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成瘾药物心理依赖及复发的脑机制研究
Alternative TitleThe Brain Mechanisms of Psychological Dependence and Relapse of Abusive Drugs
郑希耕; 李勇辉; 隋南
2006
Source Publication心理科学进展
ISSN1671-3710
Volume14Issue:4Pages:522-531
Abstract围绕学习、记忆、情绪及应激等心理因素与复发的关系,应用阿片类物质心理依赖研究条件性位置偏爱,条件性位置厌恶,Morris水迷宫量化觅药动机模型,行为及条件性行为敏感化等多种动物行为模型,从情绪相关学习、记忆在成瘾行为中的作用,不同神经核团与神经递质系统活动性的改变,应激相关因素易化的成瘾易感性,自然奖赏与成瘾药物奖赏相关记忆的比较研究等方面,对应激与记忆相关的吗啡心理依赖及复发的脑机制进行了系列研究。
Keyword学习记忆 应激 心理依赖 成瘾易感性 觅药动机 自然奖赏
Subject Area生理心理学/生物心理学 ; 认知神经科学 ; 医学心理学
Indexed By中文核心期刊要目总览 ASPT来源刊 CJFD收录刊
Language中文
Funding Project国家重点基础研究发展计划(2003CB515404),国家自 然科学基金(30230130,30470578)资助项目。
NoteThis project focuses on investigations of the brain mechanisms of the psychological dependence of abusive drugs. By using various animal models, such as conditioned place preference (CPP), conditioned place aversion (CPA), drug-seeking intensity gradation model of Morris water maze, behavioral and conditioned behavioral sensitization, the roles of environmental stress, positive and negative emotional states on psychological dependence and its relapse, neural mechanism comparisons between drug reward and natural reward were explored from behavioral to neuronal and genetic level.
Document Type期刊论文
Identifierhttp://ir.psych.ac.cn/handle/311026/3042
Collection中国科学院心理研究所回溯数据库(1956-2010)
Corresponding Author隋南
Recommended Citation
GB/T 7714
郑希耕,李勇辉,隋南. 成瘾药物心理依赖及复发的脑机制研究[J]. 心理科学进展,2006,14(4):522-531.
APA 郑希耕,李勇辉,&隋南.(2006).成瘾药物心理依赖及复发的脑机制研究.心理科学进展,14(4),522-531.
MLA 郑希耕,et al."成瘾药物心理依赖及复发的脑机制研究".心理科学进展 14.4(2006):522-531.
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