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| Anti-Homer-3 antibody associated cerebellar ataxia: A rare case report and literature review | |
Xu, Xiaolu1,2; Ren, Haitao1,2; Li, Libo1,2; Wang, Jing3 ; Fechner, Kai4; Guan, Hongzhi1,2
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| Corresponding Author | Guan, Hongzhi(guanhz@263.net) |
| 2019-05-15 | |
| Source Publication | JOURNAL OF NEUROIMMUNOLOGY
 |
| ISSN | 0165-5728 |
| Volume | 330Pages:155-158 |
| Abstract | Anti-Homer-3 antibody associated cerebellar ataxia is a rare autoimmune cerebellar ataxia, which had been previously reported in 2 cases only. Here we present the third case where a middle-aged female experienced progressive cerebellar ataxia. A novel cerebellar ataxia antibody panel indicated sera of the patient was positive for anti-Homer-3 antibodies and established the diagnosis. Given steroids and long-term mycophenolate mofetil, the patient experienced partial improvement and remained stable in the follow-ups. Our report indicated immune-mediated causes should be considered in the context of 'idiopathic' cerebellar ataxia and immunotherapy could have therapeutic effects. |
| Keyword | Homer-3 antibody Cerebellar ataxia Autoimmune |
| DOI | 10.1016/j.jneuroim.2019.01.002 |
| Indexed By | SCI ; SCI |
| Language | 英语 |
| WOS Research Area | Immunology ; Neurosciences & Neurology |
| WOS Subject | Immunology ; Neurosciences |
| WOS ID | WOS:000465057100027 |
| Publisher | ELSEVIER SCIENCE BV |
| WOS Keyword | AUTOIMMUNITY |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.psych.ac.cn/handle/311026/28935 |
| Collection | 中国科学院心理健康重点实验室 |
| Corresponding Author | Guan, Hongzhi |
| Affiliation | 1.Peking Union Med Coll, Peking Union Med Coll Hosp, Dept Neurol, 1 Shuaifuyuan,Wangfujing St, Beijing 100730, Peoples R China 2.Chinese Acad Med Sci, 1 Shuaifuyuan,Wangfujing St, Beijing 100730, Peoples R China 3.Chinese Acad Sci, Dept Psychol, Inst Psychol, CAS Key Lab Mental Hlth, Beijing, Peoples R China 4.Euroimmun AG, Inst Expt Immunol, Lubeck, Germany |
| Recommended Citation GB/T 7714 | Xu, Xiaolu,Ren, Haitao,Li, Libo,et al. Anti-Homer-3 antibody associated cerebellar ataxia: A rare case report and literature review[J]. JOURNAL OF NEUROIMMUNOLOGY,2019,330:155-158. |
| APA | Xu, Xiaolu,Ren, Haitao,Li, Libo,Wang, Jing,Fechner, Kai,&Guan, Hongzhi.(2019).Anti-Homer-3 antibody associated cerebellar ataxia: A rare case report and literature review.JOURNAL OF NEUROIMMUNOLOGY,330,155-158. |
| MLA | Xu, Xiaolu,et al."Anti-Homer-3 antibody associated cerebellar ataxia: A rare case report and literature review".JOURNAL OF NEUROIMMUNOLOGY 330(2019):155-158. |
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