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Men and women differ in the neural basis of handwriting | |
Yang, Yang1,2,3; Tam, Fred4; Graham, Simon J.4,5; Sun, Guochen6; Li, Junjun1,2; Gu, Chanyuan1,2; Tao, Ran7; Wang, Nizhuan8; Bi, Hong-Yan1,2; Zuo, Zhentao9,10,11 | |
第一作者 | Yang, Yang |
通讯作者邮箱 | yangyang@psych.ac.cn ; ztzuo@bcslab.ibp.ac.cn |
心理所单位排序 | 1 |
摘要 | There is an ongoing debate about whether, and to what extent, males differ from females in their language skills. In the case of handwriting, a composite language skill involving language and motor processes, behavioral observations consistently show robust sex differences but the mechanisms underlying the effect are unclear. Using functional magnetic resonance imaging (fMRI) in a copying task, the present study examined the neural basis of sex differences in handwriting in 53 healthy adults (ages 19-28, 27 males). Compared to females, males showed increased activation in the left posterior middle frontal gyrus (Exner's area), a region thought to support the conversion between orthographic and graphomotor codes. Functional connectivity between Exner's area and the right cerebellum was greater in males than in females. Furthermore, sex differences in brain activity related to handwriting were independent of language material. This study identifies a novel neural signature of sex differences in a hallmark of human behavior, and highlights the importance of considering sex as a factor in scientific research and clinical applications involving handwriting. |
关键词 | Exner's area fMRI handwriting sex differences |
2020-02-24 | |
语种 | 英语 |
DOI | 10.1002/hbm.24968 |
发表期刊 | HUMAN BRAIN MAPPING |
ISSN | 1065-9471 |
页码 | 14 |
收录类别 | SCI ; SSCI |
出版者 | WILEY |
WOS关键词 | WRITTEN WORD PRODUCTION ; SEX-DIFFERENCES ; GENDER-DIFFERENCES ; ACADEMIC-ACHIEVEMENT ; BRAIN ACTIVATION ; FUNCTIONAL MRI ; LANGUAGE ; FMRI ; MOTOR ; METAANALYSIS |
WOS研究方向 | Neurosciences & Neurology ; Radiology, Nuclear Medicine & Medical Imaging |
WOS类目 | Neurosciences ; Neuroimaging ; Radiology, Nuclear Medicine & Medical Imaging |
WOS记录号 | WOS:000515143500001 |
Q分类 | Q1 |
资助机构 | National Natural Science Foundation of China ; Shenzhen Peacock Plan ; Guangdong Pearl River Talents Plan Innovative and Entrepreneurial Team grant ; CAS Key Laboratory of Behavioral Science, Institute of Psychology ; Shenzhen Fundamental Research Project ; Project of Six Talent Peaks of Jiangsu Province |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.psych.ac.cn/handle/311026/30994 |
专题 | 中国科学院行为科学重点实验室 |
通讯作者 | Yang, Yang; Zuo, Zhentao |
作者单位 | 1.Chinese Acad Sci, Inst Psychol, Ctr Brain Sci & Learning Difficulties, Key Lab Behav Sci, Beijing, Peoples R China 2.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China 3.Shenzhen Inst Neurosci, Ctr Language, Shenzhen, Peoples R China 4.Sunnybrook Res Inst, Phys Sci Platform, Toronto, ON, Canada 5.Univ Toronto, Dept Med Biophys, Toronto, ON, Canada 6.Chinese Peoples Liberat Army Gen Hosp, Dept Neurosurg, Med Ctr 1, Tianjin, Peoples R China 7.Hong Kong Polytech Univ, Dept Chinese & Bilingual Studies, Kowloon, Hong Kong, Peoples R China 8.Jiangsu Ocean Univ, Sch Comp Engn, Artificial Intelligence & Neuroinformat Engn ARIN, Lianyungang, Peoples R China 9.Chinese Acad Sci, Inst Biophys, State Key Lab Brain & Cognit Sci, Beijing, Peoples R China 10.Chinese Acad Sci, Innovat Ctr Excellence Brain Sci, Beijing, Peoples R China 11.Univ Chinese Acad Sci, Sino Danish Coll, Beijing, Peoples R China |
通讯作者单位 | 脑与认知科学国家重点实验室 |
推荐引用方式 GB/T 7714 | Yang, Yang,Tam, Fred,Graham, Simon J.,et al. Men and women differ in the neural basis of handwriting[J]. HUMAN BRAIN MAPPING,2020:14. |
APA | Yang, Yang.,Tam, Fred.,Graham, Simon J..,Sun, Guochen.,Li, Junjun.,...&Zuo, Zhentao.(2020).Men and women differ in the neural basis of handwriting.HUMAN BRAIN MAPPING,14. |
MLA | Yang, Yang,et al."Men and women differ in the neural basis of handwriting".HUMAN BRAIN MAPPING (2020):14. |
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