Institutional Repository of Key Laboratory of Mental Health, CAS
Magnetic resonance imaging for chronic pain: diagnosis, manipulation, and biomarkers | |
Tu, Yiheng1,2; Cao, Jin3,4; Bi, Yanzhi1,2; Hu, Li1,2,5 | |
第一作者 | Tu, Yiheng |
通讯作者邮箱 | huli@psych.ac.cn |
心理所单位排序 | 1 |
摘要 | Pain is a multidimensional subjective experience with biological, psychological, and social factors. Whereas acute pain can be a warning signal for the body to avoid excessive injury, long-term and ongoing pain may be developed as chronic pain. There are more than 100 million people in China living with chronic pain, which has raised a huge socioeconomic burden. Studying the mechanisms of pain and developing effective analgesia approaches are important for basic and clinical research. Recently, with the development of brain imaging and data analytical approaches, the neural mechanisms of chronic pain have been widely studied. In the first part of this review, we briefly introduced the magnetic resonance imaging and conventional analytical approaches for brain imaging data. Then, we reviewed brain alterations caused by several chronic pain disorders, including localized and widespread primary pain, primary headaches and orofacial pain, musculoskeletal pain, and neuropathic pain, and present meta-analytical results to show brain regions associated with the pathophysiology of chronic pain. Next, we reviewed brain changes induced by pain interventions, such as pharmacotherapy, neuromodulation, and acupuncture. Lastly, we reviewed emerging studies that combined advanced machine learning and neuroimaging techniques to identify diagnostic, prognostic, and predictive biomarkers in chronic pain patients. |
关键词 | chronic pain magnetic resonance imaging biomarkers machine learning |
2020-11-23 | |
语种 | 英语 |
DOI | 10.1007/s11427-020-1822-4 |
发表期刊 | SCIENCE CHINA-LIFE SCIENCES |
ISSN | 1674-7305 |
页码 | 18 |
期刊论文类型 | 实证研究 |
收录类别 | SCI |
资助项目 | National Natural Science Foundation of China[32071061] ; National Natural Science Foundation of China[31822025] ; National Natural Science Foundation of China[31671141] ; National Natural Science Foundation of China[31800926] ; Scientific Foundation of Institute of Psychology, Chinese Academy of Sciences[E0CX521003] |
出版者 | SCIENCE PRESS |
WOS关键词 | DYNAMIC FUNCTIONAL CONNECTIVITY ; INTRINSIC BRAIN CONNECTIVITY ; DIRECT-CURRENT STIMULATION ; LOW-BACK-PAIN ; RIGHT FRONTOPARIETAL NETWORK ; RESTING-STATE CONNECTIVITY ; CHRONIC PELVIC PAIN ; WHITE-MATTER ; DOUBLE-BLIND ; FIBROMYALGIA PATIENTS |
WOS研究方向 | Life Sciences & Biomedicine - Other Topics |
WOS类目 | Biology |
WOS记录号 | WOS:000593842100002 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.psych.ac.cn/handle/311026/33445 |
专题 | 中国科学院心理健康重点实验室 中国科学院心理研究所 |
通讯作者 | Hu, Li |
作者单位 | 1.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China 2.Univ Chinese Acad Sci, Dept Psychol, Beijing 100101, Peoples R China 3.Massachusetts Gen Hosp, Dept Psychiat, Boston, MA 02129 USA 4.Harvard Med Sch, Boston, MA 02129 USA 5.Guangzhou Med Univ, Affiliated Hosp 2, State Key Clin Specialty Pain Med, Dept Pain Management, Guangzhou 510260, Peoples R China |
第一作者单位 | 中国科学院心理健康重点实验室 |
通讯作者单位 | 中国科学院心理健康重点实验室 |
推荐引用方式 GB/T 7714 | Tu, Yiheng,Cao, Jin,Bi, Yanzhi,et al. Magnetic resonance imaging for chronic pain: diagnosis, manipulation, and biomarkers[J]. SCIENCE CHINA-LIFE SCIENCES,2020:18. |
APA | Tu, Yiheng,Cao, Jin,Bi, Yanzhi,&Hu, Li.(2020).Magnetic resonance imaging for chronic pain: diagnosis, manipulation, and biomarkers.SCIENCE CHINA-LIFE SCIENCES,18. |
MLA | Tu, Yiheng,et al."Magnetic resonance imaging for chronic pain: diagnosis, manipulation, and biomarkers".SCIENCE CHINA-LIFE SCIENCES (2020):18. |
条目包含的文件 | ||||||
文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
Magnetic resonance i(2350KB) | 期刊论文 | 出版稿 | 限制开放 | CC BY-NC-SA | 请求全文 |
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