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Cognitive insight is correlated with cognitive impairments and contributes to medication adherence in schizophrenia patients
Lui, Simon S. Y.1,2; Lam, Jessica P. Y.2; Lam, Joanna W. S.2; Chui, William W. H.2; Mui, Jolene H. C.2; Siu, Bonnie W. M.2; Cheng, K. M.2; Cheung, Eric F. C.2; Chan, Raymond C. K.3,4
First AuthorLui, Simon S. Y.
Correspondent Emaillsy570@hku.hk (s.s.y. lui)
Contribution Rank3
Abstract

Objective: Cognitive insight refers to the ability to distance oneself from and evaluate one's own beliefs and interpretations. Little is known about whether cognitive insight could influence medication adherence in schizophrenia patients. This study examined the role of cognitive insight in medication adherence and how it would interact with neuropsychological functions. Methods: Ninety clinically-stable schizophrenia patients completed the Beck's Cognitive Insight Scale (BCIS) and tasks measuring prospective (PM) and other neurocognitive functions. Medication adherence was estimated using a multi-axial method comprising interview, clinician-rating, pharmacy refill record and pill counting. Correlational and regression analyses were conducted to examine whether cognitive insight and PM would be associated with mediation adherence. Post-hoc mediational analysis was performed to examine the interplay between cognitive insight, PM and medication adherence. Results: Clinical insight and cognitive insight together significantly influenced participants' medication adherence, after neurocognitive functions and psychopathology were accounted for. Time-based PM, compared with other neurocognitive functions, affected medication adherence more strongly. Conclusions: Cognitive insight complements clinical insight in affecting medication adherence in schizophrenia patients.

KeywordCognitive insight Medication adherence Prospective memory Schizophrenia
2021-06-01
Language英语
DOI10.1016/j.ajp.2021.102644
Source PublicationASIAN JOURNAL OF PSYCHIATRY
ISSN1876-2018
Volume60Pages:7
Subtype实证研究
Indexed BySCI
Funding ProjectPhilip K.H. Wong Foundation
PublisherELSEVIER
WOS KeywordPROSPECTIVE MEMORY IMPAIRMENTS ; ANTIPSYCHOTIC MEDICATION ; VERBAL MEMORY ; 1ST EPISODE ; PERFORMANCE ; DISORDERS ; PSYCHOSIS ; NEUROCOGNITION ; NONADHERENCE ; INDIVIDUALS
WOS Research AreaPsychiatry
WOS SubjectPsychiatry
WOS IDWOS:000661285600006
Citation statistics
Document Type期刊论文
Identifierhttp://ir.psych.ac.cn/handle/311026/39731
Collection中国科学院心理健康重点实验室
Corresponding AuthorLui, Simon S. Y.
Affiliation1.Univ Hong Kong, Dept Psychiat, Hong Kong, Peoples R China
2.Castle Peak Hosp, Hong Kong, Peoples R China
3.Chinese Acad Sci, Inst Psychol, Neuropsychol & Appl Cognit Neurosci Lab, CAS Key Lab Mental Hlth, Beijing, Peoples R China
4.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China
Recommended Citation
GB/T 7714
Lui, Simon S. Y.,Lam, Jessica P. Y.,Lam, Joanna W. S.,et al. Cognitive insight is correlated with cognitive impairments and contributes to medication adherence in schizophrenia patients[J]. ASIAN JOURNAL OF PSYCHIATRY,2021,60:7.
APA Lui, Simon S. Y..,Lam, Jessica P. Y..,Lam, Joanna W. S..,Chui, William W. H..,Mui, Jolene H. C..,...&Chan, Raymond C. K..(2021).Cognitive insight is correlated with cognitive impairments and contributes to medication adherence in schizophrenia patients.ASIAN JOURNAL OF PSYCHIATRY,60,7.
MLA Lui, Simon S. Y.,et al."Cognitive insight is correlated with cognitive impairments and contributes to medication adherence in schizophrenia patients".ASIAN JOURNAL OF PSYCHIATRY 60(2021):7.
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