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免疫激活对抑郁症谷氨酸和五羟色胺系统的调节
Alternative TitleThe mediation of immune activation on serotonin and glutamate systems in pathological process of depression
楼剑书; 杨晓春; 方杰; 潘建立; 郭建友
2009
Source Publication中国药理学通报
ISSN1001-1978
Volume25Issue:12Pages:1555-1558
Abstract免疫异常与神经递质改变是抑郁症产生的十分重要的因素。近年来,免疫激活产生的细胞因子对抑郁症病理过程的干预作用已成为众多学者研究的热点,亦是新型抗抑郁药的潜在靶点。免疫激活能导致谷氨酸系统和五羟色胺系统的紊乱,该文对此干预作用作一综述。
Keyword抑郁症 谷氨酸 五羟色胺 免疫激活 细胞因子 吲哚胺2 3-二氧化酶
Subject Area生理心理学/生物心理学 ; 变态心理学
Language中文
Funding Project中国科学院心理研究所青年基金资助项目(No08CX043004)
NoteImmunological alterations and changes in neurotransmission are considered to be crucial in the pathological process of depression.An immune activation including increased production of proinflammatory cytokines has repeatedly been described in depression,which shines a clue for new anti-depression therapy.Immune activation will lead to depression through serotonin and glutamate systems.This paper is attempted to review the immune mediated alterations on serotonin and glutamate systems.
Document Type期刊论文
Identifierhttp://ir.psych.ac.cn/handle/311026/4180
Collection中国科学院心理研究所回溯数据库(1956-2010)
Corresponding Author郭建友
Recommended Citation
GB/T 7714
楼剑书,杨晓春,方杰,等. 免疫激活对抑郁症谷氨酸和五羟色胺系统的调节[J]. 中国药理学通报,2009,25(12):1555-1558.
APA 楼剑书,杨晓春,方杰,潘建立,&郭建友.(2009).免疫激活对抑郁症谷氨酸和五羟色胺系统的调节.中国药理学通报,25(12),1555-1558.
MLA 楼剑书,et al."免疫激活对抑郁症谷氨酸和五羟色胺系统的调节".中国药理学通报 25.12(2009):1555-1558.
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