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Anti-Homer-3 antibody associated cerebellar ataxia: A rare case report and literature review | |
Xu, Xiaolu1; Ren, Haitao1; Li, Libo1; Wang, Jing2![]() | |
第一作者 | Xu, Xiaolu |
通讯作者邮箱 | h. guan(guanhz@263.net) |
心理所单位排序 | 2 |
摘要 | Anti-Homer-3 antibody associated cerebellar ataxia is a rare autoimmune cerebellar ataxia, which had been previously reported in 2 cases only. Here we present the third case where a middle-aged female experienced progressive cerebellar ataxia. A novel cerebellar ataxia antibody panel indicated sera of the patient was positive for anti-Homer-3 antibodies and established the diagnosis. Given steroids and long-term mycophenolate mofetil, the patient experienced partial improvement and remained stable in the follow-ups. Our report indicated immune-mediated causes should be considered in the context of 'idiopathic' cerebellar ataxia and immunotherapy could have therapeutic effects. |
关键词 | Homer-3 antibody Cerebellar ataxia Autoimmune |
2019-05-15 | |
语种 | 英语 |
DOI | 10.1016/j.jneuroim.2019.01.002 |
发表期刊 | JOURNAL OF NEUROIMMUNOLOGY
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ISSN | 0165-5728 |
卷号 | 330页码:155-158 |
期刊论文类型 | article |
收录类别 | SCI |
出版者 | ELSEVIER SCIENCE BV |
WOS关键词 | AUTOIMMUNITY |
WOS研究方向 | Immunology ; Neurosciences & Neurology |
WOS类目 | Immunology ; Neurosciences |
WOS记录号 | WOS:000465057100027 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | https://ir.psych.ac.cn/handle/311026/28935 |
专题 | 中国科学院心理健康重点实验室 |
通讯作者 | Guan, Hongzhi |
作者单位 | 1.Department of Neurology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China 2.CAS Key Laboratory of Mental Health, Institute of Psychology, Department of Psychology, Chinese Academy of Sciences, Beijing, China 3.Institute of Experimental Immunology, Affiliated to Euroimmun AG, Lübeck, Germany |
推荐引用方式 GB/T 7714 | Xu, Xiaolu,Ren, Haitao,Li, Libo,et al. Anti-Homer-3 antibody associated cerebellar ataxia: A rare case report and literature review[J]. JOURNAL OF NEUROIMMUNOLOGY,2019,330:155-158. |
APA | Xu, Xiaolu,Ren, Haitao,Li, Libo,Wang, Jing,Fechner, Kai,&Guan, Hongzhi.(2019).Anti-Homer-3 antibody associated cerebellar ataxia: A rare case report and literature review.JOURNAL OF NEUROIMMUNOLOGY,330,155-158. |
MLA | Xu, Xiaolu,et al."Anti-Homer-3 antibody associated cerebellar ataxia: A rare case report and literature review".JOURNAL OF NEUROIMMUNOLOGY 330(2019):155-158. |
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Anti-Homer-3 antibod(851KB) | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | 浏览 下载 |
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