中国科学院心理健康重点实验室知识库

目的 探讨阻塞性睡眠呼吸暂停低通气综合征(OSAHS) 患者正念水平与负性情绪的关系以及正念水平在睡眠呼吸暂停指数(AHI) 与体重指数(BMI) 和颈围之间的中介作用。方法 选取2016 年5 月至2017 年8 月在

解放军总医院睡眠医学研究中心就诊的OSAHS 患者130 例，根据AHI 将患者分为轻度42 例、中度43 例和重度45 例。记录患者一般资料，采用便携式睡眠仪(PM) 监测患者AHI、夜间最低血氧饱和度(LSaO2) 及夜间平均血氧饱和度(MSaO2)，并进行抑郁焦虑压力量表(DASS)、正念注意觉知量表(MAAS) 评分。结果 OSAHS 患者随着病情程度加重，DASS 各维度得分升高，MAAS 得分减少。重度组OSAHS 患者MAAS 得分为(36.78±10.76)，低于中度(53.26±9.18) 和轻度组(69.45±11.21)。重度组DASS 各维度得分(23.44±8.599)、(26.22±7.65)、(24.51±8.30) 高于中、轻度组[(13.47±4.53)、(15.19±4.79)、(14.37±5.86)]、[(5.83±4.52)、(7.45±5.26)、(7.05±5.25)]，差异均有统计学意义(P <0.05)。MAAS 在AHI 与BMI 和颈围之间具有完全中介效应，中介效应占总效应41.1%、43.4%。结论 在OSAHS 患者中，重度OSAHS 患者的正念水平低于中、轻度患者，焦虑抑郁压力水平高于中、轻度患者。正念水平在AHI 与BMI、颈围之间具有中介效应。

Objective To investigate the relationship between mindfulness level and negative emotion in patients with obstructive sleep apnea hypopnea syndrome (OSAHS), and the mediating role of mindfulness level in the sleep apnea index (AHI) with body mass index (BMI) and neck circumference. Methods Totally 130 patients with OSAHS were divided into 3 groups, mild (n=42), moderate (n=43) and severe (n=45). Records of general information of patients and use the portable sleep monitor (PM) to detect patients' AHI, lowest nocturnal oxygen saturation (LSaO2) and mean nocturnal oxygen saturation (MSaO2), and the Depression Anxiety Stress Scale (DASS), Mindful attention Awareness Scale (MAAS ) were used to score. Results In patients with OSAHS, the DASS scores increased and MAAS scores decreased with the severity of the disease. The MAAS score of OSAHS in severe group was lower than that in moderate and mild group (36.78 ±10.76), (53.26±9.18), and (69.45±11.21). The scores of DASS in severe group (23.44±8.60), (26.22±7.65), (24.51±8.30) were higher than those in medium and mild groups [(13.47±4.53), (15.19±4.79), (14.37±5.86)], [(5.83±4.52), (7.45±5.26), (7.05±5.25)], and the difference was statistically significant (P<0.05). MAAS had a complete mediating effect between AHI and BMI and neck circumference, and the mediating effect accounted for 41.1% and 43.4% of the total effect. Conclusion In patients with OSAHS, the level of mindfulness of patients with severe OSAHS is lower than that of mild and moderate patients. The level of anxiety, depression and stress is higher than that of moderate or mild patients. Mindfulness level has a mediating effect between AHI and BMI and neck circumference.

北京科技计划项目(D151100002315003)