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Alterations in brain activation in response to prolonged morphine withdrawal-induced behavioral inflexibility in rats
Piao, Chengji1,2,3; Liu, Tiane1,2; Ma, Lian1,2; Ding, Xuekun1,2; Wang, Xingyue1,2; Chen, Xing1,2; Duan, Ying1,2; Sui, Nan1,2; Liang, Jing1,2; Nan Sui; Jing Liang
2017-10-01
Source PublicationPSYCHOPHARMACOLOGY
Correspondent Emailsuin@psych.ac.cn ; liangj@psych.ac.cn
ISSN0033-3158
SubtypeArticle
Volume234Issue:19Pages:2941-2953
Abstract

The inability to stop a repetitive maladaptive behavior is a main problem in addictive disorders. Neuroadaptations that are associated with behavioral inflexibility may be involved in compulsive drug use.

KeywordMorphine withdrawal Reversal learning Orbitalfrontal cortex Medial prefrontal cortex Striatum
DOI10.1007/s00213-017-4689-3
Indexed BySCI
Language英语
Funding OrganizationNational Natural Science Foundation of China(31271098 ; National Key Basic Research Program of China(2015CB553501) ; Beijing Natural Science Foundation(5162023) ; 31571108)
WOS Research AreaNeurosciences & Neurology ; Pharmacology & Pharmacy ; Psychiatry
WOS SubjectNeurosciences ; Pharmacology & Pharmacy ; Psychiatry
WOS IDWOS:000409895900009
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
WOS KeywordMEDIAL PREFRONTAL CORTEX ; COCAINE-EXPERIENCED RATS ; GLUR1 RECEPTOR SUBUNIT ; TIME-DEPENDENT CHANGES ; DORSOMEDIAL STRIATUM ; ORBITOFRONTAL CORTEX ; COGNITIVE FLEXIBILITY ; INDUCED REINSTATEMENT ; LEARNING-DEFICITS ; SIGNALING PATHWAY
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Document Type期刊论文
Identifierhttp://ir.psych.ac.cn/handle/311026/21900
Collection中国科学院心理健康重点实验室
Corresponding AuthorNan Sui; Jing Liang
Affiliation1.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China
2.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China
3.Sinodanish Ctr Educ & Res, Beijing, Peoples R China
First Author AffilicationKey Laboratory of Mental Health, CAS
Recommended Citation
GB/T 7714
Piao, Chengji,Liu, Tiane,Ma, Lian,et al. Alterations in brain activation in response to prolonged morphine withdrawal-induced behavioral inflexibility in rats[J]. PSYCHOPHARMACOLOGY,2017,234(19):2941-2953.
APA Piao, Chengji.,Liu, Tiane.,Ma, Lian.,Ding, Xuekun.,Wang, Xingyue.,...&Jing Liang.(2017).Alterations in brain activation in response to prolonged morphine withdrawal-induced behavioral inflexibility in rats.PSYCHOPHARMACOLOGY,234(19),2941-2953.
MLA Piao, Chengji,et al."Alterations in brain activation in response to prolonged morphine withdrawal-induced behavioral inflexibility in rats".PSYCHOPHARMACOLOGY 234.19(2017):2941-2953.
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