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Mindfulness-based relapse prevention combined with virtual reality cue exposure for methamphetamine use disorder: study protocol for a randomized controlled trial
Chen, Xijing1,2; Wang, Dongmei1,2; Zhou, Lidan1,2; Winkler, Markus3; Pauli, Paul3,4; Sui, Nan1,2; Li, Yonghui1,2
第一作者Chen, Xijing
2018
发表期刊Contemporary Clinical Trials
通讯作者邮箱wangdm@psych.ac.cn
ISSN1551-7144
文章类型Article
期号70页码:99-105
Q分类Q3
产权排序1
摘要

Background

Mindfulness-based relapse prevention (MBRP) is a method that combines cognitive behavioral relapse prevention with mindfulness practice. Research shows that MBRP can effectively reduce negative emotions and craving in people with substance use disorders (SUDs). An important part of MBRP is to practice mindfulness meditation to cope with high-risk situations for relapse, such as stimuli and situations associated with drug taking. Virtual reality cue exposure (VRCE) may be a complementary approach to MBRP as it allows for controlled and graded presentations of various high-risk situations with distal and proximal drug cues. The aim of the study is to investigate the effects of MBRP combined with VRCE, in comparison to MBRP alone or treatment as usual, on craving and emotional responses in people with methamphetamine use disorders.

Method/design

The study is a parallel randomized controlled study including 180 participants with methamphetamine use disorders. Three parallel groups will receive 8 weeks of MBRP combined with VRCE, MBRP alone, or treatment as usual, respectively. Craving, virtual cue reactivity, anxiety, depression, emotion regulation, mindfulness and drug-related attention bias will be assessed at pre-treatment, post-treatment, and 3 and 6 months of follow-up.

Discussion

This innovative study aims at investigating the effects of MBRP combined with VRCE in people with SUDs. The combined intervention may have important clinical implications for relapse prevention due to its ease of application and high cost-effectiveness. This study may also stimulate research on the neuronal and psychological mechanisms of MBRP in drug addiction.

Trial registration Number. ChiCTR-INR-17013041.

关键词Mindfulness-based Relapse Prevention Virtual Reality Cue Exposure Randomized Controlled Trial Substance Use Disorder Methamphetamine Addiction
DOIhttps://doi.org/10.1016/j.cct.2018.04.006
收录类别SCI
语种英语
引用统计
文献类型期刊论文
条目标识符http://ir.psych.ac.cn/handle/311026/25705
专题中国科学院心理健康重点实验室
通讯作者Wang, Dongmei
作者单位1.CAS Key Laboratory of Mental Health, Institute of Psychology
2.Department of Psychology, University of Chinese Academy of Sciences
3.Department of Psychology (Biological Psychology, Clinical Psychology, and Psychotherapy), University of Würzburg, Würzburg, Germany
4.Center of Mental Health, Medical Faculty, University of Würzburg, Würzburg, Germany
推荐引用方式
GB/T 7714
Chen, Xijing,Wang, Dongmei,Zhou, Lidan,et al. Mindfulness-based relapse prevention combined with virtual reality cue exposure for methamphetamine use disorder: study protocol for a randomized controlled trial[J]. Contemporary Clinical Trials,2018(70):99-105.
APA Chen, Xijing.,Wang, Dongmei.,Zhou, Lidan.,Winkler, Markus.,Pauli, Paul.,...&Li, Yonghui.(2018).Mindfulness-based relapse prevention combined with virtual reality cue exposure for methamphetamine use disorder: study protocol for a randomized controlled trial.Contemporary Clinical Trials(70),99-105.
MLA Chen, Xijing,et al."Mindfulness-based relapse prevention combined with virtual reality cue exposure for methamphetamine use disorder: study protocol for a randomized controlled trial".Contemporary Clinical Trials .70(2018):99-105.
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