PSYCH OpenIR  > 中国科学院心理健康重点实验室
Placebo Analgesia in Rodents
Jian-You Guo; Jin-Yan Wang; Fei Luo
Source PublicationPlacebo and Pain From Bench to Bedside
2014
Pages15-23
Publisher不详
Publication Place不详
KeywordPlacebo Analgesia Rodents Morphine Antidepressant Opioid Receptor Pros Cons
Abstract

The placebo effect is a fascinating yet puzzling phenomenon which has challenged investigators over the past 50 years. Some researchers have initiated investigations of the effects of placebos in animals, and have shown that associative learning is a major way to elicit placebo responses. Pain is the field in which most of the placebo research has been performed. In contrast to numerous studies involving human subjects, the available literature on placebo-induced analgesia in animal models is rare. This chapter introduces a special drug-conditioning procedure, a cue paired with morphine or aspirin, eliciting analgesic responses in a hot plate test. This established placebo analgesia was considered to be transferable from pain to depression and could produce a significant antidepressant effect in a test on depression in mice. Furthermore, the opioid placebo analgesia was found to be mediated exclusively through a μ-opioid receptor in the rat. The pros and cons of studying placebo in animal models are also discussed at the end of this chapter.

Language英语
Document Type专著章节, 文集论文
Identifierhttp://ir.psych.ac.cn/handle/311026/26551
Collection中国科学院心理健康重点实验室
AffiliationKey Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, P. R. China
Recommended Citation
GB/T 7714
Jian-You Guo,Jin-Yan Wang,Fei Luo. Placebo Analgesia in Rodents. 2014.
Files in This Item:
File Name/Size DocType Version Access License
Placebo Analgesia in(765KB)专著章节, 文集论文 限制开放CC BY-NC-SAView Application Full Text
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Jian-You Guo]'s Articles
[Jin-Yan Wang]'s Articles
[Fei Luo]'s Articles
Baidu academic
Similar articles in Baidu academic
[Jian-You Guo]'s Articles
[Jin-Yan Wang]'s Articles
[Fei Luo]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Jian-You Guo]'s Articles
[Jin-Yan Wang]'s Articles
[Fei Luo]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: Placebo Analgesia in Rodents.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.