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社区老年人肌力水平和肌肉含量与抑郁状态的关系
其他题名Relationship between muscle strength level and muscle content and depressive state in community elderly
王雪
导师陈天勇
2021-07
摘要目的:随着人口老龄化的加剧,老年人心理健康问题日益受到人们的关注。抑郁状态是老年阶段最普遍的心理健康问题,受生理、心理和社会等多方面因素的影响。以往心理学研究多注重于心理因素和社会因素与抑郁状态的相关性,较少关注生理因素与老年人抑郁状态的关联。抑郁状态的发生与老年人身体功能自然衰退有关,其中运动系统功能下降是身体衰退的最常见表现。人们逐渐认识到运动功能不但影响老年人的身体健康,也显著影响老年人的心理健康。骨骼肌是老年人运动功能的重要生理物质基础,肌力水平和肌肉含量可能同时与老年人的运动功能和抑郁状态相关联。本研究旨在通过横断面研究及一年后随访,探讨我国社区老年人的肌力水平和肌肉含量与抑郁状态之间的关系,为老年人抑郁状态的管理与预防提供借鉴。 方法:研究对象选自天津市社区居住并且同意加入中国老年人免费体检活动的老年人,并接受全面的老年综合评估内容,最终基线数据纳入受试者1180人,平均年龄(67.22±5.85)岁,其中男性533名,女性647名。该设计采用针对研究对象的一对一问卷调查,问卷内容涵盖受试者人口学资料(性别、年龄、婚姻状况、文化程度),健康状况(睡眠质量、疾病史)及身体活动能力(IPAQ)。体格检查及身体成分测量包括结构性变量(四肢骨骼肌含量),功能性变量(握力和起立行走测试)以及身体质量指数的测定。采用老年人抑郁量表-15项评估老年人抑郁状态发生率,用Logistic回归分析了肌肉力量和肌肉含量与抑郁状态的相关性。一年后随访因新冠疫情的防疫管控限制,有些老年人未能参加随访追踪,共回访综合评估348人,用Logistic回归分析方法分析了老年人肌肉力量与抑郁状态的关联。 结果:(1)根据老年人抑郁量表-15项评分,140名老人处于抑郁状态,检出率为11.9%;70岁以上和65-69岁组老年人抑郁状态检出率分别为16.4%和12.2%,均高于65岁以下组老年人抑郁状态检出率(8.2%),差异有统计学意义(χ2值=12.88,P=0.002)。(2)控制年龄、婚姻状况、文化程度、肥胖、IPAQ、睡眠质量、疾病史,采用多因素Logistic回归模型分析老年男性握力与抑郁状态的关系。结果显示,与握力最大组相比,握力最小组中老年男性抑郁状态发生风险增加,OR(95%CI)为2.41(1.03,5.67)。多因素Logistic回归模型分析老年男性步速与抑郁状态的关系,与步速最慢组(20秒以上)相比,步速10秒以下及10~19秒的老年男性抑郁状态发生风险OR值(95%CI)分别为0.110(0.032,0.382)和0.140(0.041,0.472),P值均<0.05。(3)多因素Logistic回归模型显示,无论是肌力水平或肌肉含量与抑郁状态的关系,还是步速与抑郁状态的关系,老年男性肥胖(BMI≥28kg/m2)与抑郁状态相关;老年女性IPAQ高组(3000MET/week及以上)和中间组(600-2999MET/week)与IPAQ低组(小于600MET/week)相比,与老年女性抑郁状态发生风险负相关,P值均<0.05。(4)一年后随访发现老年人肌肉力量与抑郁状态的关系趋于显著。 结论:老年男性握力、步速和肥胖与抑郁状态相关,而老年女性功能活动性指标(IPAQ)与抑郁状态相关。这些发现为我国老年居民身心健康维护与促进提供了新视角。
其他摘要Objective:With the intensification of population aging, the mental health of the elderly has received increasing attention. Depression symptoms are the most common problem affecting the mental health of the elderly. The occurrence of depressive symptoms in the elderly is the result of the interaction of physiological-psychological-social factors. In the past, psychological research paid more attention to the correlation between psychological and social factors and depressive symptoms, and less attention was paid to the correlation between physiological factors and depressive symptoms in the elderly. The occurrence of depressive symptoms is related to the natural decline of physical function in the elderly, and the decline of motor system function is the most common manifestation of physical decline. People gradually realized that motor function not only affects the physical health of the elderly, but also significantly affects the mental health of the elderly. Skeletal muscle function is an important physiological material basis for elderly exercise function. Muscle strength and muscle content can objectively reflect the relationship between exercise function and depressive symptoms. This study aims to explore the relationship between muscle strength, muscle content and depression in elderly residents in my country through cross-sectional research and follow-up one year later, so as to provide reference for the management and prevention of depression in the elderly. Methods: Subjects were selected from the elderly who lived in the community of Tianjin and agreed to participate in the free physical examination for the elderly in China, and received a comprehensive geriatrics comprehensive assessment. The final baseline data included 1180 subjects, with an average age of (67.22±5.85) years old, including 533 males and 647 females. The design used one-to-one questionnaires for the study subjects, which included demographic data (gender, age, marital status, education level), health status (sleep quality, history of disease) and physical activity ability (IPAQ). Physical examination and body composition measurements included structural variables (skeletal muscle content in the limbs), functional variables (grip strength and stand up walking tests), and measurements of body mass index. The incidence of depression in the elderly was assessed by using the Depression Scale for the Elderly -15 items. Logistic regression was used to analyze the correlation between muscle strength and muscle content and depression. One year later, due to the restriction of the prevention and control of COVID-19, some elderly people were not able to participate in the follow-up. A total of 348 elderly people were revisited and evaluated comprehensively. Logistic regression analysis was used to analyze the correlation between muscle strength and depression status in the elderly. Results: (1) According to the 15-item score of the Depression Scale for the Elderly, 140 elderly people are in a depressed state, and the detection rate is 11.9%; the detection rate of depression in the elderly over 70 and 65-69 years old is 16.4% and 12.2%, respectively , Are higher than the detection rate of depression in the elderly under 65 (8.2%), the difference is statistically significant (χ² value = 12.88, P = 0.002).(2) Controlling age, marital status, education level, obesity, IPAQ, sleep quality, and disease history, a multivariate logistic regression model was used to analyze the relationship between grip strength and depression in elderly men. The results showed that compared with the highest grip strength group, middle-aged and elderly men in the lowest grip strength group had an increased risk of depression, with an OR (95% CI) of 2.41 (1.03, 5.67). The multivariate logistic regression model analyzes the relationship between gait speed and depressive state in elderly men. Compared with the slowest gait group (above 20 seconds), the OR value of the risk of depressive state in elderly men with a gait speed of less than 10 seconds and 10-19 seconds (95%CI) were 0.110 (0.032, 0.382) and 0.140 (0.041, 0.472), respectively, with P <0.05. (3) The multivariate Logistic regression model showed that obesity (BMI≥28kg/m2) was associated with depression in older men, regardless of the relationship between muscle strength level or muscle content and depression, or the relationship between walking speed and depression; Compared with the low IPAQ group (< 600 met /week), the high IPAQ group (3000MET/week and above) and the middle IPAQ group (600-2999 met /week) were negatively correlated with the risk of depression in the elderly women (P <0.05).(4) One year later, it was found that the muscle strength and depression of the elderly tended to be significant. Conclusion: Grip strength, gait speed, and obesity were associated with depressive status in older men, and functional activity index (IPAQ) was associated with depressive status in older women. These findings provide a new perspective for the maintenance and promotion of physical and mental health of elderly residents in China.
关键词肌力水平 肌肉含量 抑郁状态 老年人
学位类型硕士
语种中文
学位名称理学硕士(同等学力硕士)
学位专业健康心理学
学位授予单位中国科学院心理研究所
学位授予地点中国科学院心理研究所
文献类型学位论文
条目标识符https://ir.psych.ac.cn/handle/311026/41573
专题健康与遗传心理学研究室
推荐引用方式
GB/T 7714
王雪. 社区老年人肌力水平和肌肉含量与抑郁状态的关系[D]. 中国科学院心理研究所. 中国科学院心理研究所,2021.
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