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Quality of Life in Patients With Methamphetamine Use Disorder: Relationship to Impulsivity and Drug Use Characteristics
Wang, Yingying1,2,3; Zuo, Jinsong4; Hao, Wei1,2,3; Shen, Hongxian1,2,3; Zhang, Xiaojie1,2,3; Deng, Qijian1,2,3; Liu, Mengqi1,2,3; Zhao, Zhiqiang5,6; Zhang, Lina1,2,3; Zhou, Yanan7; Li, Manyun1,2,3; Liu, Tieqiao1,2,3; Zhang, Xiangyang8
First AuthorWang, Yingying
Correspondent Emailiutieqiao123@csu.edu.cn (tieqiao liu ) ; zhangxy@psych.ac.cn (xiangyang zhang )
Contribution Rank8
Abstract

Background The quality of life (QOL) of patients with methamphetamine use disorder (MAUD) is increasingly recognized as an important outcome. Previous studies have found that impulsivity is negatively associated with QOL in mental disorders, but this relationship is rarely confirmed in patients with MAUD. We hypothesized that impulsivity is negatively correlated with QOL in patients with MAUD based on previous findings. In addition, a variety of drug use characteristics of patients that may potentially affect their QOL need to be further explored. Therefore, the purpose of this study was to explore the relationship between impulsivity, multiple drug use characteristics, and QOL in patients with MAUD. Methods A total of 379 patients with MAUD were recruited, and the majority of them were male (85.5%), with an average age of 33.93 +/- 7.08 years. Two psychiatrists conducted semi-structured interviews with methamphetamine (MA) users in two compulsory drug rehabilitation centers to obtain their demographics and drug use characteristics. The Barratt Impulsiveness Scale-11 (BIS-11) and Brief WHO Quality of Life Assessment (WHOQOL-BREF) were used to assess patients' impulsivity and QOL, respectively. Correlation and univariate regression analysis were used to explore the relationships between impulsivity, a series of drug use characteristics and patients' QOL in different domains. Further multiple linear regression analysis was used to identify what extent the above clinical variables explained the variations in patients' QOL. Results Age, marital status, employment, and various drug use characteristics were significantly associated with at least one QOL domain. Among them, married and full-time job were positively correlated with QOL, while others were negatively correlated with QOL. The total score of BIS-11 was significantly negatively correlated with all four domains of QOL. Impulsivity, a range of drug use characteristics and certain demographic characteristics collectively explained varying degrees of variation in different domains of QOL. Conclusions Impulsivity and various drug use characteristics can significantly predict QOL in all fields of MAUD patients. In addition, we have also found differences in the predictors of QOL in different domains. Overall, this study provides clinical guidance for the treatment of MAUD patients, that is, management of impulsivity in patients with MAUD may help improve their QOL and even sustain their drug rehabilitation.

Keywordmethamphetamine quality of life impulsivity substance use disorder drug abuse drug use
2020-09-30
Language英语
DOI10.3389/fpsyt.2020.579302
Source PublicationFRONTIERS IN PSYCHIATRY
ISSN1664-0640
Volume11Pages:8
Subtype实证研究
Indexed BySCI
Funding ProjectNational Key R&D Program of China[2017YFC1310400] ; National Natural Science Foundation of China[81371465] ; National Natural Science Foundation of China[81671324] ; provincial Natural Science Foundation of Hunan[2020JJ4795]
PublisherFRONTIERS MEDIA SA
WOS KeywordSUBSTANCE USE ; ADDICTION SEVERITY ; DUAL DIAGNOSIS ; SYMPTOMS ; COCAINE ; SEEKING ; PARTICIPANTS ; INDIVIDUALS ; ABSTINENCE ; PATTERNS
WOS Research AreaPsychiatry
WOS SubjectPsychiatry
WOS IDWOS:000577615500001
Citation statistics
Document Type期刊论文
Identifierhttp://ir.psych.ac.cn/handle/311026/32965
Collection中国科学院心理健康重点实验室
Corresponding AuthorLiu, Tieqiao; Zhang, Xiangyang
Affiliation1.Cent South Univ, Xiangya Hosp 2, Natl Clin Res Ctr Mental Disorders, Changsha, Peoples R China
2.Cent South Univ, Xiangya Hosp 2, Hunan Key Lab Psychiat & Mental Hlth,Inst Mental, Dept Psychiat,China Natl Technol Inst Mental Diso, Changsha, Peoples R China
3.Cent South Univ, Xiangya Hosp 2, Hunan Med Ctr Mental Hlth, Changsha, Peoples R China
4.Hunan Univ Technol, Coll Life Sci & Chem, Zhuzhou, Peoples R China
5.Xinjiang Mental Hlth Ctr, Dept Med Addict, Urumqi, Peoples R China
6.Urumqi Fourth Peoples Hosp, Urumqi, Peoples R China
7.Brains Hosp Hunan Prov, Dept Psychiat, Changsha, Peoples R China
8.Chinese Acad Sci, Inst Psychol, CAS Key Lab Mental Hlth, Beijing, Peoples R China
Corresponding Author AffilicationKey Laboratory of Mental Health, CAS
Recommended Citation
GB/T 7714
Wang, Yingying,Zuo, Jinsong,Hao, Wei,et al. Quality of Life in Patients With Methamphetamine Use Disorder: Relationship to Impulsivity and Drug Use Characteristics[J]. FRONTIERS IN PSYCHIATRY,2020,11:8.
APA Wang, Yingying.,Zuo, Jinsong.,Hao, Wei.,Shen, Hongxian.,Zhang, Xiaojie.,...&Zhang, Xiangyang.(2020).Quality of Life in Patients With Methamphetamine Use Disorder: Relationship to Impulsivity and Drug Use Characteristics.FRONTIERS IN PSYCHIATRY,11,8.
MLA Wang, Yingying,et al."Quality of Life in Patients With Methamphetamine Use Disorder: Relationship to Impulsivity and Drug Use Characteristics".FRONTIERS IN PSYCHIATRY 11(2020):8.
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