Institutional Repository of Key Laboratory of Behavioral Science, CAS
Rumination and the default mode network: Meta-analysis of brain imaging studies and implications for depression | |
Zhou, Hui-Xia1,2,3; Chen, Xiao1,2,3; Shen, Yang-Qian1; Li, Le1,2,3; Chen, Ning-Xuan1,2,3; Zhu, Zhi-Chen1,2,3; Castellanos, Francisco Xavier5,6; Yan, Chao-Gan1,2,3,4,5 | |
第一作者 | Zhou, Hui-Xia |
通讯作者邮箱 | yancg@psych.ac.cn |
心理所单位排序 | 1 |
摘要 | Rumination is strongly and consistently correlated with depression. Although multiple studies have explored the neural correlates of rumination, findings have been inconsistent and the mechanisms underlying rumination remain elusive. Functional brain imaging studies have identified areas in the default mode network (DMN) that appear to be critically involved in ruminative processes. However, a meta-analysis to synthesize the findings of brain regions underlying rumination is currently lacking. Here, we conducted a meta-analysis consisting of experimental tasks that investigate rumination by using Signed Differential Mapping of 14 fMRI studies comprising 286 healthy participants. Furthermore, rather than treat the DMN as a unitary network, we examined the contribution of three DMN subsystems to rumination. Results confirm the suspected association between rumination and DMN activation, specifically implicating the DMN core regions and the dorsal medial prefrontal cortex subsystem. Based on these findings, we suggest a hypothesis of how DMN regions support rumination and present the implications of this model for treating major depressive disorder characterized by rumination. |
关键词 | Rumination Depression Default mode network Core regions Dorsal medial prefrontal cortex subsystem |
2020-02-01 | |
语种 | 英语 |
DOI | 10.1016/j.neuroimage.2019.116287 |
发表期刊 | NEUROIMAGE |
ISSN | 1053-8119 |
卷号 | 206页码:9 |
期刊论文类型 | article |
收录类别 | SCI |
资助项目 | National Key R&D Program of China[2017YFC1309902] ; National Natural Science Foundation of China[81671774] ; National Natural Science Foundation of China[81630031] ; 13th Five-year Informatization Plan of Chinese Academy of Sciences[XXH13505] |
出版者 | ACADEMIC PRESS INC ELSEVIER SCIENCE |
WOS关键词 | SELF-FOCUS ; AUTOBIOGRAPHICAL MEMORY ; DISORDER ; FUTURE ; JUDGMENTS ; SYMPTOMS ; SEARCH ; MATTER |
WOS研究方向 | Neurosciences & Neurology ; Radiology, Nuclear Medicine & Medical Imaging |
WOS类目 | Neurosciences ; Neuroimaging ; Radiology, Nuclear Medicine & Medical Imaging |
WOS记录号 | WOS:000507987000038 |
Q分类 | Q1 |
资助机构 | National Key R&D Program of China ; National Natural Science Foundation of China ; 13th Five-year Informatization Plan of Chinese Academy of Sciences |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.psych.ac.cn/handle/311026/30676 |
专题 | 中国科学院行为科学重点实验室 |
通讯作者 | Yan, Chao-Gan |
作者单位 | 1.Chinese Acad Sci, Inst Psychol, Key Lab Behav Sci, Beijing, Peoples R China 2.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China 3.Chinese Acad Sci, Inst Psychol, Int Big Data Ctr Depress Res, Beijing, Peoples R China 4.Chinese Acad Sci, Inst Psychol, Magnet Resonance Imaging Res Ctr, Beijing, Peoples R China 5.NYU Langone, Hassenfeld Childrens Hosp, Dept Child & Adolescent Psychiat, New York, NY USA 6.Nathan S Kline Inst Psychiat Res, Orangeburg, NY USA |
第一作者单位 | 中国科学院行为科学重点实验室 |
通讯作者单位 | 中国科学院行为科学重点实验室; 管理支撑系统 |
推荐引用方式 GB/T 7714 | Zhou, Hui-Xia,Chen, Xiao,Shen, Yang-Qian,et al. Rumination and the default mode network: Meta-analysis of brain imaging studies and implications for depression[J]. NEUROIMAGE,2020,206:9. |
APA | Zhou, Hui-Xia.,Chen, Xiao.,Shen, Yang-Qian.,Li, Le.,Chen, Ning-Xuan.,...&Yan, Chao-Gan.(2020).Rumination and the default mode network: Meta-analysis of brain imaging studies and implications for depression.NEUROIMAGE,206,9. |
MLA | Zhou, Hui-Xia,et al."Rumination and the default mode network: Meta-analysis of brain imaging studies and implications for depression".NEUROIMAGE 206(2020):9. |
条目包含的文件 | ||||||
文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
2019Neuroimage.pdf(1481KB) | 期刊论文 | 作者接受稿 | 限制开放 | CC BY-NC-SA | 请求全文 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论