PSYCH OpenIR  > 中国科学院行为科学重点实验室
Identifying Topological Motif Patterns of Human Brain Functional Networks
Wei, Yongbin1,2,3; Liao, Xuhong1,2,4; Yan, Chaogan5,6; He, Yong1,2,4; Xia, Mingrui1,2,4
2017-05-01
Source PublicationHUMAN BRAIN MAPPING
ISSN1065-9471
SubtypeArticle
Volume38Issue:5Pages:2734-2750
Abstract

Recent imaging connectome studies demonstrated that the human functional brain network follows an efficient small-world topology with cohesive functional modules and highly connected hubs. However, the functional motif patterns that represent the underlying information flow remain largely unknown. Here, we investigated motif patterns within directed human functional brain networks, which were derived from resting-state functional magnetic resonance imaging data with controlled confounding hemodynamic latencies. We found several significantly recurring motifs within the network, including the two-node reciprocal motif and five classes of three-node motifs. These recurring motifs were distributed in distinct patterns to support intra-and inter-module functional connectivity, which also promoted integration and segregation in network organization. Moreover, the significant participation of several functional hubs in the recurring motifs exhibited their critical role in global integration. Collectively, our findings highlight the basic architecture governing brain network organization and provide insight into the information flow mechanism underlying intrinsic brain activities. (C) 2017 Wiley Periodicals, Inc.

Keywordconnectome magnetic resonance imaging directed network resting-state breath-holding
DOI10.1002/hbm.23557
Indexed BySCI
Language英语
Funding OrganizationNatural Science Foundation of China(81401479 ; Beijing Natural Science Foundation(Z151100003915082 ; Fundamental Research Funds for the Central Universities(2015KJJCA13) ; Hundred Talents Program of the Chinese Academy of Sciences ; 81671767 ; Z161100000216152 ; 91432115 ; Z161100000216125) ; 31521063 ; 11205041 ; 81671774)
WOS Research AreaNeurosciences & Neurology ; Radiology, Nuclear Medicine & Medical Imaging
WOS SubjectNeurosciences ; Neuroimaging ; Radiology, Nuclear Medicine & Medical Imaging
WOS IDWOS:000404938700030
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
WOS KeywordBOLD FMRI ; SENSORY STIMULATION ; COMPLEX NETWORKS ; SIGNAL ; MRI ; NORMALIZATION ; ORGANIZATION ; ACTIVATION ; CAUSALITY ; SPACE
Citation statistics
Cited Times:3[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.psych.ac.cn/handle/311026/21642
Collection中国科学院行为科学重点实验室
Affiliation1.Beijing Normal Univ, Natl Key Lab Cognit Neurosci & Learning, Beijing, Peoples R China
2.Beijing Normal Univ, McGovern Inst Brain Res, IDG, Beijing, Peoples R China
3.Univ Med Ctr Utrecht, Brain Ctr Rudolf Magnus, Dept Psychiat, Utrecht, Netherlands
4.Beijing Normal Univ, Beijing Key Lab Brain Imaging & Connect, Beijing 100875, Peoples R China
5.Inst Psychol, CAS Key Lab Behav Sci, Beijing, Peoples R China
6.Chinese Acad Sci, Inst Psychol, Magnet Resonance Imaging Res Ctr, Beijing, Peoples R China
Recommended Citation
GB/T 7714
Wei, Yongbin,Liao, Xuhong,Yan, Chaogan,et al. Identifying Topological Motif Patterns of Human Brain Functional Networks[J]. HUMAN BRAIN MAPPING,2017,38(5):2734-2750.
APA Wei, Yongbin,Liao, Xuhong,Yan, Chaogan,He, Yong,&Xia, Mingrui.(2017).Identifying Topological Motif Patterns of Human Brain Functional Networks.HUMAN BRAIN MAPPING,38(5),2734-2750.
MLA Wei, Yongbin,et al."Identifying Topological Motif Patterns of Human Brain Functional Networks".HUMAN BRAIN MAPPING 38.5(2017):2734-2750.
Files in This Item:
File Name/Size DocType Version Access License
Identifying Topologi(1247KB)期刊论文出版稿限制开放CC BY-NC-SAView Application Full Text
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Wei, Yongbin]'s Articles
[Liao, Xuhong]'s Articles
[Yan, Chaogan]'s Articles
Baidu academic
Similar articles in Baidu academic
[Wei, Yongbin]'s Articles
[Liao, Xuhong]'s Articles
[Yan, Chaogan]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Wei, Yongbin]'s Articles
[Liao, Xuhong]'s Articles
[Yan, Chaogan]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: Identifying Topological Motif Patterns of Human Brain Functional Networks.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.