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Effort-cost computation in a transdiagnostic psychiatric sample: Differences among patients with schizophrenia, bipolar disorder, and major depressive disorder
Zou, Ying-Min1,2; Ni, Ke1,2,3; Wang, Yan-Yu1,2,4; Yu, En-Qing3; Lui, Simon S. Y.1,5; Zhou, Fu-Chun6; Yang, Han-Xue1,2; Cohen, Alex S.7; Strauss, Gregory P.8; Cheung, Eric F. C.5; Chan, Raymond C. K.1,2
第一作者Zou, Ying-Min
通讯作者邮箱rckchan@psych.ac.cn
心理所单位排序1
摘要

Amotivational symptoms are observed in schizophrenia (SCZ), bipolar disorder (BD), and major depressive disorder (MDD). Effort-cost computation may be a potential contributor to amotivation transdiagnostically. This study examined effort-cost computation in these three diagnostic groups. This study recruited 141 outpatients (49 SCZ, 52 non-psychotic BD, and 40 non-psychotic MDD) and 57 healthy controls (HCs). We administered the Effort-Expenditure for Reward Task (EEfRT), which manipulated different levels of reward magnitude and probability relating to a high and low physical effort task. There were significant interactions between group and reward magnitude, group and reward probability, and group and expected value on the percentage of high-effort choices. SCZ, BD, and MDD patients made comparably fewer high-effort choices than HCs in the high-reward magnitude, high-reward probability, and high-expected-value conditions. Self-reported amotivation did not correlate with decision-making on the EEfRT. Our findings suggest that reduced effort expenditure for reward is a transdiagnostic phenotype in SCZ, BD, and MDD.

2019-11-06
语种英语
DOI10.1002/pchj.316
发表期刊PSYCH JOURNAL
ISSN2046-0252
页码13
期刊论文类型article
收录类别SCI
资助项目National Science Fund China[81571317] ; Beijing Municipal Science & Technology Commission[Z161100000216138] ; Beijing Training Project for the Leading Talents in Science and Technology[Z151100000315020] ; CAS Key Laboratory of Mental Health, Institute of Psychology
出版者WILEY
WOS关键词DECISION-MAKING PARADIGMS ; NEGATIVE SYMPTOMS ; EFFORT ALLOCATION ; I-DISORDER ; MOTIVATION DEFICITS ; EFFORT EXPENDITURE ; MOOD STABILIZER ; CLINICAL-TRIALS ; RATING-SCALE ; REWARD
WOS研究方向Psychology
WOS类目Psychology, Multidisciplinary
WOS记录号WOS:000494550700001
资助机构National Science Fund China ; Beijing Municipal Science & Technology Commission ; Beijing Training Project for the Leading Talents in Science and Technology ; CAS Key Laboratory of Mental Health, Institute of Psychology
引用统计
被引频次:32[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.psych.ac.cn/handle/311026/30728
专题中国科学院心理健康重点实验室
通讯作者Chan, Raymond C. K.
作者单位1.Inst Psychol, Neuropsychol & Appl Cognit Neurosci Lab, CAS Key Lab Mental Hlth, Beijing, Peoples R China
2.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China
3.Qiqihar Psychiat Hosp, Qiqihar, Heilongjiang, Peoples R China
4.Weifang Med Univ, Dept Psychol, Weifang, Peoples R China
5.Castle Peak Hosp, Hong Kong, Peoples R China
6.Capital Med Univ, Beijing Anding Hosp, Beijing Key Lab Mental Disorders, Beijing, Peoples R China
7.Louisiana State Univ, Dept Psychol, Baton Rouge, LA 70803 USA
8.Univ Georgia, Dept Psychol, Athens, GA 30602 USA
第一作者单位认知与发展心理学研究室
通讯作者单位认知与发展心理学研究室
推荐引用方式
GB/T 7714
Zou, Ying-Min,Ni, Ke,Wang, Yan-Yu,et al. Effort-cost computation in a transdiagnostic psychiatric sample: Differences among patients with schizophrenia, bipolar disorder, and major depressive disorder[J]. PSYCH JOURNAL,2019:13.
APA Zou, Ying-Min.,Ni, Ke.,Wang, Yan-Yu.,Yu, En-Qing.,Lui, Simon S. Y..,...&Chan, Raymond C. K..(2019).Effort-cost computation in a transdiagnostic psychiatric sample: Differences among patients with schizophrenia, bipolar disorder, and major depressive disorder.PSYCH JOURNAL,13.
MLA Zou, Ying-Min,et al."Effort-cost computation in a transdiagnostic psychiatric sample: Differences among patients with schizophrenia, bipolar disorder, and major depressive disorder".PSYCH JOURNAL (2019):13.
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