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Distinctive epileptogenic networks for parietal operculum seizures
Wang, Haixiang1,2; David, Olivier3,4; Zhou, Wenjing2; Wang, Liang5; Zhang, Bingqing2; Song, Xiancheng2; Lin, Jiuluan2; Bai, Jianjun2; Ruan, Jing2; Li, Jia2; Liu, Xiaoyan6; Wang, Qun1,7
First AuthorHaixiangWang
2019-02-01
Source PublicationEPILEPSY & BEHAVIOR
Correspondent Emailwangq@ccmu.edu.cn (q.wang)
ISSN1525-5050
SubtypeArticle
Volume91Pages:59-67
Contribution Rank5
Abstract

Objective: The present study investigated the electroclinical features and epileptogenic networks of parietal operculum seizures (POS) by using stereoelectroencephalography (SEEG) intracerebral recordings. Methods: Comprehensive presurgical evaluation data of seven patients with drug-resistant epilepsy with POS were analyzed retrospectively. Stereoelectroencephalography-recorded seizures were processed visually and quantitatively by using epileptogenicity mapping (EM), which has been proposed to ergonomically quantify the epileptogenicity of brain structures with a neuroimaging approach. Results: Six patients reported initial somatosensory or viscerosensitive symptoms. !dal clinical signs comprised frequently nocturnal hypermotor seizures and contralateral focal motor seizures, including tonic, tonic-clonic, or dystonic seizures of the face and limbs. lnterictal and ictal scalp EEG provided information regarding lateralization in the majority of patients, but the discharges were widely distributed over perisylvian or "rolandic-like" regions and the vertex. Furthermore, two subgroups of epileptogenic network organization were identified within POS by SEEG, visually and quantitatively, using an EM approach: group 1 (mesial frontal/dngulate networks) was observed in three patients who mainly exhibited hypermotor seizures; group 2 (perisylvian networks) was observed in four patients who mainly exhibited contralateral focal motor seizures. Conclusion: This study indicated that POS could be characterized by initial specific somatosensory sensations, followed by either frequently nocturnal hypermotor seizures or contralateral focal motor seizures. The distinctive seizure semiology depended on the organization of two primary epileptogenic networks. (C) 2018 Elsevier Inc. All rights reserved.

KeywordParietal epilepsy SEEG Epileptogenicity map Brain networks
DOI10.1016/j.yebeh.2018.08.031
Indexed BySCI
Language英语
Funding ProjectAgence Nationale de la Recherche[FORCE ANR-2013-TECS-0013-01] ; European Research Council under the European Union[16268 F-TRACT] ; Natural Science Foundation of China[81371631] ; Capital Health Research and Development of Special[2016-1-2011] ; Tsinghua University Initiative Scientific Research Programme[2015THZ01] ; Natural Science Foundation of China[31771255] ; Natural Science Foundation of China[81422024]
WOS Research AreaBehavioral Sciences ; Neurosciences & Neurology ; Psychiatry
WOS SubjectBehavioral Sciences ; Clinical Neurology ; Psychiatry
WOS IDWOS:000462155300011
PublisherACADEMIC PRESS INC ELSEVIER SCIENCE
WOS KeywordHYPERMOTOR SEIZURES ; LOBE EPILEPSY ; INSULAR LOBE ; ORIGIN ; CORTEX ; SEEG
Citation statistics
Document Type期刊论文
Identifierhttp://ir.psych.ac.cn/handle/311026/28832
Collection中国科学院心理健康重点实验室
Corresponding AuthorWang, Qun
Affiliation1.Capital Med Univ, Epilepsy Ctr, Dept Neurol, Beijing Tiantan Hosp, Beijing, Peoples R China
2.Tsinghua Univ, Epilepsy Ctr, Ynquan Hosp, Beijing, Peoples R China
3.Univ Grenoble Alpes, Grenoble Inst Neurosci, Grenoble, France
4.INSERM, U1216, Grenoble, France
5.Inst Psychol, CAS Key Lab Mental Hlth, Beijing, Peoples R China
6.Peking Univ, Dept Pediat, Hosp 1, Beijing, Peoples R China
7.China Natl Clin Res Ctr Neurol Dis, 6 Tiantan Xili, Beijing 100050, Peoples R China
Recommended Citation
GB/T 7714
Wang, Haixiang,David, Olivier,Zhou, Wenjing,et al. Distinctive epileptogenic networks for parietal operculum seizures[J]. EPILEPSY & BEHAVIOR,2019,91:59-67.
APA Wang, Haixiang.,David, Olivier.,Zhou, Wenjing.,Wang, Liang.,Zhang, Bingqing.,...&Wang, Qun.(2019).Distinctive epileptogenic networks for parietal operculum seizures.EPILEPSY & BEHAVIOR,91,59-67.
MLA Wang, Haixiang,et al."Distinctive epileptogenic networks for parietal operculum seizures".EPILEPSY & BEHAVIOR 91(2019):59-67.
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