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Sex differences in psychotic and non-psychotic major depressive disorder in a Chinese Han population
Qi, Ling1; Zhang, Yaping2,3; Wang, Liewei4; Wang, Ruoxi5; Wu, Jiang6; Zhou, Xin2; Chen, Jing2,3; Zhang, Shufang2,3; Zhou, Yongjie2,3; Zhang, Xiang Yang7,8
First AuthorQi, Ling
Correspondent Emailqingzhu1108@126.com (y. zhou) ; zhangxy@psych.ac.cn (x.y. zhang)
2020-05-01
Source PublicationJOURNAL OF AFFECTIVE DISORDERS
ISSN0165-0327
Subtypearticle
Volume268Pages:55-60
QuartileQ1
Contribution Rank7
Abstract

Background: Sex differences between psychotic depression (PD) and non-psychotic depression (NPD) have received little systematic study. This study was conducted to investigate sex difference in patients with psychotic and non-psychotic major depressive disorder in a Chinese Han population. Methods: In this cross-sectional study, a total of 1718 first-episode and drug-naive outpatients with major depressive disorder were recruited. Demographic and clinical characteristics were collected. All subjects were rated on the Hamilton Depression Rating Scale (HAMD), Hamilton Anxiety Rating Scale (HAMA) and the Positive and Negative Syndrome Scale (PANSS). Results: The prevalence of PD in female patients (10.97%) was higher than that in male patients (7.99%). Analysis of variance (ANOVA) showed that female patients were older compared with male patients in NPD group, but there were no significant differences in demographic and clinical variables between female and male PD patients. Further, there were no sex differences in the scores of HAMD, HAMA and positive symptom subscale of PANSS in both PD and NPD groups. Two-way ANOVA showed that PD patients had significantly higher scores on the HAMD, HAMA and positive symptom subscale of PANSS than non-PD patients. However, there were no significant effects of sex and sex* subtypes. Limitations: The main limitations are cross-sectional design and inability to control selection bias. Conclusions: Our findings show significant differences in clinical profiles between PD and NPD patients; however, no sex difference has been observed in the either PD or NPD patients.

DOI10.1016/j.jad.2020.03.003
Indexed BySCI
Language英语
Funding OrganizationResearch Project of Wuhan Health and Planning Business Committee
Funding ProjectResearch Project of Wuhan Health and Planning Business Committee[WX15C06]
WOS Research AreaNeurosciences & Neurology ; Psychiatry
WOS SubjectClinical Neurology ; Psychiatry
WOS IDWOS:000520891900007
PublisherELSEVIER
WOS KeywordNATIONAL EPIDEMIOLOGIC SURVEY ; GENDER-DIFFERENCES ; MENTAL-DISORDERS ; CLINICAL CHARACTERISTICS ; PREVALENCE ; FEATURES ; NETHERLANDS ; SUICIDE ; RISK ; AGE
Citation statistics
Cited Times:2[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.psych.ac.cn/handle/311026/31479
Collection中国科学院心理健康重点实验室
Corresponding AuthorZhou, Yongjie; Zhang, Xiang Yang
Affiliation1.Wuhan Polytech Univ, Sch Hlth Sci & Nursing, Wuhan, Peoples R China
2.China Univ Geosci, Res Ctr Psychol & Hlth Sci, Wuhan, Peoples R China
3.Huazhong Univ Sci & Technol, Affiliated Wuhan Mental Hlth Ctr, Tongji Med Coll, Wuhan, Peoples R China
4.Wuhan Xinzhou Dist Mental Hlth Ctr, Wuhan, Peoples R China
5.Huazhong Univ Sci & Technol, Sch Med & Hlth Management, Tongji Med Coll, Wuhan, Peoples R China
6.Wuhan Youfu Hosp, Med Dept, Wuhan, Peoples R China
7.Chinese Acad Sci, Inst Psychol, CAS Key Lab Mental Hlth, Beijing, Peoples R China
8.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China
Corresponding Author AffilicationKey Laboratory of Mental Health, CAS
Recommended Citation
GB/T 7714
Qi, Ling,Zhang, Yaping,Wang, Liewei,et al. Sex differences in psychotic and non-psychotic major depressive disorder in a Chinese Han population[J]. JOURNAL OF AFFECTIVE DISORDERS,2020,268:55-60.
APA Qi, Ling.,Zhang, Yaping.,Wang, Liewei.,Wang, Ruoxi.,Wu, Jiang.,...&Zhang, Xiang Yang.(2020).Sex differences in psychotic and non-psychotic major depressive disorder in a Chinese Han population.JOURNAL OF AFFECTIVE DISORDERS,268,55-60.
MLA Qi, Ling,et al."Sex differences in psychotic and non-psychotic major depressive disorder in a Chinese Han population".JOURNAL OF AFFECTIVE DISORDERS 268(2020):55-60.
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