Effects of Sleep Deprivation on Working Memory: Change in Functional Connectivity Between the Dorsal Attention, Default Mode, and Fronto-Parietal Networks | |
Dai, Cimin1; Zhang, Ying2; Cai, Xiaoping3; Peng, Ziyi1; Zhang, Liwei4; Shao, Yongcong1,5; Wang, Cuifeng6 | |
第一作者 | Dai, Cimin |
通讯作者邮箱 | budeshao@aliyun.com (yongcong shao ) ; 15275228256@163.com (cuifeng wang ) |
心理所单位排序 | 4 |
摘要 | Sleep deprivation (SD) is very common in modern society and has a profound effect on cognitive function, in particular on working memory (WM). This type of memory is required for completion of many tasks and is adversely affected by SD. However, the cognitive neural mechanism by which SD affects WM, remains unclear. In this study, we investigated the changes in the brain network involved in WM after SD. Twenty-two healthy subjects underwent functional magnetic resonance imaging scan while in a state of resting wakefulness and again after 36 h of total SD and performed a WM task before each scanning session. Nineteen main nodes of the default mode network (DMN), dorsal attention network (DAN), fronto-parietal network (FPN), salience network (SN), and other networks were selected for functional analysis of brain network connections. Functional connectivity measures were computed between seed areas for region of interest (ROI)-to-ROI analysis and to identify patterns of ROI-to-ROI connectivity. The relationship between the significant changes in functional connectivity in the brain network and WM performance were then examined by Pearson's correlation analysis. WM performance declined significantly after SD. Compared with the awake state, the functional connectivity between DAN and DMN significantly increased after SD while that between FPN and DMN significantly decreased. Correlation analysis showed that the enhanced functional connectivity between DAN and DMN was negatively correlated with the decline in WM performance and that the decline in functional connectivity between FPN and DMN was positively correlated with decreased WM performance. These findings suggested that SD may affect WM by altering the functional connectivity among DMN, DAN, and FPN. |
关键词 | sleep deprivation working memory functional connectivity brain network fMRI |
2020-10-12 | |
语种 | 英语 |
DOI | 10.3389/fnhum.2020.00360 |
发表期刊 | FRONTIERS IN HUMAN NEUROSCIENCE |
ISSN | 1662-5161 |
卷号 | 14页码:12 |
期刊论文类型 | 实证研究 |
收录类别 | SCI |
资助项目 | National Science Foundation of Winter Olympics Technology Plan of China[2019YFF0301600] ; National Science and Technology Commission Project[2019JCJQZD119] |
出版者 | FRONTIERS MEDIA SA |
WOS关键词 | DORSOLATERAL PREFRONTAL CORTEX ; EVENT-RELATED POTENTIALS ; BRAIN ACTIVITY ; RESTING BRAIN ; METAANALYSIS ; ACTIVATION ; RETRIEVAL ; CINGULATE ; COMPONENT ; DYNAMICS |
WOS研究方向 | Neurosciences & Neurology ; Psychology |
WOS类目 | Neurosciences ; Psychology |
WOS记录号 | WOS:000583632100001 |
资助机构 | National Science Foundation of Winter Olympics Technology Plan of China ; National Science and Technology Commission Project |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.psych.ac.cn/handle/311026/33378 |
专题 | 健康与遗传心理学研究室 |
通讯作者 | Shao, Yongcong; Wang, Cuifeng |
作者单位 | 1.Beijing Sport Univ, Sch Psychol, Beijing, Peoples R China 2.Gen Hosp Peoples Liberat Army, Med Ctr 8, Beijing, Peoples R China 3.Gen Hosp Peoples Liberat Army, Dept Cadraword, Div 3, Beijing, Peoples R China 4.Chinese Acad Sci, Inst Psychol, Beijing, Peoples R China 5.Chinese Acad Sci, Suzhou Inst Biomed Engn & Techol, Suzhou, Peoples R China 6.Qingdao Huangdao Peoples Hosp, Dept Resp Med, Qingdao, Peoples R China |
推荐引用方式 GB/T 7714 | Dai, Cimin,Zhang, Ying,Cai, Xiaoping,et al. Effects of Sleep Deprivation on Working Memory: Change in Functional Connectivity Between the Dorsal Attention, Default Mode, and Fronto-Parietal Networks[J]. FRONTIERS IN HUMAN NEUROSCIENCE,2020,14:12. |
APA | Dai, Cimin.,Zhang, Ying.,Cai, Xiaoping.,Peng, Ziyi.,Zhang, Liwei.,...&Wang, Cuifeng.(2020).Effects of Sleep Deprivation on Working Memory: Change in Functional Connectivity Between the Dorsal Attention, Default Mode, and Fronto-Parietal Networks.FRONTIERS IN HUMAN NEUROSCIENCE,14,12. |
MLA | Dai, Cimin,et al."Effects of Sleep Deprivation on Working Memory: Change in Functional Connectivity Between the Dorsal Attention, Default Mode, and Fronto-Parietal Networks".FRONTIERS IN HUMAN NEUROSCIENCE 14(2020):12. |
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