Nostril-specific and structure-based olfactory learning of chiral discrimination in human adults

doi:10.7554/eLife.41296

	Nostril-specific and structure-based olfactory learning of chiral discrimination in human adults
	Feng, Guo 1,2,3; Zhou, Wen1,2
通讯作者	Zhou, Wen(zhouw@psych.ac.cn)
摘要	Practice makes perfect. In human olfaction, such plasticity is generally assumed to occur at the level of cortical synthetic processing that shares information from both nostrils. Here we present findings that challenge this view. In two experiments, we trained human adults unirhinally for the discrimination between odor enantiomers over a course of about 10 to 11 days. Results showed that training-induced perceptual gain was restricted to the trained nostril yet partially generalized to untrained odor enantiomers in a structure-rather than quality-based manner. In other words, learning enhanced the differentiation of chirality (molecular configuration) as opposed to overall odor quality (odor object) per se. These findings argue that, unlike earlier beliefs, one nostril does not readily know what the other learns. Moreover, the initial analytical processing of the structural features of uninarial olfactory input remains plastic in human adults.
	2019-01-17
语种	英语
DOI	10.7554/eLife.41296
发表期刊	ELIFE
ISSN	2050-084X
卷号	8 页码:12
收录类别	SCI ; SCI
资助项目	National Natural Science Foundation of China[31830037] ; Chinese Academy of Sciences[XDB32010200] ; Chinese Academy of Sciences[QYZDB-SSW-SMC055] ; National Natural Science Foundation of China[31422023] ; Chinese Academy of Sciences[QYZDB-SSW-SMC055] ; Chinese Academy of Sciences[XDB32010200] ; National Natural Science Foundation of China[31422023] ; National Natural Science Foundation of China[31830037]
出版者	ELIFE SCIENCES PUBLICATIONS LTD
WOS关键词	ODOR ; BULB ; REPRESENTATIONS ; PLASTICITY ; RAT ; CONNECTIONS
WOS研究方向	Life Sciences & Biomedicine - Other Topics
WOS类目	Biology
WOS记录号	WOS:000455876500001
资助机构	Chinese Academy of Sciences ; National Natural Science Foundation of China
引用统计	被引频次：6[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.psych.ac.cn/handle/311026/28114
专题	脑与认知科学国家重点实验室
通讯作者	Zhou, Wen
作者单位	1.Chinese Acad Sci, Inst Psychol, CAS Ctr Excellence Brain Sci & Intelligence Techn, State Key Lab Brain & Cognit Sci, Beijing, Peoples R China 2.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China 3.Southwest Jiaotong Univ, Psychol Res & Counseling Ctr, Chengdu, Sichuan, Peoples R China
第一作者单位	脑与认知科学国家重点实验室
通讯作者单位	脑与认知科学国家重点实验室
推荐引用方式 GB/T 7714	Feng, Guo,Zhou, Wen. Nostril-specific and structure-based olfactory learning of chiral discrimination in human adults[J]. ELIFE,2019,8:12.
APA	Feng, Guo,&Zhou, Wen.(2019).Nostril-specific and structure-based olfactory learning of chiral discrimination in human adults.ELIFE,8,12.
MLA	Feng, Guo,et al."Nostril-specific and structure-based olfactory learning of chiral discrimination in human adults".ELIFE 8(2019):12.

条目包含的文件
文件名称/大小	文献类型	版本类型	开放类型	使用许可
Nostril-specific and（663KB）	期刊论文	出版稿	限制开放	CC BY-NC-SA	请求全文