PSYCH OpenIR  > 中国科学院心理健康重点实验室
Prevalence and related factors of suicide attempts in first-episode and untreated Chinese Han outpatients with psychotic major depression
Li, Hehua1; Huang, Yuanyuan1; Wu, Fengchun1,2; Lang, XiaoE3; Zhang, Xiang Yang1,4,5
First AuthorLi, Hehua
Correspondent Email13580380071@163.com (f. wu) ; zhangxy@psych.ac.cn (x.y. zhang)
Contribution Rank3
Abstract

Background: Major depressive depression (MDD) is often accompanied by suicidal behavior. Increasing evidence shows that MDD patients display psychotic symptoms. However, the relationship between psychotic symptoms and suicide attempt in MDD has not been reported. Therefore, this study was to identify the prevalence and associated factors of suicide attempts in first-episode and untreated Chinese Han outpatients comorbid with psychotic major depression (PMD). Methods: 1718 first-episode and untreated MDD outpatients were assessed with Positive Symptom Scale of Positive and Negative Syndrome Scale (PANSS), the 17-item Hamilton Depression Scale, Hamilton Anxiety Scale, and clinical global impression of severity scale (CGI-S). Some glycolipid metabolism and thyroid hormone parameters were measured. Results: In MDD patients, the percentage of PMD was 10.0%. The incidence of attempted suicide in PMD patients was 51.5%, which was more than 3 times higher than that in non-PMD patients (16.7%). In PMD patients, compared to non-attempters, suicide attempters were older, had a longer course of disease, scored higher on all scales, as well as had higher levels of thyroid stimulating hormone (TSH), thyroid peroxidases antibody, antithyroglobulin and blood glucose. PANSS positive symptom, CGI, diastolic blood pressure and TSH were independently associated with suicide attempts of PMD. Conclusions: PMD patients have a higher prevalence of suicide attempt than non-PMD patients. Some demographic and clinical parameters are relevant factors for suicide attempt in PMD patients.

KeywordMajor depressive disorder Psychotic symptom Suicide attempts Prevalence Correlates
2020-06-01
Language英语
DOI10.1016/j.jad.2020.03.093
Source PublicationJOURNAL OF AFFECTIVE DISORDERS
ISSN0165-0327
Volume270Pages:108-113
SubtypeArticle
Indexed BySCI
Funding ProjectNational Natural Science Foundation of China[31771074] ; Scientific research project of traditional Chinese medicine of Guangdong[20192070] ; Science and technology project of Liwan district[201804011] ; Science and Technology Program of Guangzhou[201807010064] ; Science and Technology Program of Guangzhou[201704020168] ; Science and Technology Program of Guangzhou[201804010259]
PublisherELSEVIER
WOS KeywordRISK-FACTORS ; OLDER-PEOPLE ; FEATURES ; DISORDERS ; DELUSIONS ; DIAGNOSIS ; VALIDITY ; IDEATION ; AGE
WOS Research AreaNeurosciences & Neurology ; Psychiatry
WOS SubjectClinical Neurology ; Psychiatry
WOS IDWOS:000529319400018
QuartileQ1
Citation statistics
Cited Times:4[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.psych.ac.cn/handle/311026/31730
Collection中国科学院心理健康重点实验室
Corresponding AuthorWu, Fengchun; Zhang, Xiang Yang
Affiliation1.Guangzhou Med Univ, Dept Psychiat, Affiliated Brain Hosp, Guangzhou Huiai Hosp, Guangzhou, Peoples R China
2.Guangdong Engn Technol Res Ctr Translat Med Menta, Guangzhou, Peoples R China
3.Shanxi Med Univ, Clin Med Coll 1, Dept Psychiat, Taiyuan, Shanxi, Peoples R China
4.Chinese Acad Sci, Inst Psychol, CAS Key Lab Mental Hlth, Beijing, Peoples R China
5.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China
Corresponding Author AffilicationKey Laboratory of Mental Health, CAS
Recommended Citation
GB/T 7714
Li, Hehua,Huang, Yuanyuan,Wu, Fengchun,et al. Prevalence and related factors of suicide attempts in first-episode and untreated Chinese Han outpatients with psychotic major depression[J]. JOURNAL OF AFFECTIVE DISORDERS,2020,270:108-113.
APA Li, Hehua,Huang, Yuanyuan,Wu, Fengchun,Lang, XiaoE,&Zhang, Xiang Yang.(2020).Prevalence and related factors of suicide attempts in first-episode and untreated Chinese Han outpatients with psychotic major depression.JOURNAL OF AFFECTIVE DISORDERS,270,108-113.
MLA Li, Hehua,et al."Prevalence and related factors of suicide attempts in first-episode and untreated Chinese Han outpatients with psychotic major depression".JOURNAL OF AFFECTIVE DISORDERS 270(2020):108-113.
Files in This Item:
File Name/Size DocType Version Access License
Prevalence and relat(243KB)期刊论文出版稿限制开放CC BY-NC-SAApplication Full Text
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Li, Hehua]'s Articles
[Huang, Yuanyuan]'s Articles
[Wu, Fengchun]'s Articles
Baidu academic
Similar articles in Baidu academic
[Li, Hehua]'s Articles
[Huang, Yuanyuan]'s Articles
[Wu, Fengchun]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Li, Hehua]'s Articles
[Huang, Yuanyuan]'s Articles
[Wu, Fengchun]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.