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Dissociation of proactive and reactive cognitive control in individuals with schizotypy: an event-related potential study
Jia, Lu-xia1,2; Qin, Xiao-jing1,2; Cui, Ji-fang3; Shi, Hai-song4; Ye, Jun-yan1,2; Yang, Tian-xiao1,2; Wang, Ya1,2; Chan, Raymond CK1,2
First AuthorJia, Lu-xia
Correspondent Emailwangyazsu@gmail.com, wangya@psych.ac.cn
Contribution Rank1
Abstract

OBJECTIVE: Patients with schizophrenia and individuals with schizotypy, a subclinical group at risk for schizophrenia, have been found to have impairments in cognitive control. The Dual Mechanisms of Cognitive Control (DMC) framework hypothesises that cognitive control can be divided into proactive and reactive control. However, it is unclear whether individuals with schizotypy have differential behavioural impairments and neural correlates underlying these two types of cognitive control.

 

METHOD: Twenty-five individuals with schizotypy and 26 matched healthy controls (HCs) completed both reactive and proactive control tasks with electroencephalographic data recorded. The proportion of congruent and incongruent trials was manipulated in a classic colour-word Stroop task to induce proactive or reactive control. Proactive control was induced in a context with mostly incongruent (MI) trials and reactive control in a context with mostly congruent (MC) trials. Two event-related potential (ERP) components, medial frontal negativity (MFN, associated with conflict detection) and conflict sustained potential (conflict SP, associated with conflict resolution) were examined.

 

RESULTS: There was no significant difference between the two groups in terms of behavioural results. In terms of ERP results, in the MC context, HC exhibited significantly larger MFN (360-530 ms) and conflict SP (600-1000 ms) amplitudes than individuals with schizotypy. The two groups did not show any significant difference in MFN or conflict SP in the MI context.

 

CONCLUSIONS: The present findings provide initial evidence for dissociation of neural activation between proactive and reactive cognitive control in individuals with schizotypy. These findings help us understand cognitive control deficits in the schizophrenia spectrum.

KeywordSchizotypy Cognitive control Stroop Event-related potentials Reactive control Proactive control
2021-01-29
DOI10.1017/S135561772000137X
Source PublicationJournal of the International Neuropsychological Society
ISSN1469-7661
Pages1-11
Subtype实证研究
Indexed BySCI
WoS QuartileQ1
QuartileQ1
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Document Type期刊论文
Identifierhttp://ir.psych.ac.cn/handle/311026/39227
Collection中国科学院心理健康重点实验室
健康与遗传心理学研究室
Corresponding AuthorWang, Ya
Affiliation1.Neuropsychology and Applied Cognitive Neuroscience Laboratory, Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences
2.Department of Psychology, University of Chinese Academy of Sciences
3.Research Center for Information and Statistics, National Institute of Education Sciences, Beijing, China
4.North China Electric Power University
First Author AffilicationInstitute of Psychology, Chinese Academy of Sciences
Corresponding Author AffilicationInstitute of Psychology, Chinese Academy of Sciences
Recommended Citation
GB/T 7714
Jia, Lu-xia,Qin, Xiao-jing,Cui, Ji-fang,et al. Dissociation of proactive and reactive cognitive control in individuals with schizotypy: an event-related potential study[J]. Journal of the International Neuropsychological Society,2021:1-11.
APA Jia, Lu-xia.,Qin, Xiao-jing.,Cui, Ji-fang.,Shi, Hai-song.,Ye, Jun-yan.,...&Chan, Raymond CK.(2021).Dissociation of proactive and reactive cognitive control in individuals with schizotypy: an event-related potential study.Journal of the International Neuropsychological Society,1-11.
MLA Jia, Lu-xia,et al."Dissociation of proactive and reactive cognitive control in individuals with schizotypy: an event-related potential study".Journal of the International Neuropsychological Society (2021):1-11.
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