重度感音神经性聋患者助听时前注意加工的特征

doi:10. 3969/j. issn. 1006-7299. 2010. 03. 012

PSYCH OpenIR > 中国科学院心理研究所回溯数据库(1956-2010)

	重度感音神经性聋患者助听时前注意加工的特征
其他题名	The Characteristics of the Pre--attentive Process in Severe Sensorineural Hearing Loss Patients with Hearing Aids
	王晓翠 1; 许贵芳2 ; 刘莎 1; 鲜军舫 1; 王振常 2; 莫玲燕 1; 郭连生 1; 杨宜林 1
第一作者	王晓翠
通讯作者邮箱	liusha_ls@sohu. com (刘莎)
心理所单位排序	2
摘要	目的以失匹配负波（mismatch negativity,MMN）为指标,初步研究声场下重度感音神经性聋患者助听时前注意加工的特征.方法对14例重度感音神经性聋患者（助听器组）和18例听力正常者（对照组）,应用美国64导Neuroscan EEG/ERP记录系统,采用经典的Oddball模式,标准刺激和偏差刺激分别为1 000 Hz和1 100 Hz的短纯音,分别测试两组声场下MMN,分析两组MMN的峰潜伏期、开始时间、结束时间、持续时间、峰值波幅和61～240 ms时程内每20 ms的平均波幅.结果助听器组有12例检出MMN,检出率为85.71%（12/14）;对照组检出率为100%.对照组MMN开始时间的平均值为93.06±12.26 ms,助听器组为122.17±32.36ms,助听器组明显比对照组晚（P〈0.05）;对照组结束时间的平均值为233.44±13.20 ms,助听器组为192.08±46.10 ms,助听器组明显比对照组早（P〈0.05）;对照组MMN持续时间的平均值为140.38±61.78 ms,助听器组为69.92±52.08 ms,助听器组明显比对照组短（P〈0.05）;对照组161～240 ms时程内MMN的平均波幅为-1.20μV,助听器组为0.12μV,助听器组明显比对照组降低（P〈0.05）;两组61～160 ms时程内MMN平均波幅、MMN峰潜伏期、峰值波幅的差异无统计学意义（P〉0.05）.结论重度感音神经性聋患者助听时可在前注意加工阶段对声音的频率进行加工,与听力正常人相比,助听器组MMN波形的开始时间明显延迟,而结束时间提前,导致MMN波形的持续时间明显缩短,161~240 ms时程内的平均波幅明显降低.
其他摘要	Objective Mismatch negativity（MMN）, as index, was used to study the characteristics of the pre --attentive process in severe sensorineural hearing loss patients with hearing aids. Methods Two groups were tested：one group of 14 severe sensorineural hearing loss patients as the hearing aids group while the other had 20 control subjects with normal hearing named as control group. Event--related potentials were recorded from 64 electrodes Neuroscan EEG/ERP system using a passive oddball paradigm in free field. The standard-- tone frequency was 1 000 Hz, and the deviant--tone frequency was 1 100 Hz. The onset time,offset time,peak latency,duration and mean amplitudes in 61-240 ms of the two groups were observed. Results MMN could be recorded in 12 amplified patients and 18 control subjects. The mean on set time of control group was 93.06±12.26 ms and the hearing aids group was 122.17±32.36 ms, significantly delayed than control group（P〈0.05）. The mean off set time of control group was 233.44±13. 2 ms and the hearing aids group was 192. 08 ms, significantly earlier than control group （P〈0. 05）; the mean duration of control group was 140.38 ms and the hearing aids group was 69.92 ms, significantly shorter than control group（P〈0. 05）. The mean amplitude of control group in 161-240 ms was -1.20 μV and the hearing aids group was 0.12 μV,significantly decreased in mean amplitude（P〈0.05）. No statistically significant differences were observed in the peck latency,peak amplitude and mean amplitude in 61-160 ms between the two groups （P〉0.05）. Conclusion Severe sensorineural hearing loss patients with hearing aids could process frequency in the pre--attentive stage. The use of hearing aids substantially improved the detectability of MMN. Compared with control group, the hearing aids group had significantly prolonged onset time, shortening offset time, short duration and decreased mean amplitude in 161-240 ms.
关键词	感音神经性聋失匹配负波前注意加工助听器
	2010
语种	中文
DOI	10. 3969/j. issn. 1006-7299. 2010. 03. 012
发表期刊	听力学及言语疾病杂志
ISSN	1006-7299
卷号	18.0 期号:003 页码:239-242
期刊论文类型	实证研究
收录类别	CSCD
项目简介	国家自然科学基金(30371533)、国家自然科学基金(30872859) 北京市自然科学基金(7062019)、北京市自然科学基金(7082026) 北京市教育委员会科技发展计划面上项目(KM200710025020) 高等学校博士学科点专项科研基金(20060025002) 北京市科技新星计划(B类2004-B-31)联合资助
CSCD记录号	CSCD:3877488
引用统计
文献类型	期刊论文
条目标识符	https://ir.psych.ac.cn/handle/311026/36173
专题	中国科学院心理研究所回溯数据库(1956-2010)
作者单位	1.首都医科大学 2.中国科学院心理研究所
推荐引用方式 GB/T 7714	王晓翠,许贵芳,刘莎,等. 重度感音神经性聋患者助听时前注意加工的特征[J]. 听力学及言语疾病杂志,2010,18.0(003):239-242.
APA	王晓翠.,许贵芳.,刘莎.,鲜军舫.,王振常.,...&杨宜林.(2010).重度感音神经性聋患者助听时前注意加工的特征.听力学及言语疾病杂志,18.0(003),239-242.
MLA	王晓翠,et al."重度感音神经性聋患者助听时前注意加工的特征".听力学及言语疾病杂志 18.0.003(2010):239-242.