The nature and extent of working memory dysfunction in schizophrenia

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	The nature and extent of working memory dysfunction in schizophrenia
	Xiao-yan Cao1,2 ; Zhi Li 1; Hugo M. Metcalfe 1; Tian-xiao Yang1 ; Shu-ping Tan 3; Ya Wang1 ; Xiao-hong Hong 4; Zhan-jiang Li 5; Xin Yu 6; Eric F. C. Cheung 7; David L. Neumann 8,9; David H. K. Shum 8; Raymond C. K. Chan1 1
第一作者	Xiao-yan Cao
通讯作者邮箱	rckchan@psych.ac.cn
心理所单位排序	1
摘要	This study aimed to examine verbal and visual-spatial working memory (WM) dysfunction in patients with schizophrenia. We compared 60 patients with schizophrenia with 57 healthy controls (matched for age, educational level, and IQ) on three WM tasks. Patients with schizophrenia performed significantly more poorly than healthy controls on verbal, visual, and spatial WM tests. Moreover, WM deficits were inversely associated with both the positive and negative symptoms of the patients. Taken together, these findings suggest that there are pervasive WM impairments in patients with schizophrenia. In addition, clinical features may play a significant role in the expression of WM deficits.
关键词	schizophrenia spatial verbal working memory
	2013
语种	英语
发表期刊	PsyCh Journal
ISSN	2046-0260
卷号	2 页码:175-182
期刊论文类型	article
收录类别	SSCI ; SSCI
文献类型	期刊论文
条目标识符	https://ir.psych.ac.cn/handle/311026/31881
专题	中国科学院心理研究所
作者单位	1.Neuropsychology and Applied Cognitive Neuroscience Laboratory, Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China 2.University of Chinese Academy of Sciences, Beijing, China 3.Beijing Huilongguan Hospital, Beijing, China 4.Mental Health Center, Shantou University, Shantou, China 5.Beijing Anding Hospital, Capital Medical University, Beijing, China 6.Institute of Mental Health, the Sixth Affiliated Hospital, Peking University, Beijing, China 7.Castle Peak Hospital, Hong Kong Special Administrative Region, China 8.Behavioural Basis of Health Research Program, Griffith Health Institute, Griffith University, Gold Coast Australia 9.School of Applied Psychology, Griffith University, Gold Coast Australia
第一作者单位	中国科学院心理研究所
推荐引用方式 GB/T 7714	Xiao-yan Cao,Zhi Li,Hugo M. Metcalfe,et al. The nature and extent of working memory dysfunction in schizophrenia[J]. PsyCh Journal,2013,2:175-182.
APA	Xiao-yan Cao.,Zhi Li.,Hugo M. Metcalfe.,Tian-xiao Yang.,Shu-ping Tan.,...&Raymond C. K. Chan1.(2013).The nature and extent of working memory dysfunction in schizophrenia.PsyCh Journal,2,175-182.
MLA	Xiao-yan Cao,et al."The nature and extent of working memory dysfunction in schizophrenia".PsyCh Journal 2(2013):175-182.

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