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Differential profiles of response inhibition deficit between male children with autism spectrum disorders and schizophrenia
Shi, Li-juan1,2; Zhou, Han-yu1,3; Shen, Yan-mei4; Wang, Ya1,3; Fang, Yu-min4; He, Yu-qiong4; Ou, Jian-jun4; Luo, Xue-rong4; Cheung, Eric F. C.5; Chan, Raymond C. K.1,3
First AuthorShi, Li-juan
Correspondent Emailrckchan@psych.ac.cn
2019-10-27
Source PublicationAUTISM RESEARCH
ISSN1939-3792
SubtypeArticle
Pages12
Contribution Rank1
Abstract

Autism spectrum disorders (ASD) and schizophrenia (SZ) are both associated with response inhibition impairment. However, the relative pattern of deficits in these two disorders remains unclear. Twenty-three male children with ASD, 23 male children with SZ, and 32 typically developing male controls were recruited to complete a set of tasks measuring response inhibition in the visual, auditory, and verbal domains. We found that visual, auditory, and verbal response inhibitions were impaired in both children with ASD and children with SZ. Compared with typically developing controls, children with ASD made more commission errors whereas children with SZ responded much slower in the visual response inhibition task. Both clinical groups showed comparable impairment in verbal response inhibition, but children with SZ were more impaired in auditory response inhibition than children with ASD. These different patterns of response inhibition deficit between male children with ASD and SZ may help to differentiate between these two disorders and may be potential targets for intervention. Autism Res 2019, 00: 1-8. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. Lay Summary In this study, we found that male children with autism spectrum disorder (ASD) made more commission errors whereas male children with schizophrenia (SZ) responded much slower in the visual response inhibition task. Both clinical groups exhibited comparable impairments in verbal response inhibition, but male children with SZ were more impaired in auditory response inhibition than male children with ASD. Our findings provide potential targets for intervention.

Keywordautism spectrum disorder schizophrenia response inhibition visual auditory verbal
DOI10.1002/aur.2231
Indexed BySCI
Language英语
Funding OrganizationNational Key Research and Development Programme ; China Postdoctoral Science Foundation ; Humanity and Social Science Youth Foundation of the Ministry of Education ; CAS Key Laboratory of Mental Health, Institute of Psychology
Funding ProjectNational Key Research and Development Programme[2016YFC0906402] ; China Postdoctoral Science Foundation[2016 M601157] ; Humanity and Social Science Youth Foundation of the Ministry of Education[17YJC190022] ; CAS Key Laboratory of Mental Health, Institute of Psychology
WOS Research AreaBehavioral Sciences ; Psychology
WOS SubjectBehavioral Sciences ; Psychology, Developmental
WOS IDWOS:000492701500001
PublisherWILEY
WOS KeywordCHILDHOOD-ONSET SCHIZOPHRENIA ; EXECUTIVE FUNCTION ; INTERFERENCE CONTROL ; SUSTAINED ATTENTION ; TASK ; DYSFUNCTION ; IMPAIRMENT ; ADULTS ; SAMPLE ; INDIVIDUALS
Citation statistics
Cited Times:2[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.psych.ac.cn/handle/311026/30792
Collection中国科学院心理健康重点实验室
Corresponding AuthorChan, Raymond C. K.
Affiliation1.Chinese Acad Sci, Inst Psychol, CAS Key Lab Mental Hlth, Neuropsychol & Appl Cognit Neurosci Lab, Beijing, Peoples R China
2.Hunan Univ Sci & Technol, Sch Educ, Xiangtan, Hunan, Peoples R China
3.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China
4.Cent S Univ, Xiangya Hosp 2, Mental Hlth Inst, Changsha, Hunan, Peoples R China
5.Castle Peak Hosp, Hong Kong, Peoples R China
First Author Affilication认知与发展心理学研究室
Corresponding Author Affilication认知与发展心理学研究室
Recommended Citation
GB/T 7714
Shi, Li-juan,Zhou, Han-yu,Shen, Yan-mei,et al. Differential profiles of response inhibition deficit between male children with autism spectrum disorders and schizophrenia[J]. AUTISM RESEARCH,2019:12.
APA Shi, Li-juan.,Zhou, Han-yu.,Shen, Yan-mei.,Wang, Ya.,Fang, Yu-min.,...&Chan, Raymond C. K..(2019).Differential profiles of response inhibition deficit between male children with autism spectrum disorders and schizophrenia.AUTISM RESEARCH,12.
MLA Shi, Li-juan,et al."Differential profiles of response inhibition deficit between male children with autism spectrum disorders and schizophrenia".AUTISM RESEARCH (2019):12.
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