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Fundus examination of 199 851 newborns by digital imaging in China: a multicentre cross-sectional study | |
Tang, He1; Li, Na2; Li, Zhan3; Zhang, Meiju4; Wei, Meirong5; Huang, Changbing6![]() ![]() ![]() ![]() | |
First Author | He Tang |
Correspondent Email | wbbahu@ 163. com ; jinxi@ chinawch. org. cn ; nicgr@ 263. net |
Contribution Rank | 6 |
Abstract | Background The prevalence of ocular abnormalities of newborn in China has seldom been reported. To report the implementation of digital imaging in ocular screening of all newborns in multiple centres in China and to describe the abnormal findings of fundus examination, we did the cross-sectional study. Methods Fundus examinations were performed on newborns within the 42 days after birth using a RetCam wide-field digital imaging system. Digital images of the posterior pole, superior, nasal and temporal retinal fields of each participant were taken. All newborns were from eights centres across China from January 2009 to July 2017. Results A total of 199 851 newborns were included in the study. We detected 18 198 (9.11%) abnormal cases. The most frequent abnormality was severe retinal haemorrhage (RH) found in 12 810 cases (6.41%). The other anomalies included familial exudative vitreoretinopathy, retinopathy of prematurity, abnormal fundus pigmentation, subconjunctival haemorrhage, choroidal coloboma, idiopathic retinal venous tortuosity, exudative changes and other anomalies with uncertain identities. Conclusion This large-scale study of newborn fundus examination showed a relatively high prevalence of ocular abnormalities. Hundreds of neonates with rare disorders that severely impair ocular health were also detected at an early age. The long-term impact of other anomalies including RHs on the ocular system should be investigated by a perspective study. Our study suggested that fundus examination of newborns can play a beneficial role in ocular health. |
2018-12-01 | |
Language | 英语 |
DOI | 10.1136/bjophthalmol-2018-312366 |
Source Publication | BRITISH JOURNAL OF OPHTHALMOLOGY
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ISSN | 0007-1161 |
Volume | 102Issue:12Pages:1742-1746 |
Subtype | Article |
Indexed By | SCI |
Funding Project | National Infrastructure of Chinese Genetic Resources[YCZYPT[2017]01-6] ; National Key Research and Development Program of China[2016YFC1000307] ; National Science and Technology Basic Work[2014FY130100] ; National Science and Technology Basic Work[2014FY130100] ; National Key Research and Development Program of China[2016YFC1000307] ; National Infrastructure of Chinese Genetic Resources[YCZYPT[2017]01-6] |
Publisher | BMJ PUBLISHING GROUP |
WOS Keyword | Red-reflex ; Retinopathy ; Prematurity ; Sensitivity ; Specificity |
WOS Research Area | Ophthalmology |
WOS Subject | Ophthalmology |
WOS ID | WOS:000456552200025 |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.psych.ac.cn/handle/311026/28241 |
Collection | 中国科学院行为科学重点实验室 |
Corresponding Author | Ma, Xu; Jin, Xi; Wang, Binbin |
Affiliation | 1.Chinese Ctr Dis Control & Prevent, Natl Ctr Women & Childrens Hlth, Beijing, Peoples R China 2.Maternal & Childrens Hosp, Dept Ophthalmol, Kunming, Yunnan, Peoples R China 3.Maternal & Childrens Hosp, Dept Ophthalmol, Zhuhai, Guangdong, Peoples R China 4.Maternal & Childrens Hosp, Dept Ophthalmol, Linyi, Shandong, Peoples R China 5.Maternal & Childrens Hosp, Dept Ophthalmol, Liuzhou, Guangxi, Peoples R China 6.Chinese Acad Sci, Inst Psychol, Key Lab Behav Sci, Beijing, Peoples R China 7.Maternal & Childrens Hosp, Dept Ophthalmol, Hohhot, Inner Mongolia, Peoples R China 8.Maternal & Childrens Hosp, Dept Ophthalmol, Changchun, Jilin, Peoples R China 9.Maternal & Childrens Hosp, Dept Ophthalmol, Maanshan, Anhui, Peoples R China 10.Maternal & Childrens Hosp, Dept Ophthalmol, Urumqi, Xinjiang, Peoples R China 11.Chongqing Hlth Ctr Women & Children, Dept Ophthalmol, Chongqing, Peoples R China 12.Maternal & Childrens Hosp Hunan Prov, Dept Ophthalmol, Changsha, Hunan, Peoples R China 13.Maternal & Childrens Hosp, Dept Ophthalmol, Beijing, Peoples R China 14.Maternal & Childrens Hosp, Departmen Ophthalmol, Quanzhou, Fujian, Peoples R China 15.Natl Res Inst Family Planning, Beijing, Peoples R China |
Recommended Citation GB/T 7714 | Tang, He,Li, Na,Li, Zhan,et al. Fundus examination of 199 851 newborns by digital imaging in China: a multicentre cross-sectional study[J]. BRITISH JOURNAL OF OPHTHALMOLOGY,2018,102(12):1742-1746. |
APA | Tang, He.,Li, Na.,Li, Zhan.,Zhang, Meiju.,Wei, Meirong.,...&Wang, Binbin.(2018).Fundus examination of 199 851 newborns by digital imaging in China: a multicentre cross-sectional study.BRITISH JOURNAL OF OPHTHALMOLOGY,102(12),1742-1746. |
MLA | Tang, He,et al."Fundus examination of 199 851 newborns by digital imaging in China: a multicentre cross-sectional study".BRITISH JOURNAL OF OPHTHALMOLOGY 102.12(2018):1742-1746. |
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Fundus examination o(880KB) | 期刊论文 | 出版稿 | 限制开放 | CC BY-NC-SA | Application Full Text |
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