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Temporal Dynamics and Response Modulation across the Human Visual System in a Spatial Attention Task An ECoG Study
Martin, Anne B.1,9; Yang, Xiaofang2; Saalmann, Yuri B.1,10; Wang, Liang1,11; Shestyuk, Avgusta3; Lin, Jack J.5,6,7; Parvizi, Josef8; Knight, Robert T.3,4; Kastner, Sabine1,2
First AuthorMartin, Anne B.
2019-01-09
Source PublicationJOURNAL OF NEUROSCIENCE
Correspondent Emailppliang@cnu.edu.cn ; fuxl@psych.ac.cn
ISSN0270-6474
SubtypeArticle
Volume39Issue:2Pages:333-352
Abstract

The selection of behaviorally relevant information from cluttered visual scenes (often referred to as "attention") is mediated by a cortical large-scale network consisting of areas in occipital, temporal, parietal, and frontal cortex that is organized into a functional hierarchy of feedforward and feedback pathways. In the human brain, little is known about the temporal dynamics of attentional processing from studies at the mesoscopic level of electrocorticography (ECoG), that combines millisecond temporal resolution with precise anatomical localization of recording sites. We analyzed high-frequency broadband responses (HFB) responses from 626 electrodes implanted in 8 epilepsy patients who performed a spatial attention task. Electrode locations were reconstructed using a probabilistic atlas of the human visual system. HFB responses showed high spatial selectivity and tuning, constituting ECoG response fields (RFs), within and outside the topographic visual system. In accordance with monkey physiology studies, both RF widths and onset latencies increased systematically across the visual processing hierarchy. We used the spatial specificity of HFB responses to quantitatively study spatial attention effects and their temporal dynamics to probe a hierarchical top-down model suggesting that feedback signals back propagate the visual processing hierarchy. Consistent with such a model, the strengths of attentional modulation were found to be greater and modulation latencies to be shorter in posterior parietal cortex, middle temporal cortex and ventral extrastriate cortex compared with early visual cortex. However, inconsistent with such a model, attention effects were weaker and more delayed in anterior parietal and frontal cortex.

KeywordAttention Latencies Onset Latencies Spatial Response Fields Topographic Atlas
DOI10.1523/JNEUROSCI.1889-18.2018
Indexed BySCI
Language英语
Funding ProjectNational Institute of Mental Health Conte Center Grant[1P50MH109429] ; National Institute of Mental Health[R01MH064043] ; National Institute of Mental Health[R01MH109954] ; National Institute of Mental Health[R01MH110311] ; National Institute of Neurological Disorders and Stroke[R01R37NS21135] ; James S. McDonnell Foundation 21st Century Science Initiative, Understanding Human Cognition, collaborative Grant
WOS Research AreaNeurosciences & Neurology
WOS SubjectNeurosciences
WOS IDWOS:000455189900013
PublisherSOC NEUROSCIENCE
WOS KeywordPosterior Parietal Cortex ; Local-field Potentials ; Surface-based Analysis ; Cortical Areas V1 ; Neuronal Responses ; High-frequency ; Gamma-oscillations ; Electrical-stimulation ; Neural Mechanisms ; Macaque V1
Citation statistics
Document Type期刊论文
Identifierhttp://ir.psych.ac.cn/handle/311026/28105
Collection中国科学院心理健康重点实验室
Corresponding AuthorKastner, Sabine
Affiliation1.Princeton Univ, Princeton Neurosci Inst, Princeton, NJ 08544 USA
2.Princeton Univ, Dept Psychol, Princeton, NJ 08544 USA
3.Univ Calif Berkeley, Helen Wills Neurosci Inst, Berkeley, CA 94720 USA
4.Univ Calif Berkeley, Dept Psychol, Berkeley, CA 94720 USA
5.Univ Calif Irvine, Ctr Neurobiol Learning & Memory, Orange, CA 92868 USA
6.Univ Calif Irvine, Dept Biomed Engn, Orange, CA 92868 USA
7.Univ Calif Irvine, Dept Neurol, Orange, CA 92868 USA
8.Stanford Univ, Dept Neurol & Neurol Sci, Palo Alto, CA 94304 USA
9.CALTECH, Div Biol & Biol Engn, Pasadena, CA 91125 USA
10.Univ Wisconsin, Dept Psychol, Madison, WI 53706 USA
11.Chinese Acad Sci, Inst Psychol, CAS Key Lab Mental Hlth, Beijing 100101, Peoples R China
Recommended Citation
GB/T 7714
Martin, Anne B.,Yang, Xiaofang,Saalmann, Yuri B.,et al. Temporal Dynamics and Response Modulation across the Human Visual System in a Spatial Attention Task An ECoG Study[J]. JOURNAL OF NEUROSCIENCE,2019,39(2):333-352.
APA Martin, Anne B..,Yang, Xiaofang.,Saalmann, Yuri B..,Wang, Liang.,Shestyuk, Avgusta.,...&Kastner, Sabine.(2019).Temporal Dynamics and Response Modulation across the Human Visual System in a Spatial Attention Task An ECoG Study.JOURNAL OF NEUROSCIENCE,39(2),333-352.
MLA Martin, Anne B.,et al."Temporal Dynamics and Response Modulation across the Human Visual System in a Spatial Attention Task An ECoG Study".JOURNAL OF NEUROSCIENCE 39.2(2019):333-352.
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