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Alternative TitleBilateral insular functional connectivity in epilepsy patients:A cortico-cortical evoked potential study
张冰清; 王亮; 王海祥; 阮静; 李佳; 周文静
First Author张冰清
Contribution Rank2
Other AbstractObjective To explore bilateral insular functional connectivity in refractory epilepsy patients using electrical cortical stimulation by stereoelectroencephalography (SEEG)electrodes.Methods We retrospectively analyzed the clinical data of 4 patients with insular or insular-related drug resistant epilepsy at Epilepsy Center of Yuquan Hospital of Tsinghua University from January 2014 to August 2016. Four patients were implanted with SEEG electrodes in bilateral insular lobes for cortical electrical stimulation.The evoked potential response of each contact was determined by visual analysis and nonparametric test.The evoked potential response was recorded at the contralateral insular lobe electrode on the stimulating side,and the response rate and anatomical distribution were determined.Results A total of 28SEEG electrodes (98 contacts)were implanted into the insular lobe in 4patients,of which 12 electrodes (47 contacts )were implanted into the left insular lobe.Cortical-cortical evoked potential (CCEP)responses were found between bilateral insular lobes in 4 patients,and bomotopic bidirectional CCEP connections were found between bilateral insular lobes.The response rate of contralateral insular CCEP was 39.8%,and the peak latency was 15.5-196.0ms.There were bi-directional CCEP connections between corresponding bilateral insular gyri.Conclusions There are bi-directional functional connections between bilateral insular lobes in patients with insular or insular-related epilepsy, particularly in patients with post-viral encephalitis epilepsy.However,more studies are needed to confirm this result.
Keyword癫痫 岛叶 立体脑电图 皮质电刺激 皮质-皮质诱发电位
Source Publication中华神经外科杂志
Project Intro.清华大学自主科研计划(20161080074).
Document Type期刊论文
Recommended Citation
GB/T 7714
张冰清,王亮,王海祥,等. 基于癫痫患者皮质-皮质诱发电位的双侧岛叶功能连接研究(附四例报告)[J]. 中华神经外科杂志,2018,34(12):6.
APA 张冰清,王亮,王海祥,阮静,李佳,&周文静.(2018).基于癫痫患者皮质-皮质诱发电位的双侧岛叶功能连接研究(附四例报告).中华神经外科杂志,34(12),6.
MLA 张冰清,et al."基于癫痫患者皮质-皮质诱发电位的双侧岛叶功能连接研究(附四例报告)".中华神经外科杂志 34.12(2018):6.
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