Revisiting anticipatory hedonic processing in patients with schizophrenia: An examination between representation activation and maintenance

doi:10.1016/j.schres.2019.12.013

	Revisiting anticipatory hedonic processing in patients with schizophrenia: An examination between representation activation and maintenance
	Wang, Ling-ling 1,2,3; Yan, Chao1 ; Shao, Yu-xin 1; Lv, Qin-yu 4; Neumann, David 5; Ettinger, Ulrich 6; Cheung, Eric F. C.7; Yi, Zheng-hui 4; Chan, Raymond C. K.2,3
通讯作者	Yan, Chao(cyan@psy.ecnu.edu.cn) ; Yi, Zheng-hui(yizhenghui1971@163.com) ; Chan, Raymond C. K.(rckchan@psych.ac.cn)
摘要	Background: Anticipatory anhedonia is one of the key deficits found in patients with schizophrenia (SCZ). However, the underlying mechanism of this deficit remains unclear. The present study examined whether representation activation and maintenance capacity influenced anticipatory experiences in SCZ patients. Methods: We recruited 46 SCZ patients (26 males) and 45 matched healthy controls (24 males).The Reward Representation Activation and Maintenance (RRAM) Task was administrated to assess anticipatory experience and representation activation and maintenance capacity. Results: SCZ patients exhibited lower subjective arousal than controls in anticipation of rewards with high probability when representation activation and maintenance were difficult to accomplish. SCZ patients also tended to reduce their button presses more than HC when they were required to maintain reward representation. Conclusions: Our findings suggest that representation activation and maintenance may partially account for anticipatory anhedonia observed in SCZ patients. (C) 2019 Elsevier B.V. All rights reserved.
关键词	Representation activation Representation maintenance Anticipatory anhedonia Schizophrenia
	2020-02-01
语种	英语
DOI	10.1016/j.schres.2019.12.013
发表期刊	SCHIZOPHRENIA RESEARCH
ISSN	0920-9964
卷号	216 页码:138-146
收录类别	SCI
资助项目	National Natural Science Foundation China[31500894] ; National Natural Science Foundation China[81671326] ; National Natural Science Foundation China[81571317] ; National Key Research and Development Program of China[2016YFC0906402] ; Beijing Municipal Science and Technology Commission[Z161100000216138] ; Key Specialist Projects of Shanghai Municipal Commission of Health and Family Planning Foundation[ZK2015B01] ; Programs Foundation of Shanghai Municipal Commission of Health and Family Planning Foundation[201540114] ; Fundamental Research Funds for the Central Universities[2018ECNUQKT015] ; Fundamental Research Funds for the Central Universities[2019ECNU-HWFW021]
出版者	ELSEVIER
WOS关键词	NEGATIVE SYMPTOMS ; MEMORY ERRORS ; MOTIVATION ; PLEASURE
WOS研究方向	Psychiatry
WOS类目	Psychiatry
WOS记录号	WOS:000535701000019
资助机构	National Natural Science Foundation China ; National Key Research and Development Program of China ; Beijing Municipal Science and Technology Commission ; Key Specialist Projects of Shanghai Municipal Commission of Health and Family Planning Foundation ; Programs Foundation of Shanghai Municipal Commission of Health and Family Planning Foundation ; Fundamental Research Funds for the Central Universities
引用统计	被引频次：2[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	https://ir.psych.ac.cn/handle/311026/31979
专题	中国科学院心理健康重点实验室
通讯作者	Yan, Chao; Yi, Zheng-hui; Chan, Raymond C. K.
作者单位	1.East China Normal Univ, Shanghai Changning ECNU Mental Hlth Ctr, Sch Psychol & Cognit Sci, Key Lab Brain Funct Genom MOE & STCSM, Shanghai, Peoples R China 2.Chinese Acad Sci, Inst Psychol, CAS Key Lab Mental Hlth, Neuropsychol & Appl Cognit Neurosci Lab, Beijing, Peoples R China 3.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China 4.Shanghai Jiao Tong Univ, Shanghai Mental Hlth Ctr, Schizophrenia Program, Sch Med, Shanghai, Peoples R China 5.Griffith Univ, Sch Appl Psychol, Hlth Grp, Brisbane, Qld, Australia 6.Univ Bonn, Dept Psychol, Bonn, Germany 7.Castle Peak Hosp, Hong Kong, Peoples R China
第一作者单位	认知与发展心理学研究室
通讯作者单位	认知与发展心理学研究室
推荐引用方式 GB/T 7714	Wang, Ling-ling,Yan, Chao,Shao, Yu-xin,et al. Revisiting anticipatory hedonic processing in patients with schizophrenia: An examination between representation activation and maintenance[J]. SCHIZOPHRENIA RESEARCH,2020,216:138-146.
APA	Wang, Ling-ling.,Yan, Chao.,Shao, Yu-xin.,Lv, Qin-yu.,Neumann, David.,...&Chan, Raymond C. K..(2020).Revisiting anticipatory hedonic processing in patients with schizophrenia: An examination between representation activation and maintenance.SCHIZOPHRENIA RESEARCH,216,138-146.
MLA	Wang, Ling-ling,et al."Revisiting anticipatory hedonic processing in patients with schizophrenia: An examination between representation activation and maintenance".SCHIZOPHRENIA RESEARCH 216(2020):138-146.