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The left inferior longitudinal fasciculus supports orthographic processing: Evidence from a lesion-behavior mapping analysis | |
Wang, Ke1,2; Li, Xiaonan1,2,3; Huang, Ruiwang4; Ding, Junhua5; Song, Luping6; Han, Zaizhu1,2 | |
第一作者 | Wang, Ke |
通讯作者邮箱 | zzhhan@bnu.edu.cn(z.han) ; songluping882002@aliyun.com(l.song) |
心理所单位排序 | 2 |
摘要 | Orthographic processing is a critical stage in visual word recognition. However, the white-matter pathways that support this processing are unclear, as prior findings might have been confounded by impure behavioral measures, potential structural reorganization of the brain, and limited sample sizes. To address this issue, we investigated the correlations between the integrity of 20 major tracts in the whole brain and the pure orthographic index across 67 patients with short-term brain damage. The integrity of the tracts was measured by the lesion volume percentage and the mean fractional anisotropy value. The orthographic index was calculated as the residual of the orthographic tasks after regressing out corresponding nonorthographic tasks and the orthographic factor from the principal component analysis (PCA) on the basis of four orthographic tasks. We found significant correlations associated with the left inferior longitudinal fasciculus (ILF), even after controlling for the influence of potential confounding variables. These observations strengthen evidence for the vital role of the left ILF in orthographic processing. |
关键词 | Orthographic processing Connectome Lesion-behavior mapping White-matter tract |
2020-02-01 | |
语种 | 英语 |
DOI | 10.1016/j.bandl.2019.104721 |
发表期刊 | BRAIN AND LANGUAGE |
ISSN | 0093-934X |
卷号 | 201页码:14 |
期刊论文类型 | article |
收录类别 | SCI |
资助项目 | National Key R&D Program of China[2018YFC1315200] ; National Key R&D Program of China[2017YFF0207400] ; National Natural Science Foundation of China[31872785] ; National Natural Science Foundation of China[81171019] ; National Natural Science Foundation of China[81972144] ; National Natural Science Foundation of China[81871338] ; Beijing Natural Science Foundation[7182088] |
出版者 | ACADEMIC PRESS INC ELSEVIER SCIENCE |
WOS关键词 | WORD FORM AREA ; WHITE-MATTER PROPERTIES ; ARCUATE FASCICULUS ; VISUAL-CORTEX ; FUNCTIONAL CONNECTIVITY ; STRUCTURAL CONNECTIVITY ; READING-SKILLS ; NEURAL SYSTEMS ; BRAIN-REGIONS ; LANGUAGE |
WOS研究方向 | Audiology & Speech-Language Pathology ; Linguistics ; Neurosciences & Neurology ; Psychology |
WOS类目 | Audiology & Speech-Language Pathology ; Linguistics ; Neurosciences ; Psychology, Experimental |
WOS记录号 | WOS:000510096500004 |
资助机构 | National Key R&D Program of China ; National Natural Science Foundation of China ; Beijing Natural Science Foundation |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.psych.ac.cn/handle/311026/30828 |
专题 | 中国科学院行为科学重点实验室 |
通讯作者 | Song, Luping; Han, Zaizhu |
作者单位 | 1.Beijing Normal Univ, State Key Lab Cognit Neurosci & Learning, Beijing 100875, Peoples R China 2.Beijing Normal Univ, IDG McGovern Inst Brain Res, Beijing 100875, Peoples R China 3.Chinese Acad Sci, Inst Psychol, CAS Key Lab Behav Sci, Beijing 100101, Peoples R China 4.South China Normal Univ, Sch Psychol, Guangzhou 510631, Peoples R China 5.Baylor Coll Med, Dept Neurosurg, Houston, TX 77030 USA 6.Shenzhen Univ, Dept Rehabil Med, Gen Hosp, Shenzhen 518055, Peoples R China |
推荐引用方式 GB/T 7714 | Wang, Ke,Li, Xiaonan,Huang, Ruiwang,et al. The left inferior longitudinal fasciculus supports orthographic processing: Evidence from a lesion-behavior mapping analysis[J]. BRAIN AND LANGUAGE,2020,201:14. |
APA | Wang, Ke,Li, Xiaonan,Huang, Ruiwang,Ding, Junhua,Song, Luping,&Han, Zaizhu.(2020).The left inferior longitudinal fasciculus supports orthographic processing: Evidence from a lesion-behavior mapping analysis.BRAIN AND LANGUAGE,201,14. |
MLA | Wang, Ke,et al."The left inferior longitudinal fasciculus supports orthographic processing: Evidence from a lesion-behavior mapping analysis".BRAIN AND LANGUAGE 201(2020):14. |
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