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Dissociable fronto-striatal functional networks predict choice impulsivity | |
Wang, Qiang1,2,3; Lv, Chenyu4; He, Qinghua4,5; Xue, Gui6,7 | |
第一作者 | Wang, Qiang |
通讯作者邮箱 | qiang wang wangqiang113@gmail.com |
心理所单位排序 | 5 |
摘要 | Fronto-striatal structural connectivity is associated with choice impulsivity. Yet, to date, whether distinct fronto-striatal functional coupling associates with impulsive choices are largely unknown. Using seed-based resting-state functional MRI (rsfMRI) combined with multivariate pattern analysis (MVPA), the present study aimed to explore the predictions of dissociable frontal-striatal functional connectivity on choice impulsivity in a relatively large sample (N = 429). Adaptive delay-discounting task was utilized to assess choice impulsivity and the striatum was further divided into three subregions including the nucleus accumbens (NAcc), caudate, and putamen. Results revealed that both the functional coupling between the NAcc and the limbic/dorsolateral prefrontal cortex, and between the caudate and the dorsal prefrontal cortex, including the dorsomedial prefrontal cortex (DMPFC), successfully predicted the delay-discounting rate. However, such pattern was not observed in the putamen-prefrontal functional connectivity. These findings suggest fronto-striatal-dependent neural mechanisms of choice impulsivity and further provide a better understanding of the contributions of striatum subregions and their functional connectivities with different areas of prefrontal cortex upon inter-temporal choice. |
关键词 | Inter-temporal choice Multivariate pattern analysis Prefrontal cortex Choice impulsivity Striatum Functional connectivity |
2020-08-19 | |
语种 | 英语 |
DOI | 10.1007/s00429-020-02128-0 |
发表期刊 | BRAIN STRUCTURE & FUNCTION |
ISSN | 1863-2653 |
页码 | 10 |
期刊论文类型 | article |
收录类别 | SCI |
资助项目 | Humanities and Social Science Fund Project of the Ministry of Education[20YJC190018] ; National natural science foundation of China[31972906] ; open research fund of the key laboratory of mental health, Institute of Psychology, Chinese Academy of Sciences[KLMH2019K05] ; High-end Foreign expert introduction program[G20190022029] |
出版者 | SPRINGER HEIDELBERG |
WOS关键词 | PREFRONTAL CORTEX ; DECISION-MAKING ; SELF-CONTROL ; DELAY ; CONNECTIVITY ; REWARDS ; BRAIN ; IMMEDIATE ; TIME ; REPRESENTATION |
WOS研究方向 | Anatomy & Morphology ; Neurosciences & Neurology |
WOS类目 | Anatomy & Morphology ; Neurosciences |
WOS记录号 | WOS:000560985500003 |
Q分类 | Q1 |
资助机构 | Humanities and Social Science Fund Project of the Ministry of Education ; National natural science foundation of China ; open research fund of the key laboratory of mental health, Institute of Psychology, Chinese Academy of Sciences ; High-end Foreign expert introduction program |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.psych.ac.cn/handle/311026/32496 |
专题 | 中国科学院心理健康重点实验室 |
通讯作者 | Wang, Qiang; He, Qinghua; Xue, Gui |
作者单位 | 1.Tianjin Normal Univ, Acad Psychol & Behav, Key Res Base Humanities & Social Sci, Minist Educ, Tianjin 300387, Peoples R China 2.Tianjin Normal Univ, Fac Psychol, Tianjin 300387, Peoples R China 3.Tianjin Social Sci Lab Students Mental Dev & Lear, Tianjin 300387, Peoples R China 4.Southwest Univ, Fac Psychol, Chongqing 400715, Peoples R China 5.Inst Psychol, CAS Key Lab Mental Hlth, Beijing 100101, Peoples R China 6.Beijing Normal Univ, Natl Key Lab Cognit Neurosci & Learning, Beijing 100875, Peoples R China 7.Beijing Normal Univ, IDG McGovern Inst Brain Res, Beijing 100875, Peoples R China |
通讯作者单位 | 中国科学院心理健康重点实验室 |
推荐引用方式 GB/T 7714 | Wang, Qiang,Lv, Chenyu,He, Qinghua,et al. Dissociable fronto-striatal functional networks predict choice impulsivity[J]. BRAIN STRUCTURE & FUNCTION,2020:10. |
APA | Wang, Qiang,Lv, Chenyu,He, Qinghua,&Xue, Gui.(2020).Dissociable fronto-striatal functional networks predict choice impulsivity.BRAIN STRUCTURE & FUNCTION,10. |
MLA | Wang, Qiang,et al."Dissociable fronto-striatal functional networks predict choice impulsivity".BRAIN STRUCTURE & FUNCTION (2020):10. |
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