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早发性抑郁及其神经基础
Alternative TitleEarly-onset Depression and Its Neural Basis
王玮文; 谢希; 邵枫
2008
Source Publication心理科学进展
ISSN1671-3710
Volume16Issue:3Pages:411-417
Abstract儿童期和青少年期抑郁(早发性抑郁)表现出与成年期抑郁不同的一些临床症状、药物疗效和生理反应特征,导致这些差异的神经生物学基础目前尚不清楚。儿童期和青少年期神经系统的发展变化可能参与早发性抑郁的病生理,尤其是单胺能神经递质系统结构和功能的变化与早发性抑郁的生理和药物治疗反应密切相关。早发性抑郁动物模型的建立是研究早发性抑郁脑机制的基础,未来研究的重点是发展有效的早发性抑郁治疗药物和早期心理行为干预技术。
Other AbstractChildhood and adolescent depression (early-onset depression) has been found to differ from adult depression in terms of clinical features, neurobiological response and efficacy of antidepressants. The neurobiological mechanisms underlying the differences were poorly understood. Developmental transformations in brain, especially, discrepancy of the maturation of the adrenergic and serotonergic neurotransmitter systems during childhood and adolescence maybe involve in pathophysiology of early-onset depression...
Keyword儿童期 青少年期 早发性抑郁 单胺能神经递质
Subject Area变态心理学
Indexed ByCSCD
Language中文
Funding Project国家自然科学基金项目(30500158,30670708);; 中国科学院重要方向项目(KSCX2-YW-R-131);; 国家基础研究(973)项目(2007CB512306)资助
CSCD IDCSCD:3291990
Citation statistics
Document Type期刊论文
Identifierhttp://ir.psych.ac.cn/handle/311026/3980
Collection中国科学院心理研究所回溯数据库(1956-2010)
Corresponding Author王玮文
Recommended Citation
GB/T 7714
王玮文,谢希,邵枫. 早发性抑郁及其神经基础[J]. 心理科学进展,2008,16(3):411-417.
APA 王玮文,谢希,&邵枫.(2008).早发性抑郁及其神经基础.心理科学进展,16(3),411-417.
MLA 王玮文,et al."早发性抑郁及其神经基础".心理科学进展 16.3(2008):411-417.
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