Food cue recruits increased reward processing and decreased inhibitory control processing in the obese/overweight: An activation C likelihood estimation meta-analysis of fMRI studies

doi:10.1016/j.orcp.2020.02.004

	Food cue recruits increased reward processing and decreased inhibitory control processing in the obese/overweight: An activation C likelihood estimation meta-analysis of fMRI studies
	Meng, Xia 1,2; Huang, Duo 1,2; Ao, Hua 1,2; Wang, Xinyu 1,2; Gao, Xiao 1,2,3
通讯作者	Gao, Xiao(gaoxiaox@swu.edu.cn)
摘要	Introduction: Growing researches have shown that obese/overweight and healthy weight individuals exhibit different neural responses to food-related stimuli. Accordingly, researchers proposed several theories to explain these differences. Hereon, meta-analyses were conducted using activation likelihood estimation (ALE) to verify these theories and specify the reason of overeating from two aspects. Materials and Methods: Pubmed, Web of Science and Neurosynth were searched for the current study and screened according to inclusion criteria. Firstly, neural responses to visual food cues versus non-food images were compared between obese/overweight and healthy weight individuals. Then, neural activation to high-calorie food images versus low-calorie food/non-food visual stimuli was further investigated among the two populations. Coordinates in included studies were recorded and analysed by Ginger ALE software under threshold at uncorrected p < 0.001 with cluster-level p < 0.05 (cFWE). Results: Eleven and seven studies were found in the first and second set of meta-analysis, respectively. The first meta-analysis showed that obese/overweight have hyper-responsivity in reward area and hyporesponsivity in both gustatory processing and inhibitory control area. The second meta-analysis indicated that the reward responsivity in the obese/overweight individuals was amplified and healthy weight individuals had higher activation in areas associated with gustatory processing in response to high-calorie food images. Conclusions: Our results showed that the obese/overweight exhibit hyper-responsivity in brain regions involved in reward processing for visual food cue which provide strong support for incentive-sensitization theory of obesity and healthy weight individuals showed higher response in inhibitory control region which support the inhibitory control deficit theory of obesity. (C) 2020 Asia Oceania Association for the Study of Obesity. Published by Elsevier Ltd. All rights reserved.
关键词	obese/overweight Visual food cues Neural activation Reward processing Inhibitory control
	2020-03-01
语种	英语
DOI	10.1016/j.orcp.2020.02.004
发表期刊	OBESITY RESEARCH & CLINICAL PRACTICE
ISSN	1871-403X
卷号	14 期号:2 页码:127-135
收录类别	SCI
资助项目	Chongqing Social Science Planning Project[2019PY57] ; Central Universities Fundamental Research Funds[SWU1809103] ; CAS Key Laboratory of Mental Health, Institute of Psychology[KLMH2016G04]
出版者	ELSEVIER SCI LTD
WOS关键词	DORSOLATERAL PREFRONTAL CORTEX ; DIRECT-CURRENT STIMULATION ; FUNCTIONAL CONNECTIVITY ; BRAIN ACTIVATION ; NEURAL RESPONSES ; LESS ACTIVATION ; NORMAL-WEIGHT ; HIGH-CALORIE ; OBESE ; WOMEN
WOS研究方向	Endocrinology & Metabolism ; Nutrition & Dietetics
WOS类目	Endocrinology & Metabolism ; Nutrition & Dietetics
WOS记录号	WOS:000535748900004
资助机构	Chongqing Social Science Planning Project ; Central Universities Fundamental Research Funds ; CAS Key Laboratory of Mental Health, Institute of Psychology
引用统计	被引频次：25[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.psych.ac.cn/handle/311026/31997
专题	中国科学院心理健康重点实验室
通讯作者	Gao, Xiao
作者单位	1.Southwest Univ, Key Lab Cognit & Personal, Minist Educ, Chongqing 400715, Peoples R China 2.Southwest Univ, Fac Psychol, Chongqing 400715, Peoples R China 3.Inst Psychol, CAS Key Lab Mental Hlth, Beijing 100101, Peoples R China
通讯作者单位	中国科学院心理健康重点实验室
推荐引用方式 GB/T 7714	Meng, Xia,Huang, Duo,Ao, Hua,et al. Food cue recruits increased reward processing and decreased inhibitory control processing in the obese/overweight: An activation C likelihood estimation meta-analysis of fMRI studies[J]. OBESITY RESEARCH & CLINICAL PRACTICE,2020,14(2):127-135.
APA	Meng, Xia,Huang, Duo,Ao, Hua,Wang, Xinyu,&Gao, Xiao.(2020).Food cue recruits increased reward processing and decreased inhibitory control processing in the obese/overweight: An activation C likelihood estimation meta-analysis of fMRI studies.OBESITY RESEARCH & CLINICAL PRACTICE,14(2),127-135.
MLA	Meng, Xia,et al."Food cue recruits increased reward processing and decreased inhibitory control processing in the obese/overweight: An activation C likelihood estimation meta-analysis of fMRI studies".OBESITY RESEARCH & CLINICAL PRACTICE 14.2(2020):127-135.