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Latent structure of self-report negative symptoms in patients with schizophrenia: A preliminary study
Tam, Michelle H. W.2; Wang Ling-Ling3,4,5; Cheng, Koi-man2; Wong, Jessica O. Y.2; Cheung, Eric F. C.2; Lui, Simon S. Y.1,2; Chan, Raymond C. K.3,4,5
First AuthorTam, Michelle H. W.
Correspondent Emaillsy570@hku.hk (s.s.y. lui) ; rckchan@psych.ac.cn (r.c.k. chan)
Contribution Rank3
Abstract

Introduction: Negative symptoms are associated with poor outcomes and functioning. Latent structure of negative symptoms is important for identifying potential intervention targets for novel treatments. Self-report instruments have been developed to measure negative symptoms. Previous findings on latent structure of negative symptoms are inconsistently and mainly rely on clinician-rated instruments. Method: We aimed to explore the latent structure of the Self-Evaluation of Negative Symptoms Scale (SNS) in 204 clinically-stable outpatients with schizophrenia. Confirmatory factor analysis (CFA) was used to compare the competing models (i.e., one-factor, two-factor and five-factor models), and estimated goodness-of-fit indexes. Other clinician-rated scales for psychopathology and medication side-effects were also collected. Results: The CFA found the five-factor model performing best, with a comparative fit index (CFI) of > 0.95, a Tucker Lewis Index (TLI) of > 0.95, and a root mean square error of approximation (RMSEA) of < 0.06. The robust chi-square difference test for the weighted least squares with mean and variance adjusted estimation (WLSMV) also indicated a significant better fit for the five-factor model. Discussion: Our preliminary findings support a five-factor latent structure of self-report negative symptoms in schizophrenia patients. Further research in this area should utilize multiple clinician-rated and self-report measures, and recruit large and homogeneous samples with schizophrenia.

KeywordNegative symptoms Latent structure Schizophrenia Prominent negative symptoms Self-report scales
2021-07-01
Language英语
DOI10.1016/j.ajp.2021.102680
Source PublicationASIAN JOURNAL OF PSYCHIATRY
ISSN1876-2018
Volume61Pages:7
Subtype实证研究
Indexed BySCI
Funding ProjectCAS Key Laboratory of Mental Health, Institute of Psychology ; Philip K.H. Wong Foundation
PublisherELSEVIER
WOS KeywordCLINICAL-ASSESSMENT INTERVIEW ; MOTIVATION
WOS Research AreaPsychiatry
WOS SubjectPsychiatry
WOS IDWOS:000658657300019
Citation statistics
Document Type期刊论文
Identifierhttp://ir.psych.ac.cn/handle/311026/39734
Collection中国科学院心理健康重点实验室
Corresponding AuthorLui, Simon S. Y.; Chan, Raymond C. K.
Affiliation1.Univ Hong Kong, Dept Psychiat, Hong Kong, Peoples R China
2.Castle Peak Hosp, Hong Kong, Peoples R China
3.Inst Psychol, Neuropsychol & Appl Cognit Neurosci Lab, CAS Key Lab Mental Hlth, Beijing, Peoples R China
4.Inst Psychol, CAS Key Lab Mental Hlth, Beijing, Peoples R China
5.Univ Chinese Acad Sci, Beijing, Peoples R China
Corresponding Author Affilication认知与发展心理学研究室;  Key Laboratory of Mental Health, CAS
Recommended Citation
GB/T 7714
Tam, Michelle H. W.,Wang Ling-Ling,Cheng, Koi-man,et al. Latent structure of self-report negative symptoms in patients with schizophrenia: A preliminary study[J]. ASIAN JOURNAL OF PSYCHIATRY,2021,61:7.
APA Tam, Michelle H. W..,Wang Ling-Ling.,Cheng, Koi-man.,Wong, Jessica O. Y..,Cheung, Eric F. C..,...&Chan, Raymond C. K..(2021).Latent structure of self-report negative symptoms in patients with schizophrenia: A preliminary study.ASIAN JOURNAL OF PSYCHIATRY,61,7.
MLA Tam, Michelle H. W.,et al."Latent structure of self-report negative symptoms in patients with schizophrenia: A preliminary study".ASIAN JOURNAL OF PSYCHIATRY 61(2021):7.
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