A systematic review and meta-analysis on prevalence of and risk factors associated with depression, anxiety and insomnia in infectious diseases, including COVID-19: a call to action | |
Yuan, Kai1; Zheng, Yong-Bo1,2; Wang, Yi-Jie2; Sun, Yan-Kun1; Gong, Yi-Miao1; Huang, Yue-Tong1; Chen, Xuan3; Liu, Xiao-Xing1; Zhong, Yi1,2; Su, Si-Zhen1; Gao, Nan3; Lu, Yi-Long4; Wang, Zhe1; Liu, Wei-Jian1; Que, Jian-Yu1; Yang, Ying-Bo3; Zhang, An-Yi1; Jing, Meng-Ni5; Yuan, Chen-Wei6; Zeng, Na7,8,9,10; Vitiello, Michael V.11; Patel, Vikram12; Fazel, Seena13; Minas, Harry14; Thornicroft, Graham15,16; Fan, Teng-Teng1; Lin, Xiao1; Yan, Wei1; Shi, Le1; Shi, Jie7,8; Kosten, Thomas17; Bao, Yan-Ping7,8,9; Lu, Lin1,2,7,8 | |
第一作者 | Kai Yuan |
通讯作者邮箱 | kosten@bcm.edu ; baoyp@bjmu.edu.cn ; linlu@bjmu.edu.cn |
心理所单位排序 | 6 |
摘要 | Infectious disease epidemics have become more frequent and more complex during the 21(st) century, posing a health threat to the general public and leading to psychological symptoms. The current study was designed to investigate the prevalence of and risk factors associated with depression, anxiety and insomnia symptoms during epidemic outbreaks, including COVID-19. We systematically searched the PubMed, Embase, Web of Science, OVID, Medline, Cochrane databases, bioRxiv and medRxiv to identify studies that reported the prevalence of depression, anxiety or insomnia during infectious disease epidemics, up to August 14(th), 2020. Prevalence of mental symptoms among different populations including the general public, health workers, university students, older adults, infected patients, survivors of infection, and pregnant women across all types of epidemics was pooled. In addition, prevalence of mental symptoms during COVID-19 was estimated by time using meta-regression analysis. A total of 17,506 papers were initially retrieved, and a final of 283 studies met the inclusion criteria, representing a total of 948,882 individuals. The pooled prevalence of depression ranged from 23.1%, 95% confidential intervals (95% CI: [13.9-32.2]) in survivors to 43.3% (95% CI: [27.1-59.6]) in university students, the pooled prevalence of anxiety ranged from 25.0% (95% CI: [12.0-38.0]) in older adults to 43.3% (95% CI: [23.3-63.3]) in pregnant women, and insomnia symptoms ranged from 29.7% (95% CI: [24.4-34.9]) in the general public to 58.4% (95% CI: [28.1-88.6]) in university students. Prevalence of moderate-to-severe mental symptoms was lower but had substantial variation across different populations. The prevalence of mental problems increased over time during the COVID-19 pandemic among the general public, health workers and university students, and decreased among infected patients. Factors associated with increased prevalence for all three mental health symptoms included female sex, and having physical disorders, psychiatric disorders, COVID infection, colleagues or family members infected, experience of frontline work, close contact with infected patients, high exposure risk, quarantine experience and high concern about epidemics. Frequent exercise and good social support were associated with lower risk for these three mental symptoms. In conclusion, mental symptoms are common during epidemics with substantial variation across populations. The population-specific psychological crisis management are needed to decrease the burden of psychological problem and improve the mental wellbeing during epidemic. |
2022-06-06 | |
语种 | 英语 |
DOI | 10.1038/s41380-022-01638-z |
发表期刊 | MOLECULAR PSYCHIATRY |
ISSN | 1359-4184 |
页码 | 9 |
期刊论文类型 | 实证研究 |
收录类别 | SCI |
资助项目 | National Key Research and Development Program of China[2021YFC0863700] ; National Key Research and Development Program of China[2019YFA0706200] ; National Key Research and Development Program of China[2019YFC0118502] ; National Natural Science Foundation of China[81761128036] ; National Natural Science Foundation of China[81821092] ; National Natural Science Foundation of China[82171514] ; National Natural Science Foundation of China[82001404] ; National Natural Science Foundation of China[81901345] ; PKU-Baidu Fund[2020BD011] |
出版者 | SPRINGERNATURE |
WOS关键词 | MENTAL-HEALTH-CARE ; POSTTRAUMATIC-STRESS ; MEDICAL WORKERS ; CHINA ; EPIDEMIC ; SURVIVORS ; OUTBREAK ; IMPACT |
WOS研究方向 | Biochemistry & Molecular Biology ; Neurosciences & Neurology ; Psychiatry |
WOS类目 | Biochemistry & Molecular Biology ; Neurosciences ; Psychiatry |
WOS记录号 | WOS:000806685800004 |
WOS分区 | Q1 |
资助机构 | National Key Research and Development Program of China ; National Natural Science Foundation of China ; PKU-Baidu Fund |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.psych.ac.cn/handle/311026/42772 |
专题 | 健康与遗传心理学研究室 |
通讯作者 | Kosten, Thomas; Bao, Yan-Ping; Lu, Lin |
作者单位 | 1.Peking Univ, Natl Clin Res Ctr Mental Disorders, Peking Univ Sixth Hosp,Res Unit 2018RU006, Inst Mental Hlth,NHC Key Lab Mental Hlth,Chinese, Beijing, Peoples R China 2.Peking Univ, McGovern Inst Brain Res, Peking Tsinghua Ctr Life Sci & PKU IDG, Beijing, Peoples R China 3.Xinxiang Med Univ, Affiliated Hosp 1, Xinxiang, Henan, Peoples R China 4.Peking Univ, Sch Psychol & Cognit Sci, Beijing, Peoples R China 5.Renmin Univ China, Dept Psychol, Beijing, Peoples R China 6.Chinese Acad Sci, Inst Psychol, Beijing, Peoples R China 7.Peking Univ, Natl Inst Drug Dependence, Beijing, Peoples R China 8.Peking Univ, Beijing Key Lab Drug Dependence, Beijing, Peoples R China 9.Peking Univ, Sch Publ Hlth, Beijing, Peoples R China 10.Capital Med Univ, Beijing Friendship Hosp, Beijing, Peoples R China 11.Univ Washington, Dept Psychiat & Behav Sci, Seattle, WA 98195 USA 12.Harvard Med Sch, Dept Global Hlth & Social Med, Boston, MA USA 13.Univ Oxford, Dept Psychiat, Oxford, England 14.Univ Melbourne, Ctr Mental Hlth, Sch Populat & Global Hlth, Global & Cultural Mental Hlth Unit, Melbourne, Vic, Australia 15.Kings Coll London, Ctr Global Mental Hlth, Inst Psychiat Psychol & Neurosci, London, England 16.Kings Coll London, Ctr Implementat Sci, Inst Psychiat Psychol & Neurosci, London, England 17.Baylor Coll Med, Dept Psychiat Pharmacol Neurosci Immunol, Houston, TX 77030 USA |
推荐引用方式 GB/T 7714 | Yuan, Kai,Zheng, Yong-Bo,Wang, Yi-Jie,et al. A systematic review and meta-analysis on prevalence of and risk factors associated with depression, anxiety and insomnia in infectious diseases, including COVID-19: a call to action[J]. MOLECULAR PSYCHIATRY,2022:9. |
APA | Yuan, Kai.,Zheng, Yong-Bo.,Wang, Yi-Jie.,Sun, Yan-Kun.,Gong, Yi-Miao.,...&Lu, Lin.(2022).A systematic review and meta-analysis on prevalence of and risk factors associated with depression, anxiety and insomnia in infectious diseases, including COVID-19: a call to action.MOLECULAR PSYCHIATRY,9. |
MLA | Yuan, Kai,et al."A systematic review and meta-analysis on prevalence of and risk factors associated with depression, anxiety and insomnia in infectious diseases, including COVID-19: a call to action".MOLECULAR PSYCHIATRY (2022):9. |
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A systematic review (1283KB) | 期刊论文 | 出版稿 | 限制开放 | CC BY-NC-SA | 请求全文 |
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