<p>Differences in cognitive deficits in patients with methamphetamine and heroin use disorder compared with healthy controls in a Chinese Han population</p>

doi:10.1016/j.pnpbp.2022.110543

PSYCH OpenIR

	Differences in cognitive deficits in patients with methamphetamine and heroin use disorder compared with healthy controls in a Chinese Han population
	Tian, Yang 1,2; Wang, Dongmei 1,2; Fan, Fusheng 3; Yang, Yin 1,2; Fu, Fabing 3; Wei, Dejun 3; Tang, Shanshan 3; Chen, Jiajing 1,2; Du, Yuxuan 1,2; Zhu, Rongrong 1,2; Li, Yuqing 1,2; Wang, Li 1,2; Zhang, Xiangyang 1,2
通讯作者	Wang, Dongmei(wangdm@psych.ac.cn) ; Zhang, Xiangyang(zhangxy@psych.ac.cn)
摘要	Background and aims: To date, the pattern of heroin-and methamphetamine-induced cognitive impairment is unclear, especially in the Chinese population. The aim of this study was to compare the similarity and heterogeneity of cognitive impairment between heroin and methamphetamine-dependent patients and to link cognitive impairment to drug-related variables.& nbsp;Methods: 567 pure methamphetamine patients, 78 pure heroin patients and 201 healthy volunteers participated in this study. The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) was used to assess cognitive function including immediate memory, visuospatial/constructional index, language, attention, delayed memory, and total scores.& nbsp;Results: Methamphetamine-dependent and heroin-dependent patients performed significantly worse on all RBANS subtest and total scores (all p < 0.05). Moreover, methamphetamine-dependent patients had more delayed memory impairment than heroin-dependent patients (p = 0.02). In addition, some drug-related variables, such as duration of abstinence, age at first drug use, and duration of drug use, were independently associated with memory and visuospatial/constructional index in methamphetamine patients (all p < 0.05). In contrast, none of the drug-related variables were associated with cognitive performance in heroin patients (all p > 0.05).& nbsp;Conclusions: Chronic heroin and methamphetamine patients may exhibit different patterns of cognitive deficits.
关键词	Methamphetamine Heroin Dependence Cognition Drug-related behaviors
	2022-07-13
语种	英语
DOI	10.1016/j.pnpbp.2022.110543
发表期刊	PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
ISSN	0278-5846
卷号	117 页码:7
收录类别	SCI
资助项目	Southwest University of Science and Technology[2021ZD0202102] ; Chinese National Programs for Brain Science and Brain-like Intelligence Technology[31300848] ; Chinese National Programs for Brain Science and Brain-like Intelligence Technology[31800930] ; National Natural Science Foundation of China[153111KYSB20190004] ; CAS International Cooperation Research Program
出版者	PERGAMON-ELSEVIER SCIENCE LTD
WOS关键词	NEUROPSYCHOLOGICAL STATUS ; REPEATABLE BATTERY ; DEPENDENT PATIENTS ; SUBSTANCE-ABUSE ; ABSTINENCE ; DOPAMINE ; OPIATE ; IMPAIRMENT ; ABNORMALITIES ; INDIVIDUALS
WOS研究方向	Neurosciences & Neurology ; Pharmacology & Pharmacy ; Psychiatry
WOS类目	Clinical Neurology ; Neurosciences ; Pharmacology & Pharmacy ; Psychiatry
WOS记录号	WOS:000792923100001
资助机构	Southwest University of Science and Technology ; Chinese National Programs for Brain Science and Brain-like Intelligence Technology ; National Natural Science Foundation of China ; CAS International Cooperation Research Program
引用统计
文献类型	期刊论文
条目标识符	http://ir.psych.ac.cn/handle/311026/42679
通讯作者	Wang, Dongmei; Zhang, Xiangyang
作者单位	1.Chinese Acad Sci, Inst Psychol, CAS Key Lab Mental Hlth, Beijing, Peoples R China 2.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China 3.Xin Hua Drug Rehabil Ctr, Xinhua, Sichuan, Peoples R China
推荐引用方式 GB/T 7714	Tian, Yang,Wang, Dongmei,Fan, Fusheng,et al. Differences in cognitive deficits in patients with methamphetamine and heroin use disorder compared with healthy controls in a Chinese Han population [J]. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY,2022,117:7.
APA	Tian, Yang.,Wang, Dongmei.,Fan, Fusheng.,Yang, Yin.,Fu, Fabing.,...&Zhang, Xiangyang.(2022). Differences in cognitive deficits in patients with methamphetamine and heroin use disorder compared with healthy controls in a Chinese Han population .PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY,117,7.
MLA	Tian, Yang,et al." Differences in cognitive deficits in patients with methamphetamine and heroin use disorder compared with healthy controls in a Chinese Han population ".PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY 117(2022):7.