PSYCH OpenIR  > 中国科学院心理健康重点实验室
Alternative TitleSubtypes of negative symptoms in schizophrenia: Evidence from cluster analysis of the CAINS
谢东杰; 陈楚侨
Conference Name第二十一届全国心理学学术会议
Source Publication摘要集-第二十一届全国心理学学术会议
Conference Date10.30-11.2
Conference Place北京
Contribution Rank1


Other Abstract

Abstract: Impaired empathy is one of the major dysfunctions commonly found in patients with schizophrenia, with alexithymia being its possible underlying cause. To test this speculation, we administered the Interpersonal Reactivity Index (IRI) to measure cognitive and affective empathy, the Toronto Alexithymia Scale (TAS) to measure alexithymia, and the Chapman scales (Chapman Scale for Social Anhedonia, CRSAS; Chapman Scale for Physical Anhedonia Scale, CPAS) to evaluate an individual’s schizotypy score. Atotal of 811 college students were queried on the IRI, TAS, and the Chapman scales. Networkanalysis method was used to explore the relationships of the above factors. In particular,regularized partial correlation (LASSO) networks of male and female participants were estimated. In the visualization of the model, items are displayed as nodes, edges represent regularized partial correlations between the nodes. Centrality denotes a node's connectedness with other nodes in the network. Negative edges were found among nodes belonging to the IRI and Chapman scale as well as among nodes belonging to TAS and IRI. Node representing the subscale TAS-F1 (“difficulty identifying feelings”) showed the highest strength centrality score. The network accuracy and stability were tested, edges and node centrality order were accurately estimated. Results show that 1) the IRI-F1(“personal distress”) is associated with TAS-F1(“difficulty identifying feelings”), while perspective taking negatively was correlated with physical anhedonia and TAS-F3 (“externally oriented thinking”); 2) the IRI-F4 (“empathic concern”) is significantly negatively correlated to social anhedonia; 3) the IRI-F1(“personal distress”) lies in the center of these relationships. These results suggest an important role of alexithymia in schizotypy individuals’ empathic deficits, especially for empathy’s sub-component “personal distress”. Overall, network analysis has highlightedthe connections between sub-components of empathy and alexithymia, implying that alexithymia may serve as a potential intervention target for the empathy deficits in schizophrenia spectrum disorders.

Keyword阴性症状临床评估访谈 精神分裂症亚型 聚类分析
Document Type会议论文
Affiliation1.中国科学院心理研究所神经心理学与应用认知神经科学实验室, 中国科学院心理健康重点实验室(中国科学院心理研究所)
Recommended Citation
GB/T 7714
谢东杰,陈楚侨. 基于CAINS分类的不同精神分裂症亚型的表现异同[C],2018:611-612.
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