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|Mindfulness-based relapse prevention combined with virtual reality cue exposure for methamphetamine use disorder: study protocol for a randomized controlled trial|
|Chen, Xijing1,2; Wang, Dongmei1,2; Zhou, Lidan1,2; Winkler, Markus3; Pauli, Paul3,4; Sui, Nan1,2; Li, Yonghui1,2|
|发表期刊||Contemporary Clinical Trials|
Mindfulness-based relapse prevention (MBRP) is a method that combines cognitive behavioral relapse prevention with mindfulness practice. Research shows that MBRP can effectively reduce negative emotions and craving in people with substance use disorders (SUDs). An important part of MBRP is to practice mindfulness meditation to cope with high-risk situations for relapse, such as stimuli and situations associated with drug taking. Virtual reality cue exposure (VRCE) may be a complementary approach to MBRP as it allows for controlled and graded presentations of various high-risk situations with distal and proximal drug cues. The aim of the study is to investigate the effects of MBRP combined with VRCE, in comparison to MBRP alone or treatment as usual, on craving and emotional responses in people with methamphetamine use disorders.
The study is a parallel randomized controlled study including 180 participants with methamphetamine use disorders. Three parallel groups will receive 8 weeks of MBRP combined with VRCE, MBRP alone, or treatment as usual, respectively. Craving, virtual cue reactivity, anxiety, depression, emotion regulation, mindfulness and drug-related attention bias will be assessed at pre-treatment, post-treatment, and 3 and 6 months of follow-up.
This innovative study aims at investigating the effects of MBRP combined with VRCE in people with SUDs. The combined intervention may have important clinical implications for relapse prevention due to its ease of application and high cost-effectiveness. This study may also stimulate research on the neuronal and psychological mechanisms of MBRP in drug addiction.
Trial registration Number. ChiCTR-INR-17013041.
|关键词||Mindfulness-based Relapse Prevention Virtual Reality Cue Exposure Randomized Controlled Trial Substance Use Disorder Methamphetamine Addiction|
|作者单位||1.CAS Key Laboratory of Mental Health, Institute of Psychology|
2.Department of Psychology, University of Chinese Academy of Sciences
3.Department of Psychology (Biological Psychology, Clinical Psychology, and Psychotherapy), University of Würzburg, Würzburg, Germany
4.Center of Mental Health, Medical Faculty, University of Würzburg, Würzburg, Germany
|Chen, Xijing,Wang, Dongmei,Zhou, Lidan,et al. Mindfulness-based relapse prevention combined with virtual reality cue exposure for methamphetamine use disorder: study protocol for a randomized controlled trial[J]. Contemporary Clinical Trials,2018(70):99-105.|
|APA||Chen, Xijing.,Wang, Dongmei.,Zhou, Lidan.,Winkler, Markus.,Pauli, Paul.,...&Li, Yonghui.(2018).Mindfulness-based relapse prevention combined with virtual reality cue exposure for methamphetamine use disorder: study protocol for a randomized controlled trial.Contemporary Clinical Trials(70),99-105.|
|MLA||Chen, Xijing,et al."Mindfulness-based relapse prevention combined with virtual reality cue exposure for methamphetamine use disorder: study protocol for a randomized controlled trial".Contemporary Clinical Trials .70(2018):99-105.|
|Contemporary Clinica（348KB）||期刊论文||作者接受稿||开放获取||CC BY-NC-SA||请求全文|
|Contemporary Clinica（285KB）||期刊论文||作者接受稿||开放获取||CC BY-NC-SA||请求全文|