Institutional Repository of Key Laboratory of Behavioral Science, CAS
Effects of Caffeine on Event-Related Potentials and Neuropsychological Indices After Sleep Deprivation | |
Chen, Xuewei1; Zhang, Liwei2; Yang, Danfeng1; Li, Chao1; An, Gaihong1; Wang, Jing1![]() | |
第一作者 | Chen, Xuewei |
通讯作者邮箱 | rong fan prosperity_39@sina.cn ; qiang ma maqiangw@sohu.com |
心理所单位排序 | 2 |
摘要 | Objective: Caffeine is a central nervous system stimulant that can effectively alleviate brain fatigue and low cognitive efficiency induced by total sleep deprivation (TSD). Recent studies have demonstrated that caffeine can improve subjective attention and objective behavioral metrics, such as arousal level, reaction time, and memory efficiency. However, only a few studies have examined the electrophysiological changes caused by the caffeine in humans following sleep disturbance. In this study, an event-related potential (ERP) technique was employed to measure the behavioral, cognitive, and electrophysiological changes produced by caffeine administration after TSD. Methods: Sixteen healthy subjects within-subject design performed a visual Go/No-Go task with simultaneous electroencephalogram recording. Behavioral and ERP data were evaluated after 36 h of TSD, and the effects of ingestion of either 400 mg of caffeine or placebo were compared in a double-blind randomized design. Results: Compared with placebo administration, the Go hit rates were significantly enhanced in the caffeine condition. A simple effect analysis revealed that, compared with baseline, the Go-P2 amplitude was significantly enhanced after TSD in the caffeine consumption condition. A significant main effect of the drug was found on No-Go-P2, No-Go-N2 amplitude, and Go-P2 latency before and after TSD. Conclusion: Our findings indicate that caffeine administration has acute effects on improving the efficiency of individual automatic reactions and early cognitive processes. Caffeine was related to the preservation of an individual's arousal level and accelerated response-related decisions, while subjects' higher-level recognition had limited improvement with prolonged awareness. |
关键词 | caffeine ERP total sleep deprivation Go No-Go reaction time (RTs) |
2020-06-22 | |
语种 | 英语 |
DOI | 10.3389/fnbeh.2020.00108 |
发表期刊 | FRONTIERS IN BEHAVIORAL NEUROSCIENCE
![]() |
ISSN | 1662-5153 |
卷号 | 14页码:12 |
期刊论文类型 | article |
收录类别 | SCI |
资助项目 | National Military Science Foundation of China[BWS17J025] ; National Military Science Foundation of China[AWS14J011] ; National Military Science Foundation of China[AWS16J023] ; National Military Science Foundation of China[HZ18C01and Z161100002616019] |
出版者 | FRONTIERS MEDIA SA |
WOS关键词 | ATTENTION ; P300 ; MOOD ; TASK ; PAIN ; EEG |
WOS研究方向 | Behavioral Sciences ; Neurosciences & Neurology |
WOS类目 | Behavioral Sciences ; Neurosciences |
WOS记录号 | WOS:000553792200001 |
Q分类 | Q2 |
资助机构 | National Military Science Foundation of China |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.psych.ac.cn/handle/311026/32347 |
专题 | 中国科学院行为科学重点实验室 |
通讯作者 | Fan, Rong; Ma, Qiang |
作者单位 | 1.Tianjin Inst Environm & Operat Med, Dept Operat Med, Tianjin, Peoples R China 2.Chinese Acad Sci, Inst Psychol, Key Lab Behav Sci, Beijing, Peoples R China 3.Beijing Sport Univ, Sch Psychol, Beijing, Peoples R China 4.Xi Qing Hosp, Cent Lab, Tianjin, Peoples R China |
推荐引用方式 GB/T 7714 | Chen, Xuewei,Zhang, Liwei,Yang, Danfeng,et al. Effects of Caffeine on Event-Related Potentials and Neuropsychological Indices After Sleep Deprivation[J]. FRONTIERS IN BEHAVIORAL NEUROSCIENCE,2020,14:12. |
APA | Chen, Xuewei.,Zhang, Liwei.,Yang, Danfeng.,Li, Chao.,An, Gaihong.,...&Ma, Qiang.(2020).Effects of Caffeine on Event-Related Potentials and Neuropsychological Indices After Sleep Deprivation.FRONTIERS IN BEHAVIORAL NEUROSCIENCE,14,12. |
MLA | Chen, Xuewei,et al."Effects of Caffeine on Event-Related Potentials and Neuropsychological Indices After Sleep Deprivation".FRONTIERS IN BEHAVIORAL NEUROSCIENCE 14(2020):12. |
条目包含的文件 | ||||||
文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
Effects of Caffeine (2411KB) | 期刊论文 | 出版稿 | 限制开放 | CC BY-NC-SA | 请求全文 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论