PSYCH OpenIR  > 中国科学院行为科学重点实验室
CHIMGEN: a Chinese imaging genetics cohort to enhance cross-ethnic and cross-geographic brain research
Xu, Qiang1,2; Guo, Lining1,2; Cheng, Jingliang3; Wang, Meiyun4,5,6; Geng, Zuojun7; Zhu, Wenzhen8; Zhang, Bing9; Liao, Weihua10,11; Qiu, Shijun12; Zhang, Hui13; Xu, Xiaojun14; Yu, Yongqiang15; Gao, Bo16; Han, Tong17,18; Yao, Zhenwei19; Cui, Guangbin20,21; Liu, Feng1,2; Qin, Wen1,2; Zhang, Quan1,2; Li, Mulin Jun22; Liang, Meng23; Chen, Feng24; Xian, Junfang25; Li, Jiance26; Zhang, Jing27; Zuo, Xi-Nian28,29; Wang, Dawei30; Shen, Wen31; Miao, Yanwei32; Yuan, Fei33; Lui, Su34,35,36; Zhang, Xiaochu37,38; Xu, Kai39,40; Zhang, Long Jiang41; Ye, Zhaoxiang42; Yu, Chunshui1,2,43
First AuthorXu, Qiang
Correspondent Emailchunshui yu chunshuiyu@tmu.edu.cn
2020-03-01
Source PublicationMOLECULAR PSYCHIATRY
ISSN1359-4184
Subtypearticle
Volume25Issue:3Pages:517-529
QuartileQ1
Abstract

The Chinese Imaging Genetics (CHIMGEN) study establishes the largest Chinese neuroimaging genetics cohort and aims to identify genetic and environmental factors and their interactions that are associated with neuroimaging and behavioral phenotypes. This study prospectively collected genomic, neuroimaging, environmental, and behavioral data from more than 7000 healthy Chinese Han participants aged 18-30 years. As a pioneer of large-sample neuroimaging genetics cohorts of non-Caucasian populations, this cohort can provide new insights into ethnic differences in genetic-neuroimaging associations by being compared with Caucasian cohorts. In addition to micro-environmental measurements, this study also collects hundreds of quantitative macro-environmental measurements from remote sensing and national survey databases based on the locations of each participant from birth to present, which will facilitate discoveries of new environmental factors associated with neuroimaging phenotypes. With lifespan environmental measurements, this study can also provide insights on the macro-environmental exposures that affect the human brain as well as their timing and mechanisms of action.

DOI10.1038/s41380-019-0627-6
Indexed BySCI
Language英语
WOS Research AreaBiochemistry & Molecular Biology ; Neurosciences & Neurology ; Psychiatry
WOS SubjectBiochemistry & Molecular Biology ; Neurosciences ; Psychiatry
WOS IDWOS:000516569700006
PublisherNATURE PUBLISHING GROUP
WOS KeywordGENOME-WIDE ASSOCIATION ; ENVIRONMENT INTERACTION ; RISK PREDICTION ; WORKING-MEMORY ; PERSPECTIVE ; PHENOTYPES ; CHILDHOOD ; IMPACTS ; SCHIZOPHRENIA ; HERITABILITY
Citation statistics
Cited Times:3[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.psych.ac.cn/handle/311026/31398
Collection中国科学院行为科学重点实验室
Corresponding AuthorYu, Chunshui
Affiliation1.Tianjin Med Univ Gen Hosp, Dept Radiol, Tianjin 300052, Peoples R China
2.Tianjin Med Univ Gen Hosp, Tianjin Key Lab Funct Imaging, Tianjin 300052, Peoples R China
3.Zhengzhou Univ, Affiliated Hosp 1, Dept Magnet Resonance Imaging, Zhengzhou 450052, Peoples R China
4.Zhengzhou Univ Peoples Hosp, Dept Radiol, Zhengzhou 450003, Peoples R China
5.Henan Prov Peoples Hosp, Zhengzhou 450003, Peoples R China
6.Henan Key Lab Med Imaging Neurol Dis, Zhengzhou 450003, Peoples R China
7.Hebei Med Univ, Hosp 2, Dept Med Imaging, Shijiazhuang 050000, Hebei, Peoples R China
8.Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Dept Radiol, Wuhan 430030, Peoples R China
9.Nanjing Univ, Dept Radiol, Med Sch, Drum Tower Hosp, Nanjing 210008, Peoples R China
10.Cent South Univ, Xiangya Hosp, Dept Radiol, Changsha 410008, Peoples R China
11.Natl Clin Res Ctr Geriatr Disorder, Changsha 410008, Peoples R China
12.Guangzhou Univ Chinese Med, Dept Med Imaging, Affiliated Hosp 1, Guangzhou 510405, Peoples R China
13.Shanxi Med Univ, Hosp 1, Dept Radiol, Taiyuan 030001, Peoples R China
14.Zhejiang Univ, Sch Med, Dept Radiol, Affiliated Hosp 2, Hangzhou 310009, Peoples R China
15.Anhui Med Univ, Dept Radiol, Affiliated Hosp 1, Hefei 230022, Peoples R China
16.Yantai Yuhuangding Hosp, Dept Radiol, Yantai 264000, Peoples R China
17.Tianjin Huanhu Hosp, Dept Radiol, Tianjin 300350, Peoples R China
18.Tianjin Key Lab Cerebral Vasc & Neurodegenerat Di, Tianjin 300350, Peoples R China
19.Fudan Univ, Dept Radiol, Huashan Hosp, Shanghai 200040, Peoples R China
20.Mil Med Univ PLA Airforce, Mil Med Univ 4, Funct & Mol Imaging Key Lab Shaanxi Prov, Tangdu Hosp, Xian 710038, Peoples R China
21.Mil Med Univ PLA Airforce, Mil Med Univ 4, Dept Radiol, Tangdu Hosp, Xian 710038, Peoples R China
22.Tianjin Med Univ, Collaborat Innovat Ctr Tianjin Med Epigenet, Sch Basic Med Sci, Tianjin Key Lab Med Epigenet, Tianjin 300070, Peoples R China
23.Tianjin Med Univ, Sch Med Imaging, Tianjin 300203, Peoples R China
24.Hainan Gen Hosp, Dept Radiol, Haikou 570311, Hainan, Peoples R China
25.Capital Med Univ, Beijing Tongren Hosp, Dept Radiol, Beijing 100730, Peoples R China
26.Wenzhou Med Univ, Dept Radiol, Affiliated Hosp 1, Wenzhou 325000, Peoples R China
27.Lanzhou Univ, Dept Magnet Resonance, Hosp 2, Lanzhou 730050, Peoples R China
28.Univ Chinese Acad Sci CAS, Dept Psychol, Beijing 100049, Peoples R China
29.Inst Psychol, CAS Key Lab Behav Sci, Beijing 100101, Peoples R China
30.Shandong Univ, Dept Radiol, Qilu Hosp, Jinan 250012, Peoples R China
31.Tianjin First Ctr Hosp, Dept Radiol, Tianjin 300192, Peoples R China
32.Dalian Med Univ, Dept Radiol, Affiliated Hosp 1, Dalian 116011, Peoples R China
33.Logist Univ Chinese Peoples Armed Police Forces, Pingjin Hosp, Dept Radiol, Tianjin 300162, Peoples R China
34.Sichuan Univ, Ctr Med Imaging, Dept Radiol, West China Hosp, Chengdu 610041, Peoples R China
35.Wenzhou Med Univ, Dept Radiol, Affiliated Hosp 2, Wenzhou 325000, Peoples R China
36.Wenzhou Med Univ, Yuying Childrens Hosp, Wenzhou 325000, Peoples R China
37.Univ Sci & Technol China, CAS Key Lab Brain Funct & Dis, Hefei 230026, Peoples R China
38.Univ Sci & Technol China, Sch Life Sci, Hefei 230026, Peoples R China
39.Xuzhou Med Univ, Affiliated Hosp, Dept Radiol, Xuzhou 221006, Jiangsu, Peoples R China
40.Xuzhou Med Univ, Sch Med Imaging, Xuzhou 221004, Jiangsu, Peoples R China
41.Nanjing Univ, Dept Med Imaging, Jinling Hosp, Med Sch, Nanjing 210002, Peoples R China
42.Tianjin Med Univ Canc Inst & Hosp, Dept Radiol, Natl Clin Res Ctr Canc, Tianjins Clin Res Ctr Canc,Key Lab Canc Prevent &, Tianjin 300060, Peoples R China
43.Chinese Acad Sci, CAS Ctr Excellence Brain Sci & Intelligence Techn, Shanghai 200031, Peoples R China
Recommended Citation
GB/T 7714
Xu, Qiang,Guo, Lining,Cheng, Jingliang,et al. CHIMGEN: a Chinese imaging genetics cohort to enhance cross-ethnic and cross-geographic brain research[J]. MOLECULAR PSYCHIATRY,2020,25(3):517-529.
APA Xu, Qiang.,Guo, Lining.,Cheng, Jingliang.,Wang, Meiyun.,Geng, Zuojun.,...&Yu, Chunshui.(2020).CHIMGEN: a Chinese imaging genetics cohort to enhance cross-ethnic and cross-geographic brain research.MOLECULAR PSYCHIATRY,25(3),517-529.
MLA Xu, Qiang,et al."CHIMGEN: a Chinese imaging genetics cohort to enhance cross-ethnic and cross-geographic brain research".MOLECULAR PSYCHIATRY 25.3(2020):517-529.
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