PSYCH OpenIR  > 健康与遗传心理学研究室
Intrinsic spontaneous brain activity predicts individual variability in associative memory in older adults
Zheng Zhiwei1,2; Li Rui1,2,3; Xiao Fengqiu4; He Rongqiao5; Zhang Shouzi6; Li Juan1,2,3,5
First AuthorZheng Zhiwei
2018
Source PublicationPsych Journal
Correspondent Emaillijuan@psych.ac.cn
SubtypeArticle
Issue2Pages:1-15
QuartileQ3
Contribution Rank1
Abstract

Older adults demonstrate notable individual differences in associative memory. Here, resting-state functional magnetic resonance imaging (rsfMRI) was used to investigate whether intrinsic brain activity at rest could predict individual differences in associative memory among cognitively healthy older adults. Regional amplitude of low-frequency fluctuations (ALFF) analysis and a correlation-based resting-state functional connectivity (RSFC) approach were used to analyze data acquired from 102 cognitively normal elderly who completed the paired-associative learning test (PALT) and underwent fMRI scans. Participants were divided into two groups based on the retrospective self-reports on whether or not they utilized encoding strategies during the PALT. The behavioral results revealed better associative memory performance in the participants who reported utilizing memory strategies compared with participants who reported not doing so. The fMRI results showed that higher associative memory performance was associated with greater functional connectivity between the right superior frontal gyrus and the right posterior cerebellum lobe in the strategy group. The regional ALFF values in the right superior frontal gyrus were linked to associative memory performance in the no-strategy group. These findings suggest that the regional spontaneous fluctuations and functional connectivity during rest may subserve the individual differences in the associative memory in older adults, and that this is modulated by self-initiated memory strategy use.

Keywordassociative memory elderly individual differences memory strategies resting-state functional magnetic resonance imaging (rsfMRI)
DOI10.1002/pchj.212
Indexed BySSCI ; SSCI
Language英语
Citation statistics
Document Type期刊论文
Identifierhttp://ir.psych.ac.cn/handle/311026/25691
Collection健康与遗传心理学研究室
Corresponding AuthorLi Juan
Affiliation1.Center on Aging Psychology, CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China
2.Department of Psychology, University of Chinese Academy of Sciences, Beijing, China
3.Magnetic Resonance Imaging Research Center, Institute of Psychology, Chinese Academy of Sciences, Beijing, China
4.China National Children’s Center, Beijing, China
5.State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
6.Beijing Geriatric Hospital, Beijing, China
First Author AffilicationInstitute of Psychology, Chinese Academy of Sciences
Corresponding Author AffilicationInstitute of Psychology, Chinese Academy of Sciences
Recommended Citation
GB/T 7714
Zheng Zhiwei,Li Rui,Xiao Fengqiu,et al. Intrinsic spontaneous brain activity predicts individual variability in associative memory in older adults[J]. Psych Journal,2018(2):1-15.
APA Zheng Zhiwei,Li Rui,Xiao Fengqiu,He Rongqiao,Zhang Shouzi,&Li Juan.(2018).Intrinsic spontaneous brain activity predicts individual variability in associative memory in older adults.Psych Journal(2),1-15.
MLA Zheng Zhiwei,et al."Intrinsic spontaneous brain activity predicts individual variability in associative memory in older adults".Psych Journal .2(2018):1-15.
Files in This Item:
File Name/Size DocType Version Access License
Zheng_et_al-2017-Psy(557KB)期刊论文出版稿限制开放CC BY-NC-SAView Application Full Text
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Zheng Zhiwei]'s Articles
[Li Rui]'s Articles
[Xiao Fengqiu]'s Articles
Baidu academic
Similar articles in Baidu academic
[Zheng Zhiwei]'s Articles
[Li Rui]'s Articles
[Xiao Fengqiu]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Zheng Zhiwei]'s Articles
[Li Rui]'s Articles
[Xiao Fengqiu]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: Zheng_et_al-2017-PsyCh_Journal.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.