetic resonance imaging directed network resting-state breath-holding |
2017-05-01 | |
语种 | 英语 |
DOI | 10.1002/hbm.23557 |
发表期刊 | HUMAN BRAIN MAPPING |
ISSN | 1065-9471 |
卷号 | 38期号:5页码:2734-2750 |
期刊论文类型 | Article |
收录类别 | SCI |
WOS关键词 | BOLD FMRI ; SENSORY STIMULATION ; COMPLEX NETWORKS ; SIGNAL ; MRI ; NORMALIZATION ; ORGANIZATION ; ACTIVATION ; CAUSALITY ; SPACE |
WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
WOS研究方向 | Neurosciences & Neurology ; Radiology, Nuclear Medicine & Medical Imaging |
WOS类目 | Neurosciences ; Neuroimaging ; Radiology, Nuclear Medicine & Medical Imaging |
WOS记录号 | WOS:000404938700030 |
资助机构 | Natural Science Foundation of China(81401479 ; Beijing Natural Science Foundation(Z151100003915082 ; Fundamental Research Funds for the Central Universities(2015KJJCA13) ; 81671767 ; Z161100000216152 ; 91432115 ; Z161100000216125) ; 31521063 ; 11205041 ; 81671774) |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.psych.ac.cn/handle/311026/21642 |
专题 | 中国科学院行为科学重点实验室 |
作者单位 | 1.Beijing Normal Univ, Natl Key Lab Cognit Neurosci & Learning, Beijing, Peoples R China 2.Beijing Normal Univ, McGovern Inst Brain Res, IDG, Beijing, Peoples R China 3.Univ Med Ctr Utrecht, Brain Ctr Rudolf Magnus, Dept Psychiat, Utrecht, Netherlands 4.Beijing Normal Univ, Beijing Key Lab Brain Imaging & Connect, Beijing 100875, Peoples R China 5.Inst Psychol, CAS Key Lab Behav Sci, Beijing, Peoples R China 6.Chinese Acad Sci, Inst Psychol, Magnet Resonance Imaging Res Ctr, Beijing, Peoples R China |
推荐引用方式 GB/T 7714 | Wei, Yongbin,Liao, Xuhong,Yan, Chaogan,et al. Identifying Topological Motif Patterns of Human Brain Functional Networks[J]. HUMAN BRAIN MAPPING,2017,38(5):2734-2750. |
APA | Wei, Yongbin,Liao, Xuhong,Yan, Chaogan,He, Yong,&Xia, Mingrui.(2017).Identifying Topological Motif Patterns of Human Brain Functional Networks.HUMAN BRAIN MAPPING,38(5),2734-2750. |
MLA | Wei, Yongbin,et al."Identifying Topological Motif Patterns of Human Brain Functional Networks".HUMAN BRAIN MAPPING 38.5(2017):2734-2750. |
条目包含的文件 | ||||||
文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
Identifying Topologi(1247KB) | 期刊论文 | 出版稿 | 限制开放 | CC BY-NC-SA | 请求全文 |
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