PSYCH OpenIR  > 中国科学院心理健康重点实验室
Neural Correlates of Audiovisual Temporal Binding Window in Individuals With Schizotypal and Autistic Traits: Evidence From Resting-State Functional Connectivity
Zhou, Han-yu1,2; Wang, Yong-ming1,2; Zhang, Rui-ting1,2; Cheung, Eric F. C.3; Pantelis, Christos4,5,6; Chan, Raymond C. K.1,2
Corresponding AuthorChan, Raymond C. K.(rckchan@psych.ac.cn)
AbstractTemporal proximity is an important clue for multisensory integration. Previous evidence indicates that individuals with autism and schizophrenia are more likely to integrate multisensory inputs over a longer temporal binding window (TBW). However, whether such deficits in audiovisual temporal integration extend to subclinical populations with high schizotypal and autistic traits are unclear. Using audiovisual simultaneity judgment (SJ) tasks for nonspeech and speech stimuli, our results suggested that the width of the audiovisual TBW was not significantly correlated with self-reported schizotypal and autistic traits in a group of young adults. Functional magnetic resonance imaging (fMRI) resting-state activity was also acquired to explore the neural correlates underlying inter-individual variability of TBW width. Across the entire sample, stronger resting-state functional connectivity (rsFC) between the left superior temporal cortex and the left precuneus, and weaker rsFC between the left cerebellum and the right dorsal lateral prefrontal cortex were correlated with a narrower TBW for speech stimuli. Meanwhile, stronger rsFC between the left anterior superior temporal gyrus and the right inferior temporal gyrus was correlated with a wider audiovisual TBW for non-speech stimuli. The TBW-related rsFC was not affected by levels of subclinical traits. In conclusion, this study indicates that audiovisual temporal processing may not be affected by autistic and schizotypal traits and rsFC between brain regions responding to multisensory information and timing may account for the inter-individual difference in TBW width. Lay summary Individuals with ASD and schizophrenia are more likely to perceive asynchronous auditory and visual events as occurring simultaneously even if they are well separated in time. We investigated whether similar difficulties in audiovisual temporal processing were present in subclinical populations with high autistic and schizotypal traits. We found that the ability to detect audiovisual asynchrony was not affected by different levels of autistic and schizotypal traits. We also found that connectivity of some brain regions engaging in multisensory and timing tasks might explain an individual's tendency to bind multisensory information within a wide or narrow time window.
Keywordtemporal binding window audiovisual resting‐ state functional connectivity schizotypal traits autistic traits
2020-12-14
Language英语
DOI10.1002/aur.2456
Source PublicationAUTISM RESEARCH
ISSN1939-3792
Pages13
Indexed BySCI
Funding ProjectNational Key Research and Development Program[2016YFC0906402] ; National Science Foundation China[31970997] ; CAS Key Laboratory of Mental Health, the Institute of Psychology ; NHMRC Senior Principal Research Fellowship[1105825]
PublisherWILEY
WOS KeywordMULTISENSORY INTEGRATION ; PREFRONTAL CORTEX ; BRAIN ACTIVITY ; NETWORK ; SCHIZOPHRENIA ; INFORMATION ; SENSITIVITY ; PERFORMANCE ; PERCEPTION ; SYNCHRONY
WOS Research AreaBehavioral Sciences ; Psychology
WOS SubjectBehavioral Sciences ; Psychology, Developmental
WOS IDWOS:000598289100001
Citation statistics
Document Type期刊论文
Identifierhttp://ir.psych.ac.cn/handle/311026/38201
Collection中国科学院心理健康重点实验室
Corresponding AuthorChan, Raymond C. K.
Affiliation1.Chinese Acad Sci, Inst Psychol, CAS Key Lab Mental Hlth, Neuropsychol & Appl Cognit Neurosci Lab, Beijing, Peoples R China
2.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China
3.Castle Peak Hosp, Hong Kong, Peoples R China
4.Univ Melbourne, Dept Psychiat, Melbourne Neuropsychiat Ctr, Carlton, Vic, Australia
5.Melbourne Hlth, Carlton, Vic, Australia
6.Florey Inst Neurosci & Mental Hlth, Parkville, Vic, Australia
First Author Affilication认知与发展心理学研究室
Corresponding Author Affilication认知与发展心理学研究室
Recommended Citation
GB/T 7714
Zhou, Han-yu,Wang, Yong-ming,Zhang, Rui-ting,et al. Neural Correlates of Audiovisual Temporal Binding Window in Individuals With Schizotypal and Autistic Traits: Evidence From Resting-State Functional Connectivity[J]. AUTISM RESEARCH,2020:13.
APA Zhou, Han-yu,Wang, Yong-ming,Zhang, Rui-ting,Cheung, Eric F. C.,Pantelis, Christos,&Chan, Raymond C. K..(2020).Neural Correlates of Audiovisual Temporal Binding Window in Individuals With Schizotypal and Autistic Traits: Evidence From Resting-State Functional Connectivity.AUTISM RESEARCH,13.
MLA Zhou, Han-yu,et al."Neural Correlates of Audiovisual Temporal Binding Window in Individuals With Schizotypal and Autistic Traits: Evidence From Resting-State Functional Connectivity".AUTISM RESEARCH (2020):13.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Zhou, Han-yu]'s Articles
[Wang, Yong-ming]'s Articles
[Zhang, Rui-ting]'s Articles
Baidu academic
Similar articles in Baidu academic
[Zhou, Han-yu]'s Articles
[Wang, Yong-ming]'s Articles
[Zhang, Rui-ting]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Zhou, Han-yu]'s Articles
[Wang, Yong-ming]'s Articles
[Zhang, Rui-ting]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.