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动物前注意加工模型的建立及评价:基于精神类疾病损伤
Alternative TitleEstablishment and evaluation of animal pre-attentive processing models: Based on the MMN deficit in mental disorders
王盛; 陈雅弘; 王锦琰
First Author王盛
Correspondent Emailwangjy@psych.ac.cn (王锦琰)
Contribution Rank1
Abstract

前注意加工(pre-attentive processing)是无需注意参与的,对刺激的早期、自动化的加工,而听觉失匹配负波(mismatchnegativity,MMN)是研究前注意加工最常用的指标。很多精神疾病发现MMN损伤,但对MMN损伤的神经生物学机制了解甚少,动物模型具有成熟的神经生物学和药理学操作,可以帮助理解MMN潜在机制。未来动物研究中应考虑到动物特性,结合人类和动物研究优势开展跨物种研究,以便更深入的了解前注意加工的微观和宏观表现。

Other Abstract

Pre-attentive processing refers to the early and automatic cognitive processes which are independent of consciousness and do not demand attention. Auditory mismatch negativity (MMN) is the most commonly used indicator of pre-attentive processing. MMN deficits have been found in a various of mental disorders, but little is known about the neurobiological mechanisms of MMN deficits. Combined with highly developed neurobiological and pharmacological techniques, animal models can provide valuable insights into the underlying mechanisms of MMN. Future animal studies of MMN should give more thoughts to the biological characteristics of different species and compare MMN across species in combination with human and animal research advantages. Hopefully, this comparative approach will lead to a better understanding of pre-attentive processing at both the macro and the micro levels.

Keyword啮齿类动物 前注意加工 失匹配负波 精神分裂症
2020
Language中文
DOI10.3724/SP.J.1042.2020.02027
Source Publication心理科学进展
ISSN1671-3710
Volume28Issue:12Pages:2027-2039
Subtype实证研究
Indexed ByCSCD
Project Intro.

国家自然科学基金项目(31271092)

CSCD IDCSCD:6856723
Citation statistics
Document Type期刊论文
Identifierhttp://ir.psych.ac.cn/handle/311026/33349
Collection中国科学院心理健康重点实验室
Affiliation1.中国科学院心理健康重点实验室(中国科学院心理研究所)
2.中国科学院大学心理学系
Recommended Citation
GB/T 7714
王盛,陈雅弘,王锦琰. 动物前注意加工模型的建立及评价:基于精神类疾病损伤[J]. 心理科学进展,2020,28(12):2027-2039.
APA 王盛,陈雅弘,&王锦琰.(2020).动物前注意加工模型的建立及评价:基于精神类疾病损伤.心理科学进展,28(12),2027-2039.
MLA 王盛,et al."动物前注意加工模型的建立及评价:基于精神类疾病损伤".心理科学进展 28.12(2020):2027-2039.
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