Institutional Repository of Key Laboratory of Mental Health, CAS
| A DRD2/ANNK1-COMT Interaction, Consisting of Functional Variants, Confers Risk of Post-traumatic Stress Disorder in Traumatized Chinese | |
Zhang, Kunlin1,2,3 ; Wang, Li1,2,3; Cao, Chengqi1,2,4; Li, Gen1,2,3; Fang, Ruojiao1,2,3; Liu, Ping5; Luo, Shu5; Zhang, Xiangyang1,2,3; Liberzon, Israel6,7,8; Li Wang
| |
| 通讯作者邮箱 | wangli1@psych.ac.cn |
| 心理所单位排序 | 1 |
| 摘要 | Objective: Post-traumatic stress disorder (PTSD) is a trauma-and stress-related psychiatric syndrome that occurs after exposure to extraordinary stressors. The neurotransmitter dopamine (DA) plays important roles in neurobiological processes like reward and stress, and a link between PTSD and the dopaminergic system has been reported. Thus, the investigation of an association between PTSD and gene-gene interaction (epistasis) within dopaminergic genes could uncover the genetic basis of dopamine-related PTSD symptomatology and contribute to precision medicine. |
| 关键词 | post-traumatic stress disorder (PTSD) dopaminergic genes DRD2/ANNK1-COMT interaction modulate functional variants |
| 2018-04-30 | |
| 语种 | 英语 |
| DOI | 10.3389/fpsyt.2018.00170 |
| 发表期刊 | FRONTIERS IN PSYCHIATRY
 |
| ISSN | 1664-0640 |
| 卷号 | 9页码:1-9 |
| 期刊论文类型 | Article |
| 收录类别 | SCI ; SSCI |
| WOS关键词 | HUMAN GENETIC-VARIATION ; EARTHQUAKE SURVIVORS ; COMPLEX TRAITS ; RECEPTOR GENE ; DOPAMINE ; PTSD ; ASSOCIATION ; POLYMORPHISMS ; SYMPTOMS ; DEPRESSION |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| WOS研究方向 | Psychiatry |
| WOS类目 | Psychiatry |
| WOS记录号 | WOS:000431132500001 |
| 资助机构 | External Cooperation Program of Chinese Academy of Sciences(153111KYSB20160036) ; National Natural Science Foundation of China(31471004 ; Key Project of Research Base of Humanities and Social Sciences of Ministry of Education(16JJD190006) ; 31470070 ; 31271099) |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.psych.ac.cn/handle/311026/26200 |
| 专题 | 中国科学院心理健康重点实验室 |
| 通讯作者 | Li Wang |
| 作者单位 | 1.Chinese Acad Sci, Key Lab Mental Hlth, Inst Psychol, Lab Traumat Stress Studies, Beijing, Peoples R China 2.Chinese Acad Sci, Key Lab Mental Hlth, Inst Psychol, Ctr Genet & BioMed Informat Res, Beijing, Peoples R China 3.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China 4.Shenzhen Univ, Shenzhen Key Lab Affect & Social Cognit Sci, Shenzhen, Peoples R China 5.Peoples Hosp Deyang, Deyang, Peoples R China 6.Univ Michigan, Dept Psychiat, Ann Arbor, MI 48109 USA 7.VA Ann Arbor Healthcare Syst, Mental Hlth Serv, Ann Arbor, MI USA 8.Univ Michigan, Dept Psychol, Ann Arbor, MI USA |
| 推荐引用方式 GB/T 7714 | Zhang, Kunlin,Wang, Li,Cao, Chengqi,et al. A DRD2/ANNK1-COMT Interaction, Consisting of Functional Variants, Confers Risk of Post-traumatic Stress Disorder in Traumatized Chinese[J]. FRONTIERS IN PSYCHIATRY,2018,9:1-9. |
| APA | Zhang, Kunlin.,Wang, Li.,Cao, Chengqi.,Li, Gen.,Fang, Ruojiao.,...&Li Wang.(2018).A DRD2/ANNK1-COMT Interaction, Consisting of Functional Variants, Confers Risk of Post-traumatic Stress Disorder in Traumatized Chinese.FRONTIERS IN PSYCHIATRY,9,1-9. |
| MLA | Zhang, Kunlin,et al."A DRD2/ANNK1-COMT Interaction, Consisting of Functional Variants, Confers Risk of Post-traumatic Stress Disorder in Traumatized Chinese".FRONTIERS IN PSYCHIATRY 9(2018):1-9. |
| 条目包含的文件 | ||||||
| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| A DRD2_ANNK1-COMT In（637KB） | 期刊论文 | 出版稿 | 限制开放 | CC BY-NC-SA | 请求全文 | |
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。
修改评论