PSYCH OpenIR  > 中国科学院心理健康重点实验室
Following Instructions in Patients With Schizophrenia: The Benefits of Actions at Encoding and Recall
Lui, Simon S. Y.1,2; Yang, Tian-Xiao2,3; Ng, Chris L. Y.1; Wong, Peony T. Y.1; Wong, Jessica O. Y.1; Ettinger, Ulrich4; Cheung, Eric F. C.1; Chan, Raymond C. K.2,5
2018
Source PublicationSCHIZOPHRENIA BULLETIN
Correspondent Emailrckchan@psych.ac.cn
ISSN0586-7614
SubtypeArticle
Volume44Issue:1Pages:137-146
Contribution Rank2
Abstract

The ability to follow spoken instructions is important to everyday functioning but has seldom been studied in patients with schizophrenia (SZ). Recent evidence suggests that action-based processing may facilitate the ability to follow instructions, which relies largely on working memory. In this study, we tested the hypothesis that SZ patients may also benefit from action-based advantages in following instructions. Forty-eight clinically stable SZ patients and 48 demographic- and IQ-matched controls completed a following spoken instruction span task involving varied encoding and recall conditions. While SZ patients were impaired in the overall performance of following spoken instructions, this deficit could be attributed to working memory impairment. More importantly, SZ patients showed action-based advantages both at the encoding and retrieval stage to the same extent as healthy controls. Specifically, both healthy controls and SZ patients showed improved memory performance when they additionally performed the actions, or watched the experimenter carrying out the actions compared with simply listening to spoken instructions during the encoding stage. During the retrieval stage, memory was improved when they recalled the instructions by physical enactment compared with oral repetition. The present study provides the first empirical evidence for the impairment in the ability to follow instructions in SZ. We have shown that involving action-based processing in the encoding and retrieval stage facilitated memory of instructions, indicating that the enactment advantage in working memory also applies to SZ patients. These findings provide useful insights for clinical interventions and cognitive remediation for SZ patients.

Keywordschizophrenia working memory enacted-recall advantage subject-performed task effect experimenter-performed task effect
DOI10.1093/schbul/sbx026
Indexed BySCI ; SSCI
Language英语
Funding OrganizationBeijing Training Project for the Leading Talents in S T(Z151100000315020) ; Beijing Municipal Science & Technology Commission(Z161100000216138) ; National Basic Research Programme of China(2016YFC0906402) ; CAS key Laboratory of Mental Health, Institute of Psychology ; CAS/SAFEA International Partnership Programme for Creative Research Teams(Y2CX131003) ; National Natural Science Foundation of China(31400873) ; CAS Key Laboratory of Mental Health, Institute of Psychology(KLMH2015ZG02)
WOS Research AreaPsychiatry
WOS SubjectPsychiatry
WOS IDWOS:000422833500018
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
WOS KeywordSUBJECT-PERFORMED TASKS ; WORKING-MEMORY ; ACTION EVENTS ; MOTOR ACTION ; ACTION PLANS ; DYSFUNCTION ; PERCEPTION ; ENACTMENT
Citation statistics
Cited Times:1[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.psych.ac.cn/handle/311026/22299
Collection中国科学院心理健康重点实验室
Affiliation1.Castle Peak Hosp, Hong Kong, Hong Kong, Peoples R China
2.Chinese Acad Sci, Inst Psychol, Neuropsychol & Appl Cognit Neurosci Lab, CAS Key Lab Mental Hlth, Beijing, Peoples R China
3.Univ Chinese Acad Sci, Beijing, Peoples R China
4.Univ Bonn, Dept Psychol, Bonn, Germany
5.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China
Recommended Citation
GB/T 7714
Lui, Simon S. Y.,Yang, Tian-Xiao,Ng, Chris L. Y.,et al. Following Instructions in Patients With Schizophrenia: The Benefits of Actions at Encoding and Recall[J]. SCHIZOPHRENIA BULLETIN,2018,44(1):137-146.
APA Lui, Simon S. Y..,Yang, Tian-Xiao.,Ng, Chris L. Y..,Wong, Peony T. Y..,Wong, Jessica O. Y..,...&Chan, Raymond C. K..(2018).Following Instructions in Patients With Schizophrenia: The Benefits of Actions at Encoding and Recall.SCHIZOPHRENIA BULLETIN,44(1),137-146.
MLA Lui, Simon S. Y.,et al."Following Instructions in Patients With Schizophrenia: The Benefits of Actions at Encoding and Recall".SCHIZOPHRENIA BULLETIN 44.1(2018):137-146.
Files in This Item:
File Name/Size DocType Version Access License
Following Instructio(159KB)期刊论文作者接受稿限制开放CC BY-NC-SAView Application Full Text
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Lui, Simon S. Y.]'s Articles
[Yang, Tian-Xiao]'s Articles
[Ng, Chris L. Y.]'s Articles
Baidu academic
Similar articles in Baidu academic
[Lui, Simon S. Y.]'s Articles
[Yang, Tian-Xiao]'s Articles
[Ng, Chris L. Y.]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Lui, Simon S. Y.]'s Articles
[Yang, Tian-Xiao]'s Articles
[Ng, Chris L. Y.]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: Following Instructions in Patients With Schizophrenia_ The Benefits of Actions at Encoding and Recall.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.