PSYCH OpenIR  > 中国科学院心理研究所回溯数据库(1956-2010)
精神分裂症的潜伏抑制动物模型
Alternative TitleLatent Inhibition as an Animal Model of Schizophrenia
邵枫; 王玮文; 刘美; 金暕
2008
Source Publication心理科学进展
ISSN1671-3710
Volume16Issue:3Pages:392-398
Abstract精神分裂症动物模型的建立,是当前研究精神分裂症的神经生物学机制以及开发新的抗精神病药物的一个重要课题。文章系统地阐述了以潜伏抑制为行为模式的精神分裂症动物模型的理论以及神经机制,并重点介绍了精神分裂症的潜伏抑制动物模型的建立方法,包括(1)调节某些与精神分裂症相关的中枢神经递质的传递活动; (2)对与精神分裂症有关的中脑-伏隔核神经环路进行结构损伤或药物性干预; (3)在发育早期给予免疫刺激或环境应激。
Keyword精神分裂症动物模型 潜伏抑制 中脑-伏隔核神经环路
Subject Area变态心理学
Indexed By中文核心期刊要目总览 ASPT来源刊 CJFD收录刊
Language中文
Funding Project国家自然科学基金项目(批准号30670708,30500158);; 中国科学院重要方向项目(KSCX2-YW-R-131);; 国家基础研究(973)项目(2007CB512306)资助
NoteEstablishment of animal models of schizophrenia was critical for both understanding the mechanisms underlying this severe mental disease and developing new antipsychotics. This review thoroughly described the theory and neural substrate of the latent inhibition model of schizophrenia. The main methods for inducing latent inhibition abnormality in experimental animals included (1) modulations of neurotransmissions that were closely associated with schizophrenia, (2) focal lesions or pharmacological manipulat...
Document Type期刊论文
Identifierhttp://ir.psych.ac.cn/handle/311026/3848
Collection中国科学院心理研究所回溯数据库(1956-2010)
Corresponding Author邵枫
Recommended Citation
GB/T 7714
邵枫,王玮文,刘美,等. 精神分裂症的潜伏抑制动物模型[J]. 心理科学进展,2008,16(3):392-398.
APA 邵枫,王玮文,刘美,&金暕.(2008).精神分裂症的潜伏抑制动物模型.心理科学进展,16(3),392-398.
MLA 邵枫,et al."精神分裂症的潜伏抑制动物模型".心理科学进展 16.3(2008):392-398.
Files in This Item:
File Name/Size DocType Version Access License
精神分裂症的潜伏抑制动物模型.pdf(774KB) 限制开放--View Application Full Text
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[邵枫]'s Articles
[王玮文]'s Articles
[刘美]'s Articles
Baidu academic
Similar articles in Baidu academic
[邵枫]'s Articles
[王玮文]'s Articles
[刘美]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[邵枫]'s Articles
[王玮文]'s Articles
[刘美]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: 精神分裂症的潜伏抑制动物模型.pdf
Format: Adobe PDF
This file does not support browsing at this time
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.