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Repetitive Transcranial Magnetic Stimulation (rTMS) Modulates Lipid Metabolism in Aging Adults
Ren, Weicong1,2,3; Ma, Jiang4; Li, Juan3; Zhang, Zhijie1,2; Wang, Mingwei2,5; Zhijie Zhang; Mingwei Wang
2017-10-17
发表期刊FRONTIERS IN AGING NEUROSCIENCE
通讯作者邮箱zhangzhj2002@sina.com ; mwei99@yahoo.com
ISSN1663-4365
文章类型Article
卷号9期号:0页码:334-340
摘要

Hyperlipidemia, one of the cardiovascular (CV) risk factors, is associated with an increase in the risk for dementia. Repetitive transcranial magnetic stimulation (rTMS) was applied over the right dorsolateral prefrontal cortex (DLPFC) to modulate serum lipid levels in older adults. Participants received 10 sessions of rTMS or sham stimulation intervention within 2 weeks. The serum lipid and thyroid hormone-related endocrine levels were assessed before and after the treatment. We found that rTMS significantly decreased serum lipid levels, including the total cholesterol (CHO) and triglyceride (TG); meanwhile, it also increased the thyroid-stimulating hormone (TSH) as well as thyroxine (T4) levels. This suggests that rTMS modulated the serum lipid metabolism by altering activity in the hypothalamo-pituitary-thyroid (HPT) axis. The trial was registered on the website of Chinese Clinical Trial Registry (http://www.chictr.org.cn).

关键词rTMS older adults cardiovascular disease lipid metabolism HPT axis
DOI10.3389/fnagi.2017.00334
收录类别SCI
语种英语
WOS研究方向Geriatrics & Gerontology ; Neurosciences & Neurology
WOS类目Geriatrics & Gerontology ; Neurosciences
WOS记录号WOS:000413140900002
WOS标题词Science & Technology ; Life Sciences & Biomedicine
关键词[WOS]NONINVASIVE BRAIN-STIMULATION ; MILD COGNITIVE IMPAIRMENT ; ALZHEIMERS-DISEASE ; HORMONE-LEVELS ; CHRONIC STRESS ; MOTOR CORTEX ; RISK-FACTORS ; CHOLESTEROL ; METAANALYSIS ; HYPERTENSION
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文献类型期刊论文
条目标识符http://ir.psych.ac.cn/handle/311026/21944
专题中国科学院心理健康重点实验室
通讯作者Zhijie Zhang; Mingwei Wang
作者单位1.Hebei Normal Univ, Dept Psychol, Shijiazhuang, Hebei, Peoples R China
2.Hebei Med Univ, Key Lab Brain Aging & Cognit Neurosci Hebei Prov, Shijiazhuang, Hebei, Peoples R China
3.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Ctr Aging Psychol, Beijing, Peoples R China
4.First Hosp Shijiazhuang, Dept Rehabil, Shijiazhuang, Hebei, Peoples R China
5.Hebei Med Univ, Hosp 1, Dept Neurol, Shijiazhuang, Hebei, Peoples R China
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Ren, Weicong,Ma, Jiang,Li, Juan,et al. Repetitive Transcranial Magnetic Stimulation (rTMS) Modulates Lipid Metabolism in Aging Adults[J]. FRONTIERS IN AGING NEUROSCIENCE,2017,9(0):334-340.
APA Ren, Weicong.,Ma, Jiang.,Li, Juan.,Zhang, Zhijie.,Wang, Mingwei.,...&Mingwei Wang.(2017).Repetitive Transcranial Magnetic Stimulation (rTMS) Modulates Lipid Metabolism in Aging Adults.FRONTIERS IN AGING NEUROSCIENCE,9(0),334-340.
MLA Ren, Weicong,et al."Repetitive Transcranial Magnetic Stimulation (rTMS) Modulates Lipid Metabolism in Aging Adults".FRONTIERS IN AGING NEUROSCIENCE 9.0(2017):334-340.
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