Institutional Repository of Key Laboratory of Mental Health, CAS
Diabetes in late-life schizophrenia: Prevalence, factors, and association with clinical symptoms | |
Huo, Lijuan1,4; Lu, Xiaobing1,4; Wu, Fengchun1,4; Huang, Xingbing1,4; Ning, Yuping1,3,4; Zhang, Xiang Yang2 | |
第一作者 | Huo, Lijuan |
通讯作者邮箱 | ningjeny@126.com (y. ning) ; zhangxy@psych.ac.cn (x.y. zhang) |
心理所单位排序 | 2 |
摘要 | Objective: The prevalence of diabetes mellitus has been found to be higher in patients with schizophrenia. Older patients are the fastest-growing segment of the schizophrenia population. However, few studies have explored diabetes in older patients with schizophrenia. Therefore, this study aimed to determine the prevalence and characteristics of factors associated with diabetes in Chinese patients with late-life schizophrenia (LLS), which has not been reported in previous studies. Methods: A total of 289 inpatients aged 60 or above who met the DSM-IV criteria for schizophrenia were recruited. The severity of psychopathology was assessed by the Positive and Negative Syndrome Scale (PANSS). Diabetes was diagnosed by fasting blood glucose tests, or oral glucose tolerance tests. Results: The overall prevalence of diabetes in LLS patients was 25.3%. The prevalence of diabetes in female patients was significantly higher than that in male patients (35% vs. 21.53%). Other factors associated with diabetes included higher BMI, greater waistline (only for males), higher levels of triglyceride, and more severe positive symptoms. Conclusion: These results indicate that the prevalence of diabetes in LLS patients is similar to that in the age matched general population. Female gender, excess weight and abdominal obesity, dyslipidemia, and clinical symptoms can be potential risk factors of diabetes in the LLS patient group. |
关键词 | Late-life schizophrenia Diabetes Prevalence Factors |
2021 | |
DOI | 10.1016/j.jpsychires.2020.09.026 |
发表期刊 | JOURNAL OF PSYCHIATRIC RESEARCH |
ISSN | 0022-3956 |
卷号 | 132页码:44-49 |
期刊论文类型 | 实证研究 |
收录类别 | SCI |
资助项目 | Science and Technology Plan Project of Guangdong Province[2019B030316001] ; Guangzhou Municipal Psychiatric Disease Clinical Transformation Laboratory, Science and Technology Program of Guangzhou, China[201805010009] ; Guangzhou municipal key discipline in medicine (2017-2019) ; National Natural Science Foundation of China (NSFC)[31771074] ; Science and Technology Program of Guangzhou[201807010064] ; Science and Technology Program of Guangzhou[201704020168] ; Science and Technology Program of Guangzhou[201804010259] ; Scientific research project of traditional Chinese medicine of Guangdong[20192070] ; science and technology project of Liwan district[201804011] |
出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
WOS研究方向 | Psychiatry |
WOS类目 | Psychiatry |
WOS记录号 | WOS:000598560300008 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.psych.ac.cn/handle/311026/38298 |
专题 | 中国科学院心理健康重点实验室 |
通讯作者 | Ning, Yuping; Zhang, Xiang Yang |
作者单位 | 1.Guangzhou Med Univ, Guangzhou Huiai Hosp, Affiliated Brain Hosp, Dept Psychiat, 36 Mingxin Rd, Guangzhou 510000, Peoples R China 2.Chinese Acad Sci, Inst Psychol, CAS Key Lab Mental Hlth, Guangzhou 100101, Peoples R China 3.Southern Med Univ, Sch Clin Med 1, Guangzhou 510000, Peoples R China 4.Guangdong Engn Technol Res Ctr Translat Med Menta, Guangzhou 510000, Peoples R China |
推荐引用方式 GB/T 7714 | Huo, Lijuan,Lu, Xiaobing,Wu, Fengchun,et al. Diabetes in late-life schizophrenia: Prevalence, factors, and association with clinical symptoms[J]. JOURNAL OF PSYCHIATRIC RESEARCH,2021,132:44-49. |
APA | Huo, Lijuan,Lu, Xiaobing,Wu, Fengchun,Huang, Xingbing,Ning, Yuping,&Zhang, Xiang Yang.(2021).Diabetes in late-life schizophrenia: Prevalence, factors, and association with clinical symptoms.JOURNAL OF PSYCHIATRIC RESEARCH,132,44-49. |
MLA | Huo, Lijuan,et al."Diabetes in late-life schizophrenia: Prevalence, factors, and association with clinical symptoms".JOURNAL OF PSYCHIATRIC RESEARCH 132(2021):44-49. |
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