Institutional Repository of Key Laboratory of Mental Health, CAS
Cognitive insight is correlated with cognitive impairments and contributes to medication adherence in schizophrenia patients | |
Lui, Simon S. Y.1,2; Lam, Jessica P. Y.2; Lam, Joanna W. S.2; Chui, William W. H.2; Mui, Jolene H. C.2; Siu, Bonnie W. M.2; Cheng, K. M.2; Cheung, Eric F. C.2; Chan, Raymond C. K.3,4 | |
第一作者 | Lui, Simon S. Y. |
通讯作者邮箱 | lsy570@hku.hk (s.s.y. lui) |
心理所单位排序 | 3 |
摘要 | Objective: Cognitive insight refers to the ability to distance oneself from and evaluate one's own beliefs and interpretations. Little is known about whether cognitive insight could influence medication adherence in schizophrenia patients. This study examined the role of cognitive insight in medication adherence and how it would interact with neuropsychological functions. Methods: Ninety clinically-stable schizophrenia patients completed the Beck's Cognitive Insight Scale (BCIS) and tasks measuring prospective (PM) and other neurocognitive functions. Medication adherence was estimated using a multi-axial method comprising interview, clinician-rating, pharmacy refill record and pill counting. Correlational and regression analyses were conducted to examine whether cognitive insight and PM would be associated with mediation adherence. Post-hoc mediational analysis was performed to examine the interplay between cognitive insight, PM and medication adherence. Results: Clinical insight and cognitive insight together significantly influenced participants' medication adherence, after neurocognitive functions and psychopathology were accounted for. Time-based PM, compared with other neurocognitive functions, affected medication adherence more strongly. Conclusions: Cognitive insight complements clinical insight in affecting medication adherence in schizophrenia patients. |
关键词 | Cognitive insight Medication adherence Prospective memory Schizophrenia |
2021-06-01 | |
语种 | 英语 |
DOI | 10.1016/j.ajp.2021.102644 |
发表期刊 | ASIAN JOURNAL OF PSYCHIATRY |
ISSN | 1876-2018 |
卷号 | 60页码:7 |
期刊论文类型 | 实证研究 |
收录类别 | SCI |
资助项目 | Philip K.H. Wong Foundation |
出版者 | ELSEVIER |
WOS关键词 | PROSPECTIVE MEMORY IMPAIRMENTS ; ANTIPSYCHOTIC MEDICATION ; VERBAL MEMORY ; 1ST EPISODE ; PERFORMANCE ; DISORDERS ; PSYCHOSIS ; NEUROCOGNITION ; NONADHERENCE ; INDIVIDUALS |
WOS研究方向 | Psychiatry |
WOS类目 | Psychiatry |
WOS记录号 | WOS:000661285600006 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.psych.ac.cn/handle/311026/39731 |
专题 | 中国科学院心理健康重点实验室 |
通讯作者 | Lui, Simon S. Y. |
作者单位 | 1.Univ Hong Kong, Dept Psychiat, Hong Kong, Peoples R China 2.Castle Peak Hosp, Hong Kong, Peoples R China 3.Chinese Acad Sci, Inst Psychol, Neuropsychol & Appl Cognit Neurosci Lab, CAS Key Lab Mental Hlth, Beijing, Peoples R China 4.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China |
推荐引用方式 GB/T 7714 | Lui, Simon S. Y.,Lam, Jessica P. Y.,Lam, Joanna W. S.,et al. Cognitive insight is correlated with cognitive impairments and contributes to medication adherence in schizophrenia patients[J]. ASIAN JOURNAL OF PSYCHIATRY,2021,60:7. |
APA | Lui, Simon S. Y..,Lam, Jessica P. Y..,Lam, Joanna W. S..,Chui, William W. H..,Mui, Jolene H. C..,...&Chan, Raymond C. K..(2021).Cognitive insight is correlated with cognitive impairments and contributes to medication adherence in schizophrenia patients.ASIAN JOURNAL OF PSYCHIATRY,60,7. |
MLA | Lui, Simon S. Y.,et al."Cognitive insight is correlated with cognitive impairments and contributes to medication adherence in schizophrenia patients".ASIAN JOURNAL OF PSYCHIATRY 60(2021):7. |
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