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Lifespan normative data on rates of brain volume changes | |
Battaglini, Marco1; Gentile, Giordano1; Luchetti, Ludovico1; Giorgio, Antonio1; Vrenken, Hugo2; Barkhof, Frederik2,3,4,5; Cover, Keith S.2,6; Bakshi, Rohit7; Chu, Renxin7; Sormani, Maria Pia8; Enzinger, Christian9,10; Ropele, Stefan9; Ciccarelli, Olga5,11; Wheeler-Kingshott, Claudia11,12,13; Yiannakas, Marios11; Filippi, Massimo14; Rocca, Maria Assunta14; Preziosa, Paolo14; Gallo, Antonio15; Bisecco, Alvino15; Palace, Jacqueline16; Kong, Yazhuo17,18; Horakova, Dana19,20,21; Vaneckova, Manuela21,22; Gasperini, Claudio23; Ruggieri, Serena23; De Stefano, Nicola1 | |
第一作者 | Marco Battaglini |
通讯作者邮箱 | destefano@unisi.it (n. de stefano) |
摘要 | We provide here normative values of yearly percentage brain volume change (PBVC/y) as obtained with Structural Imaging Evaluation, using Normalization, of Atrophy, a widely used open-source software, developing a PBVC/y calculator for assessing the deviation from the expected PBVC/y in patients with neurological disorders. We assessed multicenter (34 centers, 11 acquisition protocols) magnetic resonance imaging data of 720 healthy participants covering the whole adult lifespan (16-90 years). Data of 421 participants with a follow-up > 6 months were used to obtain the normative values for PBVC/y and data of 392 participants with a follow-up <1 month were selected to assess the intrasubject variability of the brain volume measurement. A mixed model evaluated PBVC/y dependence on age, sex, and magnetic resonance imaging parameters (scan vendor and magnetic field strength). PBVC/y was associated with age (p < 0.001), with 60- to 70-year-old participants showing twice more volume decrease than participants aged 30-40 years. PBVC/y was also associated with magnetic field strength, with higher decreases when measured by 1.5T than 3T scanners (p < 0.001). The variability of PBVC/y normative percentiles was narrower as the interscan interval was longer (e.g., 80th normative percentile was 50% smaller for participants with 2-year than with 1-year follow-up). The use of these normative data, eased by the freely available calculator, might help in better discriminating pathological from physiological conditions in the clinical setting. (C) 2019 Published by Elsevier Inc. |
关键词 | Normative data Atrophy Aging MRI Brain volume |
2019-09-01 | |
语种 | 英语 |
DOI | 10.1016/j.neurobiolaging.2019.05.010 |
发表期刊 | NEUROBIOLOGY OF AGING |
ISSN | 0197-4580 |
卷号 | 81页码:30-37 |
期刊论文类型 | article |
收录类别 | SCI |
资助项目 | National Institute for Health Research University College London Hospitals Biomedical Research Centre, UK |
出版者 | ELSEVIER SCIENCE INC |
WOS关键词 | CLINICAL-RELEVANCE ; ATROPHY ; MRI ; DIAGNOSIS ; ROBUST ; GRAY |
WOS研究方向 | Geriatrics & Gerontology ; Neurosciences & Neurology |
WOS类目 | Geriatrics & Gerontology ; Neurosciences |
WOS记录号 | WOS:000484435300004 |
资助机构 | National Institute for Health Research University College London Hospitals Biomedical Research Centre, UK |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.psych.ac.cn/handle/311026/29815 |
专题 | 中国科学院行为科学重点实验室 |
通讯作者 | De Stefano, Nicola |
作者单位 | 1.Univ Siena, Dept Med Surg & Neurosci, Viale Bracci 2, I-53100 Siena, Italy 2.MS Ctr Amsterdam, Dept Radiol & Nucl Med, Amsterdam, Netherlands 3.UCL London, Inst Neurol, London, England 4.UCL London, Inst Healthcare Engn, London, England 5.UCLH, BRC, NIHR, London, England 6.Vrije Univ Amsterdam, Dept Phys & Med Technol, Med Ctr, Amsterdam, Netherlands 7.Harvard Med Sch, Brigham & Womens Hosp, Ann Romney Ctr Neurol Dis, Lab Neuroimaging Res, Boston, MA 02115 USA 8.Univ Genoa, Dept Hlth Sci DISSAL, Genoa, Italy 9.Med Univ Graz, Dept Neurol, Graz, Austria 10.Med Univ Graz, Dept Radiol, Div Neuroradiol Vasc & Intervent Radiol, Graz, Austria 11.UCL, UCL Inst Neurol, Queen Sq Multiple Sclerosis Ctr, London, England 12.C Mondino Natl Neurol Inst, UK Res Ctr, Brain MRI 3T, Pavia, Italy 13.Univ Pavia, Dept Brain & Behav Sci, Pavia, Italy 14.Univ Vita Salute San Raffaele, San Raffaele Sci Inst, Div Neurosci, Neuroimaging Res Unit,Inst Expt Neurol, Milan, Italy 15.Univ Campania Luigi Vanvitelli, Dept Med Surg Neurol Metab & Aging Sci, Naples, Italy 16.Univ Oxford, Oxford Univ Hosp NHS Trust, Nuffield Dept Clin Neurosci, Oxford, England 17.Inst Psychol, CAS Key Lab Behav Sci, Beijing, Peoples R China 18.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China 19.Charles Univ Prague, Fac Med 1, Dept Neurol, Prague, Czech Republic 20.Charles Univ Prague, Fac Med 1, Ctr Clin Neurosci, Prague, Czech Republic 21.Gen Univ Hosp Prague, Prague, Czech Republic 22.Charles Univ Prague, Fac Med 1, Dept Radiodiagnost, Prague, Czech Republic 23.S Camillo Forlanini Hosp, Dept Neurosci, Rome, Italy |
推荐引用方式 GB/T 7714 | Battaglini, Marco,Gentile, Giordano,Luchetti, Ludovico,et al. Lifespan normative data on rates of brain volume changes[J]. NEUROBIOLOGY OF AGING,2019,81:30-37. |
APA | Battaglini, Marco.,Gentile, Giordano.,Luchetti, Ludovico.,Giorgio, Antonio.,Vrenken, Hugo.,...&De Stefano, Nicola.(2019).Lifespan normative data on rates of brain volume changes.NEUROBIOLOGY OF AGING,81,30-37. |
MLA | Battaglini, Marco,et al."Lifespan normative data on rates of brain volume changes".NEUROBIOLOGY OF AGING 81(2019):30-37. |
条目包含的文件 | ||||||
文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
Lifespan normative d(691KB) | 期刊论文 | 出版稿 | 限制开放 | CC BY-NC-SA | 请求全文 |
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