Age differences in the fronto-striato-parietal network underlying serial ordering | |
Ye, Zheng1![]() | |
First Author | Ye, Zheng |
Correspondent Email | yez@ion.ac.cn ; thomas.muente@neuro.uni-luebeck.de |
Abstract | Maintaining the ability to arrange thoughts and actions in an appropriate serial order is crucial for complex behavior. We aimed to investigate age differences in the fronto-striato-parietal network underlying serial ordering using functional magnetic resonance imaging. We exposed 25 young and 27 older healthy adults to a digit ordering task, where they had to reorder and recall sequential digits or simply to recall them. We detected a network comprising of the lateral and medial prefrontal, posterior parietal, and striatal regions. In young adults, the prefrontal and parietal regions were more activated and more strongly connected with the supplementary motor area for "reorder & recall" than "pure recall" trials (psychophysiological interaction, PPI). In older adults, the prefrontal and parietal activations were elevated, but the PPI was attenuated. Individual adults who had a stronger PPI performed more accurately in "reorder & recall" trials. The decreased PPI appeared to be compensated by increased physiological correlations between the prefrontal/parietal cortex and the striatum, and by that between the striatum and the supplementary motor area. (C) 2019 The Author(s). Published by Elsevier Inc. |
Keyword | Aging Sequential working memory Serial ordering Prefrontal cortex Parietal cortex Striatum |
2020-03-01 | |
Language | 英语 |
DOI | 10.1016/j.neurobiolaging.2019.12.007 |
Source Publication | NEUROBIOLOGY OF AGING
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ISSN | 0197-4580 |
Volume | 87Pages:115-124 |
Subtype | article |
Indexed By | SCI |
Funding Project | National Natural Science Foundation of China, China[31771216] ; National Natural Science Foundation of China, China[31630034] ; Strategic Priority Research Program of Chinese Academy of Sciences[XDB32020200] ; Shanghai Municipal Science and Technology, China[2018SHZDZX05] ; German Research Foundation, Germany[SFB TR134 C1] ; Alexander von Humboldt Foundation, Germany |
Publisher | ELSEVIER SCIENCE INC |
WOS Keyword | SHORT-TERM-MEMORY ; WORKING-MEMORY ; PREFRONTAL CORTEX ; TEMPORAL-ORDER ; PARKINSONS-DISEASE ; WHITE-MATTER ; OLDER-ADULTS ; BRAIN ; FMRI ; DEFAULT |
WOS Research Area | Geriatrics & Gerontology ; Neurosciences & Neurology |
WOS Subject | Geriatrics & Gerontology ; Neurosciences |
WOS ID | WOS:000518217600014 |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.psych.ac.cn/handle/311026/30988 |
Collection | 健康与遗传心理学研究室 |
Corresponding Author | Ye, Zheng; Muente, Thomas F. |
Affiliation | 1.Chinese Acad Sci, CAS Ctr Excellence Brain Sci & Intelligence Techn, Inst Neurosci, Key Lab Primate Neurobiol, Shanghai, Peoples R China 2.Chinese Acad Sci, Inst Psychol, Beijing, Peoples R China 3.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China 4.Peking Univ, Ctr Brain & Cognit Sci, Sch Psychol & Cognit Sci, Beijing, Peoples R China 5.Peking Univ, Dept Neurol, Hosp 3, Beijing, Peoples R China 6.Peking Univ, PKU IDG McGovern Inst Brain Res, Beijing, Peoples R China 7.Univ Lubeck, Dept Neurol, Ratzeburger Allee 160, D-23538 Lubeck, Germany |
Recommended Citation GB/T 7714 | Ye, Zheng,Zhang, Guanyu,Li, Shuaiqi,et al. Age differences in the fronto-striato-parietal network underlying serial ordering[J]. NEUROBIOLOGY OF AGING,2020,87:115-124. |
APA | Ye, Zheng.,Zhang, Guanyu.,Li, Shuaiqi.,Zhang, Yingshuang.,Xiao, Weizhong.,...&Muente, Thomas F..(2020).Age differences in the fronto-striato-parietal network underlying serial ordering.NEUROBIOLOGY OF AGING,87,115-124. |
MLA | Ye, Zheng,et al."Age differences in the fronto-striato-parietal network underlying serial ordering".NEUROBIOLOGY OF AGING 87(2020):115-124. |
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