The prevalence, metabolic disturbances and clinical correlates of recent suicide attempts in Chinese inpatients with major depressive disorder | |
Ma, Yue-Jiao1; Wang, Dong-Fang2; Yuan, Ming1; Zhang, Xiao-Jie1; Long, Jiang1; Chen, Shu-Bao1; Wu, Qiu-Xia1; Wang, Xu-Yi1; Patel, Marguerite3; Verrico, Christopher D.3; Liu, Tie-Qiao1; Zhang, Xiang-Yang4,5 | |
第一作者 | Ma, Yue-Jiao |
通讯作者邮箱 | liutieqiao123@csu.edu.cn ; xiang.y.zhang@uth.tmc.edu ; zhangxy9@gmail.com |
摘要 | BackgroundMetabolic disturbances have been correlated with suicidality, but little is known about the association between suicide risk and metabolic disturbances among individuals with depression. This study was to evaluate the prevalence and clinical correlations, especially cardio-metabolic associated factors of recent suicide attempts in Chinese patients with major depressive disorder (MDD).MethodsA total of 288 MDD inpatients were recruited. Their clinical and demographic data together with plasma glucose, lipid and thyroid function parameters were collected. Self-Rating Depression Scale (SDS), Self-Rating Anxiety Scale (SAS) and Eysenck Personality Questionnaire (EPQ) were rated for most of the patients.ResultsOf these MDD inpatients, 20.14% had attempted suicide during the past 1 month. Compared to those who had not attempted suicide, the suicide attempters had a significantly longer duration of illness, lower low-density lipoprotein (LDL) cholesterol, lower total cholesterol, and more psychotic symptoms. However, all these significant results did not survive after the bonferroni correction (all p>0.05). A logistic regression analysis indicated that suicide attempts were associated with the lower total cholesterol and more psychotic symptoms.ConclusionsOur findings support the hypothesis of the association of low plasma cholesterol level and recent suicidal attempts in patients with MDD. |
关键词 | Depression Suicide attempt Prevalence Clinical correlates Metabolic disturbance |
2019-05-10 | |
语种 | 英语 |
DOI | 10.1186/s12888-019-2131-6 |
发表期刊 | BMC PSYCHIATRY |
ISSN | 1471-244X |
卷号 | 19页码:7 |
期刊论文类型 | article |
收录类别 | SCI |
资助项目 | National Key R&D Program of China[2017YFC1310400] ; National Natural Science Foundation of China[81371465] ; National Natural Science Foundation of China[81671324] |
出版者 | BMC |
WOS关键词 | LOW SERUM-CHOLESTEROL ; CENTRAL SEROTONERGIC ACTIVITY ; BODY-MASS INDEX ; LIPID PROFILE ; RISK ; IDEATION ; ASSOCIATION ; BEHAVIOR ; BIPOLAR ; INDIVIDUALS |
WOS研究方向 | Psychiatry |
WOS类目 | Psychiatry |
WOS记录号 | WOS:000467602800001 |
资助机构 | National Key R&D Program of China ; National Natural Science Foundation of China |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.psych.ac.cn/handle/311026/29114 |
专题 | 健康与遗传心理学研究室 |
通讯作者 | Liu, Tie-Qiao; Zhang, Xiang-Yang |
作者单位 | 1.Cent S Univ, China Natl Clin Res Ctr Mental Hlth Disorders, Key Lab Psychiat & Mental Hlth Hunan Prov, Xiangya Hosp 2,Dept Psychiat,Chinese Natl Technol, 139 Middle Renmin Rd, Changsha 410011, Hunan, Peoples R China 2.Cent S Univ, Psychosomat Hlth Inst, Xiangya Hosp 3, Changsha, Hunan, Peoples R China 3.Baylor Coll Med, Dept Psychiat & Behav Sci, Houston, TX 77030 USA 4.Chinese Acad Sci, Inst Psychol, Beijing, Peoples R China 5.Univ Texas Hlth Sci Ctr Houston, Dept Psychiat & Behav Sci, 1941 East Rd, Houston, TX 77054 USA |
通讯作者单位 | 中国科学院心理研究所 |
推荐引用方式 GB/T 7714 | Ma, Yue-Jiao,Wang, Dong-Fang,Yuan, Ming,et al. The prevalence, metabolic disturbances and clinical correlates of recent suicide attempts in Chinese inpatients with major depressive disorder[J]. BMC PSYCHIATRY,2019,19:7. |
APA | Ma, Yue-Jiao.,Wang, Dong-Fang.,Yuan, Ming.,Zhang, Xiao-Jie.,Long, Jiang.,...&Zhang, Xiang-Yang.(2019).The prevalence, metabolic disturbances and clinical correlates of recent suicide attempts in Chinese inpatients with major depressive disorder.BMC PSYCHIATRY,19,7. |
MLA | Ma, Yue-Jiao,et al."The prevalence, metabolic disturbances and clinical correlates of recent suicide attempts in Chinese inpatients with major depressive disorder".BMC PSYCHIATRY 19(2019):7. |
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